Malignant Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2014-01-10Clinical Trial Update: Radiation Therapy, Temozolomide, Tamoxifen, and Carboplatin in Treating Patients With Malignant Gliomas [Phase 2]
Phase 2 clinical trial evaluating a combination of radiation therapy, temozolomide, tamoxifen, and carboplatin for malignant gliomas; curren…
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CLINICAL_TRIALS trial_result · 2014-01-06Clinical Trial Update: Temozolomide in Treating Patients With Recurrent or Progressive Malignant Glioma [Phase 2]
A Phase 2 clinical trial update on temozolomide for patients with recurrent or progressive malignant glioma.
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CLINICAL_TRIALS trial_result · 2013-12-18Clinical Trial Update: Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignant Glioma [Phase 3]
A Phase 3 trial comparing temozolomide to the PCV regimen (procarbazine, lomustine, and vincristine) in patients with recurrent malignant gl…
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CLINICAL_TRIALS trial_result · 2013-12-16Clinical Trial Update: Nuvigil or Placebo in Newly Diagnosed Malignant Glioma [Phase 2]
A Phase 2 randomized trial of Nuvigil (armodafinil) versus placebo in newly diagnosed malignant glioma was terminated. Results were posted i…
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CLINICAL_TRIALS research · 2013-11-06Clinical Trial Update: Carmustine Followed By Surgery in Treating Patients With Recurrent Supratentorial Malignant Glioma or Metastatic Brain Neoplasm [Phase 1, Phase 2]
This ClinicalTrials.gov update describes a phase 1/2 study evaluating Carmustine followed by surgery in patients with recurrent supratentori…
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CLINICAL_TRIALS research · 2013-11-06Clinical Trial Update: Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas [Phase 3]
This is a Phase 3 trial evaluating whether adding photodynamic therapy to standard surgery, radiation therapy, and chemotherapy improves tre…
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CLINICAL_TRIALS trial_result · 2013-10-30Clinical Trial Update: Study of NPC-08 is to Treat for Newly-Diagnosed Malignant Glioma and Recurrent Glioblastoma Multiforme [Phase 1, Phase 2]
Clinical trial update showing completion of Phase 1 and Phase 2 studies of NPC-08 for newly diagnosed malignant glioma and recurrent gliobla…
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CLINICAL_TRIALS trial_result · 2013-09-17Clinical Trial Update: Cisplatin and Temozolomide in Treating Young Patients With Malignant Glioma [Phase 2]
Phase 2 trial update of cisplatin and temozolomide in treating young patients with malignant glioma.
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CLINICAL_TRIALS trial_result · 2013-09-04Clinical Trial Update: Bevacizumab Plus Irinotecan Plus Carboplatin for Recurrent Malignant Glioma (MG) [Phase 2]
Phase 2 trial evaluating bevacizumab in combination with irinotecan and carboplatin for recurrent malignant glioma; results have been posted…
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CLINICAL_TRIALS trial_result · 2013-09-04Clinical Trial Update: Panitumumab and Irinotecan for Malignant Gliomas [Phase 2]
Phase 2 trial evaluating panitumumab in combination with irinotecan for malignant glioma was terminated with results posted in 2013.
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FDA approval · 2013-08-16FDA Approved: GLIADEL — Supplemental Application (Azurity Pharmaceuticals, Inc.)
FDA approved a supplemental application for GLIADEL (carmustine) by Azurity Pharmaceuticals, Inc. The approval updates the product’s labelin…
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CLINICAL_TRIALS trial_result · 2013-07-18Clinical Trial Update: Gimatecan in Treating Patients With Recurrent or Progressive Primary Malignant Glioma [Phase 1, Phase 2]
Phase 1/2 clinical trial results are reported for gimatecan in patients with recurrent or progressive primary malignant glioma. The study ha…
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CLINICAL_TRIALS trial_result · 2013-06-26Clinical Trial Update: Immunotoxin Therapy Before and After Surgery in Treating Patients With Recurrent Malignant Glioma [Phase 1]
Phase 1 trial evaluating immunotoxin therapy before and after surgery for recurrent malignant glioma has completed.
