Melanoma
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: ctDNA for Early Detection of Recurrence in Melanoma
An update on a trial evaluating ctDNA for the early detection of melanoma recurrence. The study is currently not recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab [Phase 2]
Phase 2 clinical trial evaluating adoptive cell therapy with tumor infiltrating lymphocytes plus interleukin-2 for metastatic melanoma, give…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Immune Checkpoint Inhibitor (ICI)-Drug-Drug Interaction (DDI) Study [EARLY_Phase 1]
An early-phase immune checkpoint inhibitor drug–drug interaction study is described with not-yet-recruiting status, covering gastrointestina…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Evaluation for NCI Surgery Branch Clinical Research Protocols
NCI's Surgery Branch Clinical Research Protocols are currently recruiting for multiple cancer studies, including synovial sarcoma, melanoma,…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Immediate Lymphatic Reconstruction After Lymphadenectomy in Melanoma Patients: a Parallel Cohort Pilot Study [NA]
A pilot parallel-cohort clinical trial evaluating immediate lymphatic reconstruction after lymphadenectomy in melanoma patients; the study i…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Natural History Study of Early Life Exposures in Agriculture (ELEA)
An update on the ELEA natural history study sponsored by the National Cancer Institute investigating how early life exposures in agriculture…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies [Phase 2]
Phase 2 clinical trial evaluating a PD-1–blocking monoclonal antibody in combination with a metabolic modulator for several solid tumors is …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study of DXC014 in Patients With Advanced Solid Tumors. [Phase 1]
Phase 1 study of the investigational drug DXC014 in advanced solid tumors is currently recruiting. It includes patients with small cell lung…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Intratumoral Targeted Hyperthermia Therapy (THT) for Cutaneous Metastatic Melanoma [NA]
A clinical trial update for Intratumoral Targeted Hyperthermia Therapy (THT) in cutaneous metastatic melanoma, currently not yet recruiting …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Clinical Genetics Branch Eligibility Screening Survey
National Cancer Institute conducts an eligibility screening survey for a clinical trial spanning multiple cancer predisposition conditions, …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A PK Study to Compare GME751 (Proposed Pembrolizumab Biosimilar) and US-licensed and EU-authorized Keytruda® in Participants With Stage II and III Melanoma [Phase 1]
A phase 1 PK study comparing GME751, a proposed pembrolizumab biosimilar by Sandoz, to Keytruda in participants with stage II-III melanoma; …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Phase II Study of Neoadjuvant Pembrolizumab & Lenvatinib for Resectable Stage III Melanoma [Phase 2]
A Phase II trial evaluating neoadjuvant pembrolizumab plus lenvatinib in patients with resectable stage III melanoma; the study is currently…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
AstraZeneca is conducting a Phase 1/2 trial to evaluate the safety of AZD6750 in adults with select advanced or metastatic solid tumors; the…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations. [Phase 1]
Pfizer's PF-07799933 is being studied in a Phase 1 trial for advanced solid tumors with BRAF alterations. The study includes melanoma, non-s…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma [Phase 2]
This entry notes a phase 2 clinical trial evaluating fianlimab, cemiplimab, and ipilimumab in advanced melanoma and indicates the trial is c…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors [Phase 1]
Pfizer is conducting a Phase 1 study of PF-07799544 as a monotherapy or in combination for advanced solid tumors, including melanoma and gli…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: MElanoma Research Lymph Node Prediction Implementation National_001
This document updates an ongoing nationwide melanoma study focused on implementing lymph node prediction, with the trial currently active bu…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma [Phase 2, Phase 3]
A clinical trial update announces a Phase 2/Phase 3 study of LNS8801 with or without pembrolizumab in patients with refractory melanoma, and…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: ctDNA-guided Addition of Ipilimumab to Patients Receiving Nivolumab and Relatlimab [Phase 4]
Phase 4 study evaluating ctDNA-guided addition of ipilimumab to patients receiving nivolumab and relatlimab for metastatic or advanced melan…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ezabenlimab [Phase 1]
A Phase 1 clinical trial evaluating how BI 765063 and BI 770371 are taken up in tumors of patients with advanced cancers who are receiving e…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Follow Up Protocol for Subjects Previously Enrolled on NCI Surgery Branch Studies
The document provides an update to the follow-up protocol for subjects previously enrolled in NCI Surgery Branch studies. It covers follow-u…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Melanoma [Phase 2]
This document provides a status update on a Phase 2 trial evaluating lifileucel (tumor-infiltrating lymphocytes) in adults with advanced mel…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors [Phase 1]
A Phase 1 study evaluating the safety and potential early efficacy of NST-628 oral tablets in adults with solid tumors is currently recruiti…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Dabrafenib and/or Trametinib Rollover Study [Phase 4]
Phase 4 rollover study of dabrafenib and/or trametinib for melanoma and non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord [Phase 2]
This is a Phase 2 clinical trial update evaluating the combination of thermal ablation and spine stereotactic radiosurgery for spine metasta…