Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2008-10-24Clinical Trial Update: Comparative Study of Individualized Sensitivity-Directed Chemotherapy Versus DTIC [Phase 3]
Phase 3 study comparing individualized sensitivity-directed chemotherapy to dacarbazine in melanoma. Current status is unknown.
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CLINICAL_TRIALS trial_result · 2008-08-05Clinical Trial Update: Volociximab in Combination With DTIC in Patients With Metastatic Melanoma Not Previously Treated With Chemotherapy [Phase 2]
Phase 2 trial evaluating volociximab in combination with dacarbazine in patients with metastatic melanoma not previously treated with chemot…
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CLINICAL_TRIALS trial_result · 2008-07-25Clinical Trial Update: Chemotherapy With or Without Immunotherapy in Treating Patients With Stage III or Stage IV Melanoma [Phase 3]
A Phase 3 trial comparing chemotherapy with or without immunotherapy for Stage III or Stage IV melanoma has completed.
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CLINICAL_TRIALS trial_result · 2008-07-24Clinical Trial Update: Treatment of Metastatic Melanoma With Autologous Melan-A/MART-1 Specific CTL Clones [Phase 1, Phase 2]
This update reports on a completed Phase 1/2 trial evaluating autologous Melan-A/MART-1–specific cytotoxic T lymphocytes for metastatic mela…
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CLINICAL_TRIALS trial_result · 2008-06-18Clinical Trial Update: Sentinel Node With Ultrasound Contrast in Melanoma [NA]
A completed clinical trial evaluated the use of ultrasound contrast for sentinel lymph node imaging in melanoma.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Immunization of HLA-A201 Patients With Metastatic Melanoma Using a Combination of Immunodominant Peptides From Three Melanoma Antigens, MART-1, GP100 and Tyrosinase [Phase 2]
A Phase 2 trial tested a peptide vaccine made from MART-1, GP100, and Tyrosinase in HLA-A201 patients with metastatic melanoma; the study ha…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Immunization of Patients With Metastatic Melanoma Using the GP100 Peptide Preceded by an Endoplasmic Reticulum Insertion Signal Sequence [Phase 2]
Phase 2 clinical trial update reporting completion of an immunization strategy using the GP100 peptide vaccine with an ER insertion signal s…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Phase I Study of gp100 Human Melanoma Peptide Vaccine With Incomplete Freund's Adjuvant [Phase 1]
Phase I study of the gp100 melanoma peptide vaccine with incomplete Freund's adjuvant has completed, reporting safety and immunogenicity dat…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Randomized Phase III Trial of Hyperthermic Isolated Limb Perfusion With Melphalan, Tumor Necrosis Factor, and Interferon-Gamma in Patients With Locally Advanced Extremity Melanoma [Phase 3]
This document reports on a completed randomized Phase III trial evaluating hyperthermic isolated limb perfusion with melphalan, tumor necros…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer [Phase 1]
A completed Phase I study of oral COL-3 (NSC-683551), an matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer, …
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity [Phase 1]
This is a Phase 1 pilot trial update evaluating melphalan perfusion for in-transit melanoma or unresectable extremity sarcoma, which has com…
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CLINICAL_TRIALS trial_result · 2008-01-15Clinical Trial Update: Evaluating The Antitumor Activity Of MEDI-522 With Or Without Dacarbazine In Patients With Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating MEDI-522 with or without dacarbazine for metastatic melanoma has completed.
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CLINICAL_TRIALS research · 2007-12-06Clinical Trial Update: Randomized Trial of ATN-224 and Temozolomide in Advanced Melanoma [Phase 2]
Clinical trial update for a Phase 2 randomized study of ATN-224 in combination with temozolomide in advanced melanoma; current status is unk…
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CLINICAL_TRIALS trial_result · 2007-11-16Clinical Trial Update: Phase I/II Study of Chemo-Immunotherapy Combination in Melanoma Patients [Phase 1]
An early-phase (Phase I/II) trial of a chemo-immunotherapy combination for melanoma has completed Phase 1, according to the update. The docu…
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CLINICAL_TRIALS trial_result · 2007-09-20Clinical Trial Update: Safety and Immunogenicity of a Melan-A VLP Vaccine in Advanced Stage Melanoma Patients [Phase 1, Phase 2]
This update reports safety and immunogenicity data from a Phase 1/2 trial of a Melan-A virus-like particle vaccine in patients with advanced…
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CLINICAL_TRIALS trial_result · 2007-08-23Clinical Trial Update: Intralesional PV-10 Chemoablation of Metastatic Melanoma [Phase 1]
Phase 1 trial update of intralesional PV-10 for metastatic melanoma reports the study has been completed. PV-10 is a Rose Bengal disodium–ba…
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CLINICAL_TRIALS trial_result · 2007-08-14Clinical Trial Update: Vaccination of Melanoma Patients With Dendritic Cells Loaded With Allogeneic Apoptotic-Necrotic Melanoma Cells [Phase 1]
Phase 1 trial evaluating dendritic cells loaded with allogeneic apoptotic-necrotic melanoma cells as a vaccine in melanoma patients has comp…
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CLINICAL_TRIALS trial_result · 2007-06-08Clinical Trial Update: Study of Talabostat and Cisplatin in Advanced Melanoma [Phase 2]
A Phase 2 trial evaluating talabostat in combination with cisplatin for advanced melanoma has completed.
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CLINICAL_TRIALS trial_result · 2007-06-08Clinical Trial Update: Study of Talabostat in Advanced Melanoma [Phase 2]
A Phase 2 clinical trial of talabostat in advanced melanoma has completed.
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CLINICAL_TRIALS trial_result · 2007-03-01Clinical Trial Update: Sub-Tenon Triamcinolone in the Prevention of Radiation-Induced Macular Edema [NA]
Completed clinical trial evaluating sub-Tenon triamcinolone to prevent radiation-induced macular edema in melanoma patients.
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CLINICAL_TRIALS research · 2006-12-06Clinical Trial Update: Melanoma Inhibitory Activity (MIA): A Serological Marker for Metastatic Uveal Melanoma
This clinical trial update discusses Melanoma Inhibitory Activity (MIA) as a serological marker for metastatic uveal melanoma. The sponsor i…
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CLINICAL_TRIALS research · 2006-06-21Clinical Trial Update: Standard Palliative Care Versus Standard Palliative Care Plus Polychemotherapy in Metastasized Malignant Melanoma [Phase 4]
An ongoing Phase 4 trial compares standard palliative care alone versus standard palliative care plus polychemotherapy in metastatic melanom…
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CLINICAL_TRIALS trial_result · 2006-06-21Clinical Trial Update: Standard High-Dose Alpha Interferon Versus Intermittent High-Dose Alpha Interferon [Phase 3]
Phase 3 trial comparing standard high-dose alpha interferon with intermittent high-dose alpha interferon in adjuvant Stage III melanoma.
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FDA approval ·FDA Approves New Engineered Viral Immunotherapy for Patients with Treatment-Resistant Advanced Melanoma
FDA grants accelerated approval for Tudriqev (vusolimogene oderparepvec-wtpg), a genetically modified oncolytic viral therapy for treatment-…