Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-27Clinical Trial Results: Substudy 02C: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Stage III Melanoma Who Are Candidates for Neoadjuvant Therapy (MK-3475-02C/KEYMAKER-U02) [Phase 1, Phase 2]
Phase 1/2 trial evaluating pembrolizumab with or without investigational agents as neoadjuvant therapy in stage III melanoma; results comple…
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CLINICAL_TRIALS trial_result · 2026-08-17Clinical Trial Results: Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies [Phase 1, Phase 2]
Phase 1/2 trial evaluating a triple immune checkpoint blockade (INCMGA00012 anti-PD-1, INCAGN02385 anti-LAG-3, INCAGN02390 anti-TIM-3) in ad…
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CLINICAL_TRIALS trial_result · 2026-08-13Clinical Trial Results: Substudy 02A: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents in Participants With Programmed Cell-death 1 (PD-1) Refractory Melanoma (MK-3475-02A/KEYMAKER-U02) [Phase 1, Phase 2]
Phase 1/2 substudy evaluating pembrolizumab in combination with investigational agents for PD-1 refractory melanoma; results completed and p…
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CLINICAL_TRIALS trial_result · 2026-08-06Clinical Trial Results: High Dose IL-2 in Combination With Anti-PD-1 [Phase 2]
Phase 2 trial evaluating high-dose interleukin-2 in combination with anti-PD-1 in melanoma and renal cell carcinoma (metastatic); study term…
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CLINICAL_TRIALS trial_result · 2026-07-30Clinical Trial Results: Study of HBI-8000 With Nivolumab in Melanoma, Renal Cell Carcinoma and Non-Small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating HBI-8000 in combination with nivolumab for melanoma, renal cell carcinoma, and non-small cell lung cance…
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CLINICAL_TRIALS trial_result · 2026-07-23Clinical Trial Results: NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours [Phase 1, Phase 2]
Phase 1/2 trial results of NUC-3373 in combination with other agents in patients with advanced solid tumors; study status terminated with re…
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CLINICAL_TRIALS trial_result · 2026-07-09Clinical Trial Results: A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study of pegylated IL-10 (pegilodecakin) in adults with advanced solid tumors; results from a first-in-human trial assessing safety …
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CLINICAL_TRIALS trial_result · 2026-07-02Clinical Trial Results: Study of TLR9 Agonist Vidutolimod (CMP-001) in Combination With Nivolumab vs. Nivolumab [Phase 2]
Phase 2 study evaluating TLR9 agonist vidutolimod (CMP-001) in combination with nivolumab versus nivolumab alone in melanoma; results comple…
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CLINICAL_TRIALS trial_result · 2026-06-18Clinical Trial Results: Family Lifestyles, Actions, and Risk Education Intervention: Version 2 [NA]
A completed clinical trial evaluating a family lifestyle and risk education intervention related to melanoma in children.
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CLINICAL_TRIALS trial_result · 2026-06-16Clinical Trial Results: Nivolumab in Treating Patients With Stage IIB-IIC Melanoma That Can Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating nivolumab as treatment for Stage IIB-IIC melanoma that can be surgically removed; results completed with results po…
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CLINICAL_TRIALS trial_result · 2026-06-04Clinical Trial Results: Pembrolizumab and Lenvatinib in Patients With Brain Metastases From Melanoma or Renal Cell Carcinoma [Phase 2]
Phase 2 trial evaluating pembrolizumab plus lenvatinib for brain metastases from melanoma or renal cell carcinoma; study terminated with res…
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CLINICAL_TRIALS trial_result · 2026-06-03Clinical Trial Update: A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable Melanoma [Phase 3]
Phase 3 trial update on subcutaneous nivolumab plus relatlimab fixed-dose combination for previously untreated metastatic or unresectable me…
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CLINICAL_TRIALS trial_result · 2026-06-03Clinical Trial Results: IT-hu14.18-IL2 With Radiation, Nivolumab and Ipilimumab for Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating IT-hu14.18-IL2 with radiation, nivolumab and ipilimumab in melanoma; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Superparamagnetic Iron Oxide for Sentinel Lymph Node Localization in Patients With Cutaneous Melanoma, a Randomized Phase III Multi-center Non- Inferiority Trial: MagMen-II [Phase 3]
A Phase III randomized non-inferiority trial evaluating superparamagnetic iron oxide for sentinel lymph node localization in cutaneous melan…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Rigosertib Plus Pembrolizumab in Treating Patients With Unresectable/Metastatic Melanoma Refractory to PD-1 Inhibitors [Phase 2]
Phase 2 trial evaluating rigosertib in combination with pembrolizumab for unresectable or metastatic melanoma that is refractory to PD-1 inh…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating immunotherapy or targeted therapy with or without stereotactic radiosurgery for brain metastases from melanoma or…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Trial of Pembrolizumab and Radiotherapy in Melanoma [Phase 2]
A Phase 2 trial evaluating pembrolizumab in combination with radiotherapy for melanoma has been terminated, with results posted on 2026-04-2…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Aerosolized Aldesleukin in Treating Patients With Lung Metastases [Phase 1]
Phase 1 study evaluating aerosolized aldesleukin (interleukin-2) in patients with cancers that have metastasized to the lung, including mela…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: A Phase 1/2 Randomized, Blinded, Placebo Controlled Study of Ipilimumab in Combination With Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma [Phase 1, Phase 2]
A phase 1/2 randomized trial evaluated ipilimumab plus epacadostat vs ipilimumab plus placebo in unresectable or metastatic melanoma; the st…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies [Phase 1]
Phase 1 trial evaluating CTX-471 as a monotherapy or in combination with pembrolizumab in patients who progressed after PD-1/PD-L1 inhibitor…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Genetically Modified T-Cells Followed by Aldesleukin in Treating Patients With Stage III-IV Melanoma [Phase 1]
Phase 1 trial from MD Anderson evaluating genetically modified T-cells followed by Aldesleukin in patients with stage III to IV melanoma. Th…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: TNF in Melanoma Patients Treated With Immunotherapy [NA]
A completed clinical trial sponsored by Institut Claudius Regaud studied tumor necrosis factor (TNF) in melanoma patients treated with immun…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer [Phase 1]
A Phase 1 trial update investigates pembrolizumab in combination with aflibercept in patients with advanced cancers, including melanoma, col…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Testing the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating navitoclax in combination with dabrafenib and trametinib for patients with BRAF-mutant melanoma; th…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Study of TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study of TransCon TLR7/8 agonist with or without pembrolizumab in patients with advanced or metastatic solid tumors has been ter…