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CLINICAL_TRIALS trial_result · 2013-06-26Clinical Trial Update: Dose Escalation Study of Vandetanib With Hypofractionated Stereotactic Radiotherapy in Recurrent Malignant Gliomas [Phase 1]
A Phase 1 dose-escalation trial evaluating vandetanib with hypofractionated stereotactic radiotherapy for recurrent malignant gliomas has co…
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CLINICAL_TRIALS trial_result · 2013-06-26Clinical Trial Update: Internal Radiation Therapy Plus Carmustine Implants in Treating Patients With Recurrent or Refractory Malignant Glioma [Phase 1]
This clinical trial update reports completion of a Phase 1 study evaluating internal radiation therapy combined with carmustine implants for…
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CLINICAL_TRIALS trial_result · 2013-06-25Clinical Trial Update: ADV-TK Improves Outcome of Recurrent High-Grade Glioma [Phase 2]
Phase 2 trial of ADV-TK in recurrent high-grade glioma reports improved outcomes in malignant glioma and glioblastoma. The study is complete…
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CLINICAL_TRIALS trial_result · 2013-06-25Clinical Trial Update: Sunitinib to Treat Recurrent Brain Cancer [Phase 2]
A Phase 2 trial of sunitinib for recurrent brain cancer (glioblastoma, malignant glioma, and anaplastic glioma) was terminated with results …
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CLINICAL_TRIALS trial_result · 2013-06-24Clinical Trial Update: Immunotoxin Therapy in Treating Patients With Malignant Glioma [Phase 1, Phase 2]
A completed phase 1/2 clinical trial evaluating immunotoxin therapy for malignant glioma.
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CLINICAL_TRIALS trial_result · 2013-06-21Clinical Trial Update: Efaproxiral Plus Carmustine in Treating Patients With Progressive or Recurrent Malignant Glioma [Phase 1, Phase 2]
Clinical trial evaluating the combination of efaproxiral and carmustine for progressive or recurrent malignant glioma has completed Phase 1 …
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CLINICAL_TRIALS research · 2013-06-21Clinical Trial Update: Irinotecan in Treating Patients With Recurrent Malignant Glioma [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating irinotecan in patients with recurrent malignant glioma.
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CLINICAL_TRIALS trial_result · 2013-06-20Clinical Trial Update: Irinotecan Plus Carmustine in Treating Patients With Recurrent Primary Malignant Glioma [Phase 1]
A Phase 1 clinical trial evaluating the combination of irinotecan and carmustine for patients with recurrent primary malignant glioma has be…
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CLINICAL_TRIALS trial_result · 2013-06-19Clinical Trial Update: Temozolomide in Treating Patients With Recurrent Malignant Glioma [Phase 2]
This document provides an update on a Phase 2 trial of temozolomide for patients with recurrent malignant glioma and notes that the study st…
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CLINICAL_TRIALS trial_result · 2013-04-22Clinical Trial Update: Bevacizumab in Combination With Metronomic Temozolomide for Recurrent Malignant Glioma [Phase 2]
Phase 2 trial update reporting results for bevacizumab in combination with metronomic temozolomide in recurrent malignant glioma, including …
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CLINICAL_TRIALS trial_result · 2013-04-10Clinical Trial Update: A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomas [Phase 1]
A completed Phase 1 study evaluating XL765 in combination with temozolomide with or without radiation in adults with malignant gliomas.
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CLINICAL_TRIALS trial_result · 2013-04-04Clinical Trial Update: Combination Chemotherapy Following Radiation Therapy in Treating Patients With Malignant Glioma [Phase 1]
A Phase 1 trial evaluated combination chemotherapy following radiation therapy for malignant glioma; the study has completed.