Malignant Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-03-28Clinical Trial Update: Imatinib Mesylate and Temozolomide in Treating Patients With Malignant Glioma [Phase 1]
A Phase 1 study evaluating imatinib mesylate in combination with temozolomide for malignant glioma has completed.
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CLINICAL_TRIALS trial_result · 2013-03-25Clinical Trial Update: Study of Capecitabine to Treat Recurrent High Grade Gliomas [Phase 2]
Phase 2 trial evaluating capecitabine for recurrent high-grade gliomas has completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: Surgical Resection With Gliadel Wafer Followed by Dendritic Cells Vaccination for Malignant Glioma Patients [Phase 1]
A Phase 1 trial evaluated combining surgical resection with Gliadel wafer implantation followed by dendritic cell vaccination in malignant g…
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: Chemotherapy in Treating Patients With Recurrent Malignant Glioma [Phase 1]
A Phase 1 chemotherapy trial in patients with recurrent malignant glioma has completed. The update provides the trial status.
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CLINICAL_TRIALS trial_result · 2013-02-04Clinical Trial Update: Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma [Phase 2]
This is a Phase 2 clinical trial update reporting the completion of a study evaluating thiotepa followed by peripheral stem cell or bone mar…
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CLINICAL_TRIALS trial_result · 2013-02-04Clinical Trial Update: A Study of Gliadel Followed by Avastin + Irinotecan for Glioblastoma Multiforme (GBM) [Phase 2]
A phase 2 trial evaluating Gliadel implants followed by bevacizumab (Avastin) and irinotecan for glioblastoma multiforme was terminated, wit…
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma [Phase 2]
Phase 2 clinical trial evaluating Avastin with radiation and temozolomide, followed by Avastin/temozolomide/topotecan in glioblastoma patien…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma [Phase 2]
Phase 2 clinical trial evaluating zoledronate to prevent osteoporosis in patients with primary malignant glioma; the study has completed and…
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CLINICAL_TRIALS trial_result · 2012-11-30Clinical Trial Update: Tumor DNA and MRI/CT Scan Findings in Patients With Grade III or Grade IV Malignant Glioma [NA]
This completed clinical trial update reports on tumor DNA and MRI/CT imaging findings in patients with grade III or grade IV malignant gliom…
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CLINICAL_TRIALS trial_result · 2012-06-08Clinical Trial Update: Bevacizumab for Recurrent Malignant Glioma [Phase 2]
A Phase 2 trial evaluating bevacizumab for recurrent malignant glioma reported results (posted in 2012).
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CLINICAL_TRIALS trial_result · 2012-05-09Clinical Trial Update: Radiosurgery and Avastin for Recurrent Malignant Gliomas [NA]
Completed clinical trial evaluating radiosurgery combined with bevacizumab (Avastin) for recurrent malignant gliomas; results posted in 2012…
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CLINICAL_TRIALS trial_result · 2012-05-02Clinical Trial Update: ATN-161 and Carboplatin in Treating Patients With Recurrent Malignant Glioma [Phase 1, Phase 2]
Phase 1/2 trial evaluating ATN-161 in combination with carboplatin for recurrent malignant glioma has completed.
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CLINICAL_TRIALS trial_result · 2012-05-01Clinical Trial Update: A Pilot Study of Using Video Images in Advance Care Planning in Malignant Glioma Patients [NA]
A pilot study conducted by Massachusetts General Hospital evaluated the use of video images in advance care planning for patients with malig…
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CLINICAL_TRIALS trial_result · 2012-04-27Clinical Trial Update: Study of NPC-07 for Fluorescence-guided Resection of Malignant Gliomas [Phase 3]
Clinical trial update indicating completion of a Phase 3 study of NPC-07 for fluorescence-guided resection of malignant gliomas.
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CLINICAL_TRIALS trial_result · 2012-04-26Clinical Trial Update: Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid [Phase 3]
Phase 3 trial update for fluorescence-guided resection of malignant gliomas using 5-aminolevulinic acid has completed.
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CLINICAL_TRIALS withdrawal · 2012-02-22Clinical Trial Update: Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas [Phase 3]
A Phase 3 trial assessing procarbazine with isotretinoin for recurrent primary malignant gliomas has been withdrawn.
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CLINICAL_TRIALS trial_result · 2011-08-26Clinical Trial Update: VNP40101M and Temozolomide in Treating Patients With Progressive or Relapsed Malignant Glioma [Phase 1]
Phase 1 trial evaluating VNP40101M with temozolomide in progressive or relapsed malignant glioma has been terminated.
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CLINICAL_TRIALS trial_result · 2011-08-02Clinical Trial Update: Avastin / Irinotecan in Patients With Recurrent or Progressive Malignant Glioma [Phase 2]
Phase 2 trial update on bevacizumab (Avastin) in combination with irinotecan for recurrent malignant glioma. The current trial status is lis…
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CLINICAL_TRIALS trial_result · 2011-06-20Clinical Trial Update: Pazopanib In Combination With Lapatinib In Adult Patients With Relapsed Malignant Glioma [Phase 2]
Phase 2 trial evaluating pazopanib in combination with lapatinib in adults with relapsed malignant glioma; the study is completed and result…
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CLINICAL_TRIALS trial_result · 2011-06-06Clinical Trial Update: Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma [Phase 1, Phase 2]
This clinical trial update reports completion of a Phase 1/2 study evaluating IL13-PE38QQR as a pre-operative therapy in patients with recur…
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CLINICAL_TRIALS trial_result · 2011-06-06Clinical Trial Update: Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients [Phase 1]
A completed Phase 1 trial assessed histologic effects and safety of pre/post-operative IL13-PE38QQR in patients with recurrent resectable su…
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CLINICAL_TRIALS trial_result · 2011-06-06Clinical Trial Update: Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma [Phase 1]
Phase 1 imaging study evaluating how the IL13-PE38QQR conjugate distributes in adult patients with recurrent malignant glioma before and aft…
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FDA approval · 2011-06-03FDA Approved: TEMODAR — Supplemental Application (Merck Sharp & Dohme LLC)
FDA approved a supplemental application for Temodar (temozolomide) submitted by Merck Sharp & Dohme LLC.
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CLINICAL_TRIALS trial_result · 2011-01-14Clinical Trial Update: Study of Aminolevulinic Acid to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain [Phase 1]
Phase 1 trial evaluating aminolevulinic acid to enhance visualization and surgical resection of malignant glial brain tumors; the study has …
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CLINICAL_TRIALS research · 2010-12-03Clinical Trial Update: Dendritic Cell (DC) Activated Cytokine-induced Killer Cell (DCIK) Combined With DC Treatment for Glioma [Phase 1, Phase 2]
This document describes an ongoing Phase 1/Phase 2 clinical trial evaluating a combination of dendritic cell therapy with cytokine-induced k…