Clinical Trial Update: Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors [Phase 1]

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Summary

Phase 1 clinical trial evaluating B7-H3–specific CAR T cell therapy delivered locoregionally for diffuse intrinsic pontine glioma/diffuse midline glioma and rec…

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Diseases / indications

• Atypical Teratoid Rhabdoid Tumor
• Choroid Plexus Carcinoma
• Diffuse Intrinsic Pontine Glioma
• Diffuse Midline Glioma
• Ependymoma
• Germ Cell Tumor
• Medulloblastoma
• Pineoblastoma

Drugs mentioned

• B7-H3 CAR T cell therapy

Snippet

Sponsor: Seattle Children's Hospital | Conditions: Central Nervous System Tumor, Diffuse Intrinsic Pontine Glioma | Phase 1 | Status: RECRUITING