Medulloblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-18Clinical Trial Results: Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers [Phase 2]
Phase 2 trial of nivolumab for recurrent rare CNS cancers (including medulloblastoma and ependymoma) was terminated with results posted in 2…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
An exploratory study evaluating the effects of radiation therapy in pediatric patients with central nervous system tumors; the study include…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) [Phase 2]
Phase 2 update from the Pediatric MATCH trial describes targeted therapies matched to tumor genetics in pediatric patients with relapsed or …
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors [Phase 1]
Phase 1 clinical trial evaluating B7-H3–specific CAR T cell therapy delivered locoregionally for diffuse intrinsic pontine glioma/diffuse mi…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma [Phase 1]
This clinical trial update describes a Phase 1 study evaluating a combination of adoptive T cell therapy, dendritic cell vaccines, and hemat…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating IDH1-mutant tumors for response to ivosidenib; results for recurrent and refractory solid tumors, l…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Rare CNS Tumors Outcomes &Risk
A National Cancer Institute clinical trial update reports outcomes and risks for rare central nervous system tumors, including meningioma, e…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Digoxin Medulloblastoma Study [Phase 2]
Phase 2 clinical trial evaluating digoxin for medulloblastoma is currently recruiting at H. Lee Moffitt Cancer Center; the study targets Med…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: An Intermediate Expanded Use Trial of DFMO
This is an update on an intermediate expanded-use trial of DFMO for neuroblastoma and several embryonal CNS tumors, including medulloblastom…
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors [Phase 4]
Phase 4 HeadStart4 trial for newly diagnosed children under 10 with medulloblastoma and other CNS embryonal tumors. The study status is ACTI…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Components of Social Functioning in Survivors of Pediatric Brain Tumors
This clinical trial update reports on social functioning components in survivors of pediatric brain tumors, including medulloblastoma, and n…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: B7-H3.CD28Z.CART in CNS Neoplasms [Phase 1]
A Phase 1 clinical trial evaluating B7-H3.CD28Z.CART for central nervous system neoplasms is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG [Phase 2]
Phase 2 pediatric trial evaluating indoximod with chemotherapy and radiation for relapsed brain tumors or newly diagnosed diffuse intrinsic …
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors [Phase 1]
Phase 1 trial evaluating locoregional EGFR806-specific CAR T cells for EGFR-positive pediatric CNS tumors. The study status is completed.
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
This update reports on a Phase 2 pediatric MATCH trial evaluating selpercatinib for patients with activating RET gene alterations across adv…
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery [Phase 1, Phase 2]
This terminated Phase 1/2 trial assessed the safety and tolerability of CX-4945 (silmitasertib) in pediatric patients with recurrent medullo…
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: Personalized Risk-Adapted Therapy in Post-Pubertal Patients With Newly-Diagnosed Medulloblastoma [Phase 2]
A Phase 2 trial evaluating personalized risk-adapted therapy in post-pubertal patients with newly diagnosed medulloblastoma was terminated.
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating larotrectinib in patients with NTRK gene fusions has posted results; the study remains active but n…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Pharmacoscopy for Patients With Refractory Primary Brain Tumors [Phase 2]
Phase 2 clinical trial update for pharmacoscopy in patients with refractory primary brain tumors, currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Hyperfractionated Versus Conventionally Fractionated Radiotherapy in Standard Risk Medulloblastoma (PNET4) [Phase 3]
This Phase 3 clinical trial comparing hyperfractionated radiotherapy to conventionally fractionated radiotherapy in standard-risk medullobla…
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma [NA]
A clinical trial evaluating proton beam radiotherapy for medulloblastoma and pineoblastoma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma [Phase 3]
Phase 3 clinical trial evaluating metformin for brain repair in children who previously received cranial-spinal radiation for medulloblastom…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers [Phase 2]
A Phase 2 trial of nivolumab in patients with recurrent select rare CNS cancers (medulloblastoma, ependymoma, pineal region tumors, choroid …
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
Phase 2 pediatric MATCH trial results for Tipifarnib in HRAS-altered solid tumors and histiocytic disorders; the study has posted results an…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors [Phase 1]
Volitinib is being studied in a Phase 1 trial for patients with recurrent or refractory primary CNS tumors, with the study currently listed …