Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2007-11-21Clinical Trial Update: A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol. [Phase 3]
Phase 3 trial comparing torcetrapib/atorvastatin versus simvastatin in adults with high cholesterol has been completed.
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CLINICAL_TRIALS research · 2007-11-20Clinical Trial Update: Pan-European Survey on the Under Treatment of Hypercholesterolemia
An update on a pan-European survey evaluating the extent of under-treatment in patients with hypercholesterolemia.
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CLINICAL_TRIALS research · 2007-11-20Clinical Trial Update: The Anti-Diabetic and Cholesterol-Lowering Effects of Cinnamon and Cassia Bark [Phase 2]
A Phase 2 clinical trial is investigating whether cinnamon and cassia bark can improve glycemic control and lower cholesterol in people with…
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CLINICAL_TRIALS trial_result · 2007-11-16Clinical Trial Update: Efficacy and Safety of HEP-40 Chitosan for Mild to Moderately Elevated Cholesterol [Phase 2]
Phase 2 trial results evaluating the efficacy and safety of HEP-40 Chitosan in patients with hypercholesterolemia have been reported.
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CLINICAL_TRIALS trial_result · 2007-10-18Clinical Trial Update: Simvastatin Reduces Adiponectin Levels and Insulin Sensitivity
A completed clinical trial evaluated the effects of simvastatin on adiponectin levels and insulin sensitivity in patients with hypercholeste…
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CLINICAL_TRIALS trial_result · 2007-10-02Clinical Trial Update: Antioxidant Functions of Lipoic Acid [Phase 2]
A Phase 2 clinical trial evaluating the antioxidant functions of alpha-lipoic acid in hypercholesterolemia has completed recruitment and dat…
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CLINICAL_TRIALS trial_result · 2007-10-01Clinical Trial Update: Study of Oral MD-0727 Administered to Patients With Primary Hypercholesterolemia [Phase 2]
A Phase 2 clinical trial evaluating oral MD-0727 in patients with primary hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2007-09-26Clinical Trial Update: A Randomized, Double-Blind, Placebo-Controlled Study to Examine the Effect of Betahistine on Plasma Lipids in Patients Treated With Simvastatin [Phase 2]
A Phase 2 randomized, double-blind, placebo-controlled trial evaluating the effect of betahistine on plasma lipids in patients treated with …
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CLINICAL_TRIALS trial_result · 2007-09-14Clinical Trial Update: Effects of Various Higher Fat and Lower Fat Snacks on Cardiovascular Risk Factors in Men and Women. [Phase 2]
Phase 2 clinical trial evaluating the impact of higher-fat versus lower-fat snacks on cardiovascular risk factors in men and women with hype…
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CLINICAL_TRIALS trial_result · 2007-09-11Clinical Trial Update: Effect of Combination Therapy With Two Drugs (Colesevelam and Ezetimibe) in Patients With High Cholesterol [Phase 4]
A Phase 4 clinical trial evaluating the combination of Colesevelam and Ezetimibe in patients with hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2007-07-17Clinical Trial Update: Effect of the Plantago Ovata Husk on the Lipid Profile of Patients With Hypercholesterolemia [Phase 2, Phase 3]
Clinical trial update reporting on studies evaluating psyllium husk (Plantago ovata husk) for improving lipid profiles in adults with hyperc…
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CLINICAL_TRIALS trial_result · 2007-07-06Clinical Trial Update: Effect of Plant Stanols on Cholesterol Absorption [Phase 4]
Phase 4 clinical trial evaluating the effect of plant stanols on cholesterol absorption in individuals with hypercholesterolemia; the study …
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CLINICAL_TRIALS trial_result · 2007-06-13Clinical Trial Update: Pravastatin and Protease Inhibitors in HIV-Infected Patients [Phase 2]
Phase 2 trial evaluating the safety and potential lipid-lowering efficacy of pravastatin in HIV-infected patients taking protease inhibitors…
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CLINICAL_TRIALS trial_result · 2007-06-05Clinical Trial Update: Effects of Romantic Affection on Blood Chemistry and Immune Parameters [EARLY_Phase 1]
This early-phase trial from Arizona State University studied whether romantic affection affects blood chemistry and immune parameters in ind…
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CLINICAL_TRIALS trial_result · 2007-05-08Clinical Trial Update: The Effect of Strawberries in a Cholesterol-Lowering Dietary Portfolio [Phase 2]
A Phase 2 clinical trial investigated whether incorporating strawberries into a cholesterol-lowering dietary portfolio reduces cholesterol l…
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CLINICAL_TRIALS trial_result · 2007-04-18Clinical Trial Update: Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of Both [NA]
A completed clinical trial assessing the efficacy and safety of ezetimibe monotherapy, statin monotherapy, and their combination for lowerin…
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CLINICAL_TRIALS trial_result · 2007-04-06Clinical Trial Update: A Study in People With High Cholesterol [Phase 2]
Phase 2 trial in hypercholesterolemia has completed. The update does not include trial results.
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FDA approval · 2007-03-16FDA Approved: PRAVASTATIN SODIUM — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for pravastatin sodium submitted by Teva Pharmaceuticals USA, Inc. under ANDA 076056. The action rel…
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CLINICAL_TRIALS trial_result · 2007-02-26Clinical Trial Update: Study on the Safety and Effects on Lipids of FM-VP4 in Subjects With Primary Hypercholesterolemia [Phase 2]
A Phase 2 study evaluating the safety and lipid effects of FM-VP4 in adults with primary hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2007-02-12Clinical Trial Update: A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis [Phase 4]
This entry reports a Phase 4 clinical trial evaluating the effects of a lipid-lowering treatment on steroid synthesis. The current trial sta…
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FDA approval · 2007-01-16FDA Approved: LIPITOR — Supplemental Application (Viatris Specialty LLC)
The FDA approved a supplemental application for Lipitor (atorvastatin calcium) submitted by Viatris Specialty LLC.
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CLINICAL_TRIALS trial_result · 2007-01-09Clinical Trial Update: The Potential Effects and Mechanisms of Flax Lignans on Type 2 Diabetes Mellitus [Phase 2, Phase 3]
A completed Phase 2/Phase 3 clinical trial evaluating the potential effects and mechanisms of flax lignans on type 2 diabetes mellitus, with…
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FDA approval · 2006-12-20FDA Approved: SIMVASTATIN — Original Application (NorthStar Rx LLC)
The FDA approved an original application for simvastatin (generic) from NorthStar Rx LLC, making a generic version of simvastatin available.
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CLINICAL_TRIALS trial_result · 2006-11-06Clinical Trial Update: Evaluation of the Efficacy of Rosuvastatin in Daily Practice (TARGET)
A completed clinical trial evaluating the efficacy of rosuvastatin in routine daily practice for hypercholesterolemia and coronary heart dis…
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CLINICAL_TRIALS trial_result · 2006-11-01Clinical Trial Update: Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST [Phase 3]
Phase 3 dose-ranging study evaluating the safety and efficacy of a fixed-dose combination of extended-release niacin and simvastatin in adul…