Hypercholesterolemia
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CLINICAL_TRIALS trial_result · 2026-08-06Clinical Trial Results: A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids [Phase 3]
Phase 3 trial results for Enlicitide Decanoate (MK-0616), an oral PCSK9 inhibitor, in adults with hypercholesterolemia; study completed with…
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CLINICAL_TRIALS trial_result · 2026-07-17Clinical Trial Results: A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1) [Phase 2]
Phase 2 clinical trial in children aged 6 to 17 with heterozygous familial hypercholesterolemia evaluating once-daily bempedoic acid (CLEAR …
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CLINICAL_TRIALS trial_result · 2026-06-18Clinical Trial Update: A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of AG2304T and AG2304R [Phase 3]
Phase 3 clinical trial update for AG2304T and AG2304R in hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: A Clinical Study to Evaluate the Safety and Effectiveness of Inclisiran Sodium in Indian Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia [Phase 4]
Phase 4 clinical trial in India evaluating the safety and effectiveness of inclisiran sodium for primary hypercholesterolemia or mixed dysli…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Lipoprotein Metabolism in Normal Volunteers and Patients With High Levels of Lipoproteins
This completed NHLBI clinical trial evaluated lipoprotein metabolism in normal volunteers and individuals with high lipoprotein levels, prov…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Specified Drug-use Survey of Leqvio for s.c. Injection.
This clinical trial update reports a specified drug-use survey of Leqvio (inclisiran) for subcutaneous injection, with the study currently a…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world Setting
A completed non-interventional study assessing Inclisiran (Leqvio) and other lipid-lowering therapies in real-world treatment of hypercholes…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Study of Efficacy, Safety, Tolerability and Quality of Life of Inclisiran (KJX839) vs Placebo, on Top of Ongoing Individually Optimized Lipid-lowering Therapy, in Participants With Hypercholesterolemia [Phase 4]
This Phase 4 trial compares Inclisiran (KJX839) vs placebo in adults with hypercholesterolemia on ongoing lipid-lowering therapy to assess e…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Dachundou No Sugar Added Soymilk for Lipid Modulation [NA]
A completed clinical trial from National Taiwan Sport University evaluating Dachundou No Sugar Added Soymilk for lipid modulation in individ…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Efficacy of Lactobacillus Mucosae DPC6426 on Blood-lipids [NA]
A completed clinical trial evaluated the effect of the probiotic Lactobacillus mucosae DPC6426 on blood lipid levels in individuals with hyp…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular Disease
Verve Therapeutics reports long-term follow-up data from participants treated with its investigational gene-editing therapy for cardiovascul…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Pharmacokinetics of Butyrate Tablet BKR-017
The completed clinical trial provides pharmacokinetic data for the Butyrate Tablet BKR-017 in hypercholesterolemia. It summarizes absorption…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Enlicitide (MK-0616, Oral PCSK9 Inhibitor) Compared With Ezetimibe or Bempedoic Acid or Ezetimibe and Bempedoic Acid in Adults With Hypercholesterolemia (MK-0616-018/CORALreef AddOn) [Phase 3]
A Phase 3 study evaluating the efficacy and safety of Enlicitide (MK-0616) versus ezetimibe, bempedoic acid, or their combination in adults …
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: A Prospective, Open, Observational Study to Confirm the Lipid-lowering Effect, Changes in Glucose Metabolism, and Safety After 6 Months of Administration of Atostazet to Hypercholesterolemic Patients 65 Years of Age or Older
A completed prospective observational trial evaluating the lipid-lowering effect, changes in glucose metabolism, and safety of Atostazet in …
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Red Yeast Rice for Primary Prevention of Hypercholesterolemia
A clinical trial evaluating red yeast rice for primary prevention of hypercholesterolemia has completed, sponsored by Chang Gung Memorial Ho…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of DW5421A/DW5421B Compared to Monotherapy of DW5421A [Phase 3]
A Phase 3 trial evaluated the combination DW5421A/DW5421B versus DW5421A monotherapy for primary hypercholesterolemia and mixed dyslipidemia…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Efficacy and Safety of Pitavastatin/Ezetimibe After Switching From Statin Monotherapy to Pitavastatin/Ezetimibe in Patients With Hypercholesterolemia
A completed clinical trial evaluating the efficacy and safety of switching to Pitavastatin/Ezetimibe in patients with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Long-term Comparison of Pitavastatin/Ezetimibe and Pitavastatin in Patients With Hypercholesterolemia and Elevated Triglycerides [Phase 4]
Phase 4 trial comparing long-term outcomes of pitavastatin/ezetimibe versus pitavastatin alone in patients with hypercholesterolemia and ele…
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH) [Phase 3]
Phase 3 trial update for Enlicitide Decanoate (MK-0616), an oral PCSK9 inhibitor, in adults with heterozygous familial hypercholesterolemia,…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: A Long-term Trial of ETC-1002 in Patients With Hyper-LDL Cholesterolemia [Phase 3]
Phase 3 long-term trial results for ETC-1002 (bempedoic acid) in adults with hypercholesterolemia were completed, with results posted in Feb…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: A Study to Evaluate the Safety, Efficacy of SYH2053 in Chinese Participants With Non-familial Hypercholesterolemia and Mixed Hyperlipidemia [Phase 2]
A Phase 2 trial evaluating the safety and efficacy of SYH2053 in Chinese participants with non-familial hypercholesterolemia and mixed hyper…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: A Study to Assess the Real-World Effectiveness of Inclisiran and PCSK9 mAbs in Chinese Hypercholesterolemia Adult Patients
A completed real-world study assessing the effectiveness of inclisiran and PCSK9 monoclonal antibodies in Chinese adults with hypercholester…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: A Study Of SHR-1918 In Participants With Hypercholesterolemia With Inadequate Lipid Control on Statins Plus PCSK9 Inhibitors [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial update for SHR-1918 in hypercholesterolemia patients not adequately controlled on statins plus PCSK9 inhibi…
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Efficacy and Safety of Livalozet® in Hypercholesterolemic Patients With and Without Diabetes
This completed trial evaluated the efficacy and safety of Livalozet in adults with hypercholesterolemia, including participants with and wit…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease. [Phase 4]
Phase 4 trial comparing LDL-cholesterol lowering with Inclisiran versus Bempedoic acid in patients with atherosclerotic cardiovascular disea…