Clinical Trial Update: Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis [Phase 3]

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Summary

A Phase 3 trial comparing cyclophosphamide with methotrexate plus a calcineurin inhibitor for GVHD prophylaxis in patients with various hematologic malignancies…

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Diseases / indications

• Acute Lymphoblastic Leukemia
• Acute Myeloid Leukemia
• Chronic Myeloid Leukemia
• Myelodysplastic Syndromes
• Myelomonocytic Leukemia
• Myeloproliferative Neoplasm

Drugs mentioned

• CYCLOPHOSPHAMIDE (Cyclophosphamide)
• CYCLOSPORINE (cyclosporine)
• METHOTREXATE (METHOTREXATE)
• Tacrolimus (Tacrolimus)

Snippet

Sponsor: Hospital Israelita Albert Einstein | Conditions: Acute Myelogenous Leukemia, Acute Lymphoid Leukemia | Phase 3 | Status: TERMINATED