Malignant Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: Low Dose Naltrexone for Glioma Patients [Phase 2]
Phase 2 study evaluating low-dose naltrexone in malignant glioma has completed and results are posted.
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FDA approval · 2015-06-01FDA Approved: GLIADEL — Supplemental Application (Azurity Pharmaceuticals, Inc.)
FDA approved a supplemental application for GLIADEL (carmustine) filed by Azurity Pharmaceuticals, Inc.
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Chemotherapy Followed by Radiation Therapy in Treating Patients With Malignant Glioma [Phase 1]
A Phase 1 trial evaluating chemotherapy followed by radiation therapy for malignant glioma has completed.
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CLINICAL_TRIALS trial_result · 2015-04-27Clinical Trial Update: A Phase II Study to Treat Advanced Malignant Glioma [Phase 2]
A Phase II clinical trial sponsored by Amgen evaluating a treatment for advanced malignant glioma has completed.
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FDA approval · 2015-04-02FDA Approved: TEMODAR — Supplemental Application (Merck Sharp & Dohme LLC)
FDA approves a supplemental application for TEMODAR (temozolomide) submitted by Merck Sharp & Dohme LLC.
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FDA approval · 2015-04-02FDA Approved: TEMODAR — Supplemental Application (Merck Sharp & Dohme LLC)
The FDA approved a supplemental application for Temodar (temozolomide) from Merck, resulting in an updated labeling and/or indication for th…
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CLINICAL_TRIALS trial_result · 2015-01-22Clinical Trial Update: An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma. [Phase 1, Phase 2]
This Clinical Trial Update reports the completion of an open-label Phase I/IIa dose-escalation study of 2B3-101 in patients with solid tumor…
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: CAR T Cells in Treating Patients With Malignant Gliomas Overexpressing EGFR [Phase 1]
A Phase 1 clinical trial is evaluating CAR T cells targeting EGFR in patients with malignant gliomas, including advanced glioma.
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FDA approval · 2014-11-20FDA Approved: GLIADEL — Supplemental Application (Azurity Pharmaceuticals, Inc.)
The FDA approved a supplemental application for GLIADEL (carmustine wafer) from Azurity Pharmaceuticals, Inc., to modify/expand its labeling…
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma [Phase 1, Phase 2]
The clinical trial evaluating interstitial infusion of IL13-PE38QQR cytotoxin in recurrent malignant glioma has completed Phase 1 and Phase …
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CLINICAL_TRIALS withdrawal · 2014-11-13Clinical Trial Update: Phase I/II Trial of Intracerebral IL13-PE38QQR Infusions in Pediatric Patients With Recurrent Malignant Glioma [Phase 1, Phase 2]
A Phase I/II trial of intracerebral IL-13-PE38QQR infusions in pediatric patients with recurrent malignant glioma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: The Safety and Efficacy of DCA for the Treatment of Brain Cancer [Phase 2]
This Phase 2 trial update reports safety and efficacy data for dichloroacetate (DCA) in treating malignant gliomas, including glioblastoma m…
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CLINICAL_TRIALS trial_result · 2014-10-02Clinical Trial Update: Safety and Efficacy Study of REOLYSIN® in the Treatment of Recurrent Malignant Gliomas [Phase 1]
This update presents Phase 1 results from a study of REOLYSIN in patients with recurrent malignant glioma. The trial evaluates safety and pr…
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CLINICAL_TRIALS withdrawal · 2014-09-22Clinical Trial Update: Patient Satisfaction, Efficacy and Compliance of Antiemetic Patch vs Pill in Malignant Glioma Patients [Phase 2]
The Phase 2 trial evaluating patient satisfaction, efficacy and compliance of an antiemetic patch versus an oral pill in malignant glioma pa…
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CLINICAL_TRIALS trial_result · 2014-09-15Clinical Trial Update: Imaging Study of Glioblastomas Treated With Avastin [NA]
This terminated imaging study evaluated glioblastoma patients treated with Avastin (bevacizumab); results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Malignant Glioma [Phase 1]
Phase 1 open-label dose-escalation study of ANG1005 in patients with malignant glioma.
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CLINICAL_TRIALS trial_result · 2014-07-22Clinical Trial Update: Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) With Bevacizumab and Irinotecan for Malignant Glioma [Phase 2]
Phase 2 trial evaluating Dynamic Contrast-Enhanced MRI in combination with Bevacizumab and Irinotecan for malignant glioma has completed.
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CLINICAL_TRIALS trial_result · 2014-05-30Clinical Trial Update: Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma [Phase 1]
Phase 1 clinical trial assessing aflibercept in combination with radiation therapy and temozolomide in adults with newly diagnosed or recurr…
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CLINICAL_TRIALS trial_result · 2014-05-30Clinical Trial Update: Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma [Phase 1]
This update covers a Phase 1 trial of sorafenib in patients with recurrent or progressive malignant glioma, including several glioma subtype…
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CLINICAL_TRIALS trial_result · 2014-05-22Clinical Trial Update: MRI-Guided Laser Induced Thermal Therapy
A terminated clinical trial evaluating MRI-guided laser-induced thermal therapy for malignant glioma.
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CLINICAL_TRIALS trial_result · 2014-04-01Clinical Trial Update: Intravenous Palonosetron With Radiotherapy and Concomitant Temozolomide [Phase 2]
Phase 2 trial update evaluating intravenous palonosetron with radiotherapy and temozolomide in malignant glioma has completed with results p…
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CLINICAL_TRIALS trial_result · 2014-04-01Clinical Trial Update: Aloxi for Prevention of Chemotherapy Induced Nausea and Vomiting in Malignant Glioma Patients Receiving Irinotecan With Bevacizumab [Phase 2]
A phase 2 trial of Aloxi (palonosetron) for preventing chemotherapy-induced nausea and vomiting in malignant glioma patients receiving irino…
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: Treatment Response and Prognosis in Glioma Patients: Q Cell and Its Biological Characteristics
An update on a clinical trial evaluating Q Cell in glioma patients, focusing on treatment response and prognosis.
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CLINICAL_TRIALS trial_result · 2014-01-24Clinical Trial Update: BIBW 2992 (Afatinib) With or Without Daily Temozolomide in the Treatment of Patients With Recurrent Malignant Glioma [Phase 2]
Phase 2 study evaluating afatinib (BIBW 2992) with or without daily temozolomide in patients with recurrent malignant glioma; results have b…
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CLINICAL_TRIALS trial_result · 2014-01-13Clinical Trial Update: Presurgery Bortezomib for Recurrent Malignant Gliomas Followed by Postop Bortezomib & Temozolomide [Phase 2]
Phase 2 trial evaluating presurgical bortezomib followed by postoperative bortezomib and temozolomide for recurrent malignant gliomas; resul…