Malignant Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma [Phase 1]
A Phase 1 clinical trial is evaluating the combination of acetazolamide with temozolomide in adults with newly diagnosed or recurrent malign…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma [Phase 1]
A Phase 1 clinical trial evaluating dual-targeting CAR-NK cells for recurrent/progressive glioblastoma and high-grade gliomas is currently r…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Window of Opportunity Study of DSP-0390 in Gliomas [EARLY_Phase 1]
An early-phase 1 window-of-opportunity trial of DSP-0390 in malignant gliomas with IDH mutation is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Non-invasive Glioma Characterization Through Molecular Imaging [NA]
This clinical trial update describes a study evaluating non-invasive molecular imaging to characterize gliomas and other brain tumors. It is…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Chronic CED of TPT for Recurrent Malignant Glioma [Phase 1]
Phase 1 trial evaluating chronic convection-enhanced delivery of TPT for recurrent malignant glioma is currently recruiting. The study lists…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Lutathera (lutetium-177 dotatate) for recurrent or progressive high-grade central nervous system tumor…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma [Phase 2]
A Phase 2 clinical trial update examining the combination of dabrafenib and trametinib after radiation therapy for newly diagnosed high-grad…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma [Phase 1]
Phase 1 trial of pembrolizumab in pediatric patients with recurrent or refractory high-grade gliomas, including diffuse intrinsic pontine gl…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Pilot Study Using 18F-DOPA PET-guided Radiotherapy in Gliomas
A Mayo Clinic-sponsored pilot trial evaluating 18F-DOPA PET-guided radiotherapy for malignant glioma.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: IL13Rα2 CAR-T Cells Secreting Anti-PD-L1 Antibody for Recurrent Malignant Glioma [Phase 1]
This is a Phase 1 clinical trial evaluating IL13Rα2 CAR-T cells that secrete anti-PD-L1 antibody for recurrent malignant glioma; the study i…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma [Phase 1]
Phase 1 clinical trial evaluating dual-targeting CAR-NK cells for recurrent or progressive glioblastoma and high-grade glioma is currently r…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas [Phase 1]
A Phase 1 clinical trial evaluating the combination of BGB-290 with temozolomide in patients with IDH1/IDH2-mutant gliomas, including gliobl…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma [Phase 1]
A Phase 1 trial evaluating the addition of AZD1390 to radiation therapy for newly diagnosed pediatric high-grade gliomas, including diffuse …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma [Phase 1]
Phase 1 trial evaluating mesenchymal stem cell-delivered DNX-2401 for recurrent high-grade glioma. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: CUE-102 in Recurrent Glioblastoma [Phase 1]
Phase 1 clinical trial update for CUE-102 in recurrent glioblastoma showing the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 [Phase 1]
Phase 1 clinical trial update on rQNestin34.5v.2 for recurrent malignant glioma, including glioblastoma and related gliomas, with status cur…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype [NA]
Clinical trial update: pembrolizumab is being studied in patients with hypermutator phenotype recurrent malignant glioma; the trial is curre…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas [NA]
Clinical trial investigating T2* MRI imaging and blood biomarker testing to predict changes and progression in malignant glioma. The study i…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Mind-Body Intervention in Glioma Couples [NA]
Clinical trial update for a mind-body intervention targeting glioma patients and their partners. The study is currently active but not recru…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial [Phase 2]
A Phase 2 trial (PODS) is evaluating post-operative dosing of dexamethasone in brain tumor patients after craniotomy; the study is currently…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Niraparib In Recurrent IDH 1/2 Gliomas [EARLY_Phase 1]
An early-phase 1 trial update evaluating niraparib in recurrent IDH1/2-mutant gliomas, including low-grade and malignant gliomas.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: 5G-PEARL: Paxalisib in Malignant Brain Tumours [Phase 1, Phase 2]
This update describes a Phase 1/2 clinical trial (5G-PEARL) evaluating paxalisib in malignant brain tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: CARv3-TEAM-E T Cells in Glioblastoma [Phase 1]
A Phase 1 clinical trial evaluating CARv3-TEAM-E T cells for glioblastoma and malignant glioma is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Mapping of Electrical Properties in the Brain
A Mayo Clinic-led clinical trial is recruiting to map the electrical properties of the brain in patients with malignant glioma.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: An Integrated Radio-immunological Approach
This clinical trial update indicates that the study 'An Integrated Radio-immunological Approach' (NCT05267509), sponsored by Istituto Oncolo…