Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2009-12-08Clinical Trial Update: Safety Study of Combined Chemotherapy and Endostar to Untreated Patients With Advanced Melanoma [Phase 2]
A Phase 2 safety study evaluating the combination of chemotherapy and Endostar in untreated patients with advanced melanoma.
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CLINICAL_TRIALS trial_result · 2009-12-02Clinical Trial Update: Active Specific Intranodal Immunotherapy of Recombinant Vaccinia Virus in Locally Advanced to Metastatic Melanoma [Phase 1, Phase 2]
A phase 1/2 clinical trial of active specific intranodal immunotherapy using a recombinant vaccinia virus in locally advanced to metastatic …
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CLINICAL_TRIALS trial_result · 2009-11-11Clinical Trial Update: Evaluation of Pigmented Skin Lesions With MelaFind(R) System [Phase 3]
Phase 3 trial evaluating the MelaFind diagnostic system for pigmented skin lesions in melanoma completed with results posted in 2009.
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CLINICAL_TRIALS research · 2009-10-27Clinical Trial Update: The Identification of Novel Prognostic Markers in Melanoma
This document reports a clinical trial update focused on identifying novel prognostic markers in melanoma.
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CLINICAL_TRIALS trial_result · 2009-10-21Clinical Trial Update: A Pilot Study of Intraoperative Gamma Camera Imaging During Sentinel Node Biopsy for Melanoma
A pilot study evaluated the use of intraoperative gamma camera imaging during sentinel lymph node biopsy in melanoma patients; the trial sta…
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CLINICAL_TRIALS trial_result · 2009-09-29Clinical Trial Update: Peptide-pulsed vs. RNA-transfected Dendritic Cell Vaccines in Melanoma Patients [Phase 1, Phase 2]
Phase 1/2 trial comparing peptide-pulsed dendritic cell vaccines with RNA-transfected dendritic cell vaccines in melanoma patients (stage II…
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CLINICAL_TRIALS trial_result · 2009-09-15Clinical Trial Update: Intraoperative Mapping of Regional Lymphatics Draining the Primary Site of Melanoma Using Isosulfan Blue
A completed clinical trial assessed intraoperative mapping of regional lymphatics draining the primary site of melanoma using the blue dye i…
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CLINICAL_TRIALS trial_result · 2009-06-11Clinical Trial Update: Safety Study of CADI-05 in Patients With Advanced Stage Melanoma [Phase 1, Phase 2]
The safety study of CADI-05 in patients with advanced-stage melanoma has been terminated (Phase 1/Phase 2).
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CLINICAL_TRIALS research · 2009-06-03Clinical Trial Update: Evaluation of the Effects of Local Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Adjuvant Administration on Dendritic Cells in Skin of Melanoma Patients and in Sentinel Lymph Nodes: MEL38 [NA]
A completed clinical trial (MEL38) evaluated local GM-CSF as an adjuvant in melanoma patients, analyzing dendritic cell effects in the skin …
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CLINICAL_TRIALS trial_result · 2009-05-15Clinical Trial Update: A Study to Assess the Safety and Pharmacokinetics of an Inhibitor of PARP in Combination With Dacarbazine [Phase 1]
A Phase 1 trial evaluated the safety and pharmacokinetics of a PARP inhibitor in combination with dacarbazine for melanoma, and the study is…
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CLINICAL_TRIALS trial_result · 2009-05-11Clinical Trial Update: A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma [Phase 1, Phase 2]
A Phase 1/2 safety and efficacy study of intravenous 131I-TM601 in adults with malignant melanoma was conducted, but the trial was terminate…
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CLINICAL_TRIALS trial_result · 2009-04-03Clinical Trial Update: Bevacizumab, Dacarbazine and Interferon-Alfa to Treat Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating bevacizumab with dacarbazine and interferon-alfa for metastatic melanoma, which has completed.
