Medulloblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-18Clinical Trial Results: Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers [Phase 2]
Phase 2 trial of nivolumab for recurrent rare CNS cancers (including medulloblastoma and ependymoma) was terminated with results posted in 2…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Methionine PET/CT Studies In Patients With Cancer [Phase 2]
Phase 2 methionine-based PET/CT imaging studies in patients with various cancers; the trial is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
An exploratory study evaluating the effects of radiation therapy in pediatric patients with central nervous system tumors; the study include…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: CSIMEMPHIS: Long-term Follow-up of Medulloblastoma Survivors That Received Craniospinal Irradiation
A clinical trial update describing long-term follow-up of medulloblastoma survivors who received craniospinal irradiation; the study is curr…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Quantitative Assessment of Radiation-induced Neuroinflammation - A Proof of Principle Study [Phase 2]
Phase 2 clinical trial update examining quantitative measures of radiation-induced neuroinflammation in brain tumor and medulloblastoma; the…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors
This trial update describes a pediatric brain tumor study using cerebrospinal fluid cell-free tumor DNA; the study was terminated.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma [NA]
The document reports a clinical trial update for an individualized treatment plan in children and young adults with relapsed medulloblastoma…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) [Phase 2]
Phase 2 update from the Pediatric MATCH trial describes targeted therapies matched to tumor genetics in pediatric patients with relapsed or …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Lutathera (177Lu-DOTATATE) in combination with Olaparib for somatostatin receptor–expressing recurrent…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors [Phase 1]
Phase 1 clinical trial evaluating B7-H3–specific CAR T cell therapy delivered locoregionally for diffuse intrinsic pontine glioma/diffuse mi…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Lutathera (lutetium-177 dotatate) for recurrent or progressive high-grade central nervous system tumor…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors [Phase 1]
Phase 1 trial updating the investigation of HSV-1 G207 for children with recurrent or refractory cerebellar brain tumors; the study is curre…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial) [Phase 2]
This update reports on a Phase 2 pediatric MATCH trial evaluating ensartinib for patients with relapsed or refractory ALK- or ROS1-genomic a…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study
This registry study collects data on relapsed and progressive medulloblastoma driven by Sonic Hedgehog (SHH) pathway activation, including t…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma [Phase 1]
Phase 1 trial of pembrolizumab in pediatric patients with recurrent or refractory high-grade gliomas, including diffuse intrinsic pontine gl…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults [NA]
Overview of the my.naviGATE guide for after-treatment effects in adolescents and young adults with sarcoma and related cancers; the study is…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma [Phase 2]
Phase 2 clinical trial of the PEP-CMV CMV antigen-targeted vaccine for newly diagnosed pediatric high-grade glioma, diffuse intrinsic pontin…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma [Phase 1]
A Phase 1 pediatric trial of SurVaxM for progressive or relapsed medulloblastoma, high-grade glioma, ependymoma, and newly diagnosed diffuse…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma [Phase 1]
This clinical trial update describes a Phase 1 study evaluating a combination of adoptive T cell therapy, dendritic cell vaccines, and hemat…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating IDH1-mutant tumors for response to ivosidenib; results for recurrent and refractory solid tumors, l…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB) [Phase 1]
Phase 1 clinical trial evaluating RNA-lipid particle vaccines for recurrent or progressive medulloblastoma; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Rare CNS Tumors Outcomes &Risk
A National Cancer Institute clinical trial update reports outcomes and risks for rare central nervous system tumors, including meningioma, e…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications [Phase 1, Phase 2]
Clinical trial update for PLX038 in primary CNS tumors with MYC or MYCN amplification; Phase 1/2 studies are currently recruiting.
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) [Phase 1]
This clinical trial update describes an ongoing Phase 1 study evaluating adoptive cellular therapy immunotherapy for several pediatric malig…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma [Phase 1, Phase 2]
This clinical trial update describes a phase 1/2 study of PEP-CMV in combination with nivolumab for newly diagnosed and recurrent diffuse mi…