Melanoma
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CLINICAL_TRIALS trial_result · 2010-10-21Clinical Trial Update: Trial for the Evaluation of the Effect of Systemic Low-dose Interleukin-2 (IL-2) on the Immunogenicity of a Vaccine Comprising Synthetic Melanoma Peptides Administered With Granulocyte-macrophage Colony-stimulating Factor (GM-CSF)-In-Adjuvant, in Patients With High Risk Melanoma [Phase 2]
Phase 2 trial evaluating the immunogenicity of a synthetic melanoma peptide vaccine administered with GM-CSF in combination with systemic lo…
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CLINICAL_TRIALS research · 2010-10-18Clinical Trial Update: A Survey Study to See if Patients Diagnosed With Parkinson's Disease Have Higher Incidence of Melanoma
A completed survey study investigating whether patients with Parkinson's disease have a higher incidence of melanoma.
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CLINICAL_TRIALS trial_result · 2010-10-13Clinical Trial Update: PegIntron Versus IntronA in CMAJCC Stage II (EADO 2001/CMII Trial) [Phase 3]
Phase 3 trial comparing pegylated interferon alfa-2b (PegIntron) with interferon alfa-2b (IntronA) in CMAJCC Stage II; the study has complet…
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CLINICAL_TRIALS research · 2010-10-07Clinical Trial Update: Sorafenib and Temozolomide in Treating Patients With Stage III or Stage IV Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the combination of Sorafenib and Temozolomide in patients with stage III or stage IV melanoma.
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CLINICAL_TRIALS trial_result · 2010-09-21Clinical Trial Update: Biological Therapy in Treating Patients With Metastatic Melanoma [Phase 1]
This clinical trial update notes the completion status of a Phase 1 study of a biological therapy in patients with metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2010-08-23Clinical Trial Update: Phase 1 Study of MPC-6827 and Temozolomide in Metastatic Melanoma [Phase 1, Phase 2]
Phase 1/2 clinical trial of MPC-6827 with temozolomide for metastatic melanoma has completed its evaluation.
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CLINICAL_TRIALS trial_result · 2010-08-18Clinical Trial Update: Trial of Surgical Excision Margins in Thick Primary Melanoma [NA]
Completed Karolinska Institutet clinical trial evaluating surgical excision margins in thick primary melanoma.
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CLINICAL_TRIALS trial_result · 2010-08-06Clinical Trial Update: Cyclophosphamide, Autologous Lymphocytes, and Aldesleukin in Treating Patients With Metastatic Melanoma
The clinical trial investigating cyclophosphamide, autologous lymphocytes, and aldesleukin for metastatic melanoma is no longer available.
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CLINICAL_TRIALS trial_result · 2010-08-05Clinical Trial Update: Efficacy Study of TLN-232 in Patients With Recurring Metastatic Melanoma [Phase 2]
Phase 2 efficacy study of TLN-232 in patients with recurring metastatic melanoma has been terminated.
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CLINICAL_TRIALS trial_result · 2010-08-03Clinical Trial Update: Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer. [Phase 1]
Phase 1 trial assessing safety and immune response of MKC1106-PP in patients with advanced cancer, including ovarian cancer and melanoma; th…
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CLINICAL_TRIALS trial_result · 2010-08-03Clinical Trial Update: Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma. [Phase 1]
A Phase 1 trial evaluating MKC1106-MT in patients with melanoma reports safety data and immune responses from a multi-component immunotherap…
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CLINICAL_TRIALS trial_result · 2010-05-26Clinical Trial Update: Multiepitope Peptide Vaccination in Melanoma [Phase 2]
A Phase 2 clinical trial evaluating a multiepitope peptide vaccination for metastatic melanoma is ongoing, sponsored by Charité University i…
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CLINICAL_TRIALS trial_result · 2010-05-10Clinical Trial Update: Phase II Study With Immunotherapy With Dendritic Cells and Tumor Infiltrating Lymphocytes in Solid Tumors [Phase 2]
Phase II trial evaluating dendritic cell-based immunotherapy in combination with tumor-infiltrating lymphocytes for solid tumors including r…
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CLINICAL_TRIALS trial_result · 2010-05-10Clinical Trial Update: Biological Therapy in Treating Patients With Metastatic Melanoma [Phase 1, Phase 2]
Clinical trial update for a biological therapy in treating metastatic melanoma; the study completed in Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2010-05-07Clinical Trial Update: Biological Therapy in Treating Patients With Metastatic Melanoma [Phase 1]
Phase 1 clinical trial evaluating a biological therapy for metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2010-04-26Clinical Trial Update: Dendritic Cell Based Therapy of Malignant Melanoma [Phase 1, Phase 2]
A dendritic cell–based therapy for advanced melanoma has completed Phase 1 and Phase 2 trials.
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CLINICAL_TRIALS research · 2010-04-26Clinical Trial Update: Long-term Data Collection for Subjects in MDX-010 Studies
An update indicating ongoing long-term data collection for subjects enrolled in MDX-010 studies (ipilimumab) for metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2010-04-15Clinical Trial Update: The Impact of Total Body Skin Examination on Skin Cancer Detection [NA]
A completed clinical trial evaluating the impact of total body skin examinations on the detection of skin cancers, including melanoma and ba…
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CLINICAL_TRIALS trial_result · 2010-04-09Clinical Trial Update: Study of gp75 Vaccine in Patients With Stage III and IV Melanoma [Phase 1]
Phase 1 clinical trial of the gp75 vaccine in stage III/IV melanoma has completed.
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CLINICAL_TRIALS trial_result · 2010-03-02Clinical Trial Update: Study of Ipilimumab (MDX-010) Monotherapy in Patients With Previously Treated Unresectable Stage III or IV Melanoma [Phase 2]
A Phase 2 study evaluating ipilimumab monotherapy in previously treated unresectable stage III or IV melanoma has been completed.
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CLINICAL_TRIALS trial_result · 2010-02-03Clinical Trial Update: Safety, Tolerability, and Preliminary Efficacy Study of ALS-357 in Patients With Cutaneous Metastatic Melanoma [Phase 1]
Phase 1 clinical trial update assessing safety, tolerability, and preliminary efficacy of ALS-357 in patients with cutaneous metastatic mela…
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CLINICAL_TRIALS trial_result · 2010-01-08Clinical Trial Update: Monocentric Pilot Study Investigating the Metabolic Activity of Melanoma in Vivo During Sorafenib and Dacarbazine [Phase 2]
Phase 2 monocentric pilot trial assessing metabolic activity of melanoma in vivo during treatment with sorafenib and dacarbazine; the study …
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EMA approval · 2009-12-31EMA Refused: Genasense (oblimersen) — Genta Development Ltd. c/o Ross Craig
The EMA refused approval for Genasense (oblimersen) for melanoma, indicating a negative outcome in the regulatory decision.
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CLINICAL_TRIALS withdrawal · 2009-12-14Clinical Trial Update: Treatment Use Study for Advanced Melanoma.
The Pfizer-sponsored treatment use study for advanced unresectable melanoma is no longer available.
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CLINICAL_TRIALS trial_result · 2009-12-11Clinical Trial Update: Riluzole in Treating Patients With Stage III or Stage IV Melanoma That Can Be Removed by Surgery [Phase 1]
Phase 1 trial evaluating riluzole for surgically resectable stage III or stage IV melanoma was terminated.