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CLINICAL_TRIALS trial_result · 2009-03-31Clinical Trial Update: 131-I-TM-601 Study in Adults With Solid Tumors [Phase 1]
Phase 1 update on the radiopharmaceutical 131I-TM-601 in adults with solid tumors, including breast cancer, non-small cell lung cancer, mela…
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EMA withdrawal · 2009-03-16EMA Application withdrawn: Cylatron (peginterferon alfa-2b) — SP Europe
European Medicines Agency report indicates withdrawal of the application for Cylatron (peginterferon alfa-2b) for melanoma by SP Europe.
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CLINICAL_TRIALS trial_result · 2009-03-12Clinical Trial Update: Temozolomide Versus Dacarbazine in Stage IV Metastatic Melanoma (Study P03267) [Phase 3]
A Phase 3 trial comparing temozolomide to dacarbazine in stage IV metastatic melanoma has completed, with results posted in 2009.
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CLINICAL_TRIALS trial_result · 2009-03-12Clinical Trial Update: PF-3512676 (CPG 7909) Injection For Patients Who Completed An Oncology Study Using PF-3512676 (CPG 7909) [Phase 2]
Phase 2 clinical trial update on PF-3512676 (CPG 7909) for patients who completed an oncology study using the drug. The document notes that …
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CLINICAL_TRIALS trial_result · 2009-03-11Clinical Trial Update: A Study of Intravenous INO-1001 Plus Oral Temozolomide to Evaluate Tolerability, Safety, and Pharmacokinetics in Patients With Melanoma [Phase 1]
A Phase 1 study evaluating tolerability, safety, and pharmacokinetics of intravenous INO-1001 combined with oral temozolomide in patients wi…
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CLINICAL_TRIALS trial_result · 2009-02-19Clinical Trial Update: Dendritic Cell Vaccination in Melanoma Patients Scheduled for Regional Lymph Node Dissection [Phase 1, Phase 2]
This clinical trial update evaluates autologous dendritic cell vaccination in melanoma patients scheduled for regional lymph node dissection…
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CLINICAL_TRIALS trial_result · 2009-02-19Clinical Trial Update: Augmentation of Dendritic Cell-Based Vaccines in Melanoma Patients by Depletion of Regulatory T Cells in Stage IV Melanoma Patients [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluated whether depleting regulatory T cells could enhance dendritic cell–based vaccines in stage IV melanoma; …
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CLINICAL_TRIALS trial_result · 2009-02-10Clinical Trial Update: CPG 7909 Injection in Melanoma [Phase 2]
Pfizer conducted a Phase 2 trial of CPG 7909 Injection in melanoma. The study status is reported as completed.
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CLINICAL_TRIALS trial_result · 2009-02-09Clinical Trial Update: Vaccine Therapy in Treating Patients With Primary Stage II Melanoma [Phase 3]
A Phase 3 clinical trial of a vaccine therapy for primary stage II melanoma is underway, but the current status is not disclosed.
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CLINICAL_TRIALS trial_result · 2009-02-09Clinical Trial Update: Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma [Phase 2]
This document provides an update on a Phase 2 clinical trial of a vaccine therapy for stage III or stage IV melanoma.
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CLINICAL_TRIALS trial_result · 2009-02-02Clinical Trial Update: Exploratory, Phase 0 Study of Positron Emission Tomography (PET) Imaging Agent, F-18 RGD-K5 [EARLY_Phase 1]
Siemens Molecular Imaging completed an exploratory Phase 0 PET imaging study of the F-18 RGD-K5 tracer. The study evaluated imaging across m…
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CLINICAL_TRIALS trial_result · 2008-10-27Clinical Trial Update: Use of 852A in Metastatic Cutaneous Melanoma. [Phase 2]
Pfizer completed a Phase 2 trial evaluating the agent 852A in patients with unresectable or metastatic cutaneous melanoma.
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CLINICAL_TRIALS trial_result · 2008-10-27Clinical Trial Update: Safety and Efficacy of an Immune Response Modifier to Treat Inoperable Advanced Melanoma Skin Lesions [Phase 1]
Pfizer conducted a Phase 1 trial to assess the safety and early efficacy of an immune response modifier for inoperable advanced melanoma ski…