Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2025-06-05Clinical Trial Update: A Pilot Study to Explore the Role of Gut Flora in Elevated Cholesterol
A pilot clinical trial investigating the role of gut flora in elevated cholesterol has been withdrawn from the registry.
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CLINICAL_TRIALS withdrawal · 2025-03-06Clinical Trial Update: Impact of Cholesterol Level on Long-term Coronary Bypass Graft Patency
A clinical trial evaluating how cholesterol levels affect long-term patency of coronary artery bypass grafts has been withdrawn; the study i…
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CLINICAL_TRIALS withdrawal · 2024-12-16Clinical Trial Update: Effect of Irbesartan on Endothelial Function of the Retinal Vasculature in Patients With Hypercholesterolemia [Phase 3]
The Phase 3 trial assessing irbesartan for improving retinal endothelial function in adults with hypercholesterolemia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2022-07-28Clinical Trial Update: Evolocumab In Advanced Chronic Kidney Disease Trial [Phase 4]
A Phase 4 trial of evolocumab in advanced chronic kidney disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-06-05Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety of DP-R212 [Phase 3]
A Phase 3 clinical trial evaluating DP-R212 for hypertension and hypercholesterolemia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-04-27Clinical Trial Update: Magnetic Resonance Imaging-Portfolio Diet Study #7 [NA]
This document reports the withdrawal of Clinical Trial Update: Magnetic Resonance Imaging-Portfolio Diet Study #7, sponsored by Unity Health…
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CLINICAL_TRIALS withdrawal · 2017-04-26Clinical Trial Update: Enhanced Multicenter Dietary Portfolio Study [NA]
The Enhanced Multicenter Dietary Portfolio Study has been withdrawn. It involved conditions including cardiovascular diseases, Type 2 diabet…
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CLINICAL_TRIALS withdrawal · 2016-10-21Clinical Trial Update: Pharmacokinetic and Pharmacodynamic Study of Bococizumab Alone and When Combined With Recombinant Human Hyaluronidase [Phase 1]
Pfizer terminated a Phase 1 pharmacokinetic and pharmacodynamic study of bococizumab, both alone and with recombinant human hyaluronidase, i…
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CLINICAL_TRIALS withdrawal · 2016-09-27Clinical Trial Update: Genetic Influence on Statin Pharmacodynamics
A clinical trial investigating genetic influence on statin pharmacodynamics was withdrawn from the registry.
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CLINICAL_TRIALS withdrawal · 2015-04-23Clinical Trial Update: Multiple-Dose Safety Study Of RN316 For TheTreatment Of Hypercholesterolemia [Phase 1]
Phase 1 multiple-dose safety study of the investigational drug RN316 for hypercholesterolemia/dyslipidemia has been withdrawn.
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EMA withdrawal · 2013-06-17EMA Refused: Kynamro (mipomersen sodium) — Genzyme Europe BV
The EMA refused approval for Kynamro (mipomersen sodium) by Genzyme Europe BV for hypercholesterolemia.
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CLINICAL_TRIALS withdrawal · 2013-03-22Clinical Trial Update: Garlic in Hyperlipidemia Caused by HAART [Phase 2]
This update indicates a Phase 2 trial evaluating garlic for HAART-induced hyperlipidemia in people with HIV has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2012-05-24Clinical Trial Update: Efficacy of Lapaquistat Acetate Alone or Combined With High-Dose Statin Therapy in Subjects With Hypercholesterolemia [Phase 3]
Phase 3 trial evaluating lapaquistat acetate alone or with high-dose statin in hypercholesterolemia has been terminated.
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CLINICAL_TRIALS withdrawal · 2011-08-12Clinical Trial Update: Study of MB07811 in Subjects With Hypercholesterolemia [Phase 2]
This Phase 2 trial of MB07811 in hypercholesterolemia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2009-03-26Clinical Trial Update: ORBITAL: Open-Label Primary Care Study: Rosuvastatin Based Compliance Initiatives Linked To Achievement Of LDL Goals [Phase 4]
The ORBITAL Phase 4 trial investigating rosuvastatin-based compliance initiatives to achieve LDL goals in primary hypercholesterolemia has b…
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CLINICAL_TRIALS withdrawal · 2009-03-26Clinical Trial Update: Effect of an Internet Based Compliance Enhancement Tool in Subjects With Hypercholesterolemia [Phase 4]
A Phase 4 clinical trial evaluating an Internet-based compliance enhancement tool for people with hypercholesterolemia has been withdrawn.