Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVD [NA]
Clinical trial update describing a study of a moderate-intensity statin plus ezetimibe in patients with chronic kidney disease and atheroscl…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes [Phase 3]
Enlicitide Decanoate (MK-0616) is being studied as an oral PCSK9 inhibitor in the Phase 3 CORALreef Outcomes cardiovascular outcomes trial (…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Real-World Study of Long-Term Adherence and Persistence to Inclisiran, Evolocumab, and Alirocumab
This real-world clinical trial update reports on long-term adherence and persistence to inclisiran, evolocumab, and alirocumab among patient…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Assessing the Effects of Corn and Avocado Oils on the Cardiometabolic Risk Factor Profile [NA]
A clinical trial is evaluating the effects of corn oil and avocado oil on cardiometabolic risk factors in adults with hypercholesterolemia; …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Pharmacogenomic Informed Statin Prescribing [NA]
A clinical trial is investigating pharmacogenomic informed statin prescribing for hypercholesterolemia. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Triple vs Dual Lipid-Lowering Therapy for LDL-C Reduction in Acute Coronary Syndrome [Phase 4]
Phase 4 clinical trial comparing triple versus dual lipid-lowering therapy to reduce LDL-C in patients with acute coronary syndrome; not yet…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Evaluate the Safety, Efficacy of SYH2053 as Monotherapy in Chinese Participants With Non-familial Hypercholesterolemia or Mixed Hyperlipidemia [Phase 3]
Phase 3 clinical trial evaluating SYH2053 as monotherapy for non-familial hypercholesterolemia or mixed hyperlipidemia in Chinese participan…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of Bempedoic Acid in Combination With Ezetimibe and Either Rosuvastatin or Atorvastatin in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia
A clinical trial evaluating bempedoic acid in combination with ezetimibe and either rosuvastatin or atorvastatin in people with primary hype…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Causes and Natural History of Dyslipidemias
This clinical trial update discusses the causes and natural history of dyslipidemias, including hypercholesterolemia and atherosclerosis, sp…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study of Bempedoic Acid or Its Single-pill Combination Therapy With Ezetimibe in Patients With Primary Hypercholesterolaemia or Mixed Dyslipidaemia
This clinical trial evaluates bempedoic acid alone or in a fixed-dose single-pill combination with ezetimibe for primary hypercholesterolemi…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias [Phase 1]
The trial is a Phase 1 safety and tolerability study of CTX310 in participants with refractory dyslipidemias. It is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Mechanism of Ketogenic Diet-Induced Hypercholesterolemia [NA]
This clinical trial update from Washington University School of Medicine describes a study on the mechanism by which a ketogenic diet may in…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Real World Adherence of PCSK9 Targeted Therapy
Novartis sponsors a real-world study to evaluate adherence to a PCSK9-targeted therapy in patients with dyslipidemia and hypercholesterolemi…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia
Clinical trial update on treatment with bempedoic acid and its fixed-dose combination with ezetimibe for primary hypercholesterolemia and mi…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events [Phase 3]
Phase 3 study evaluating a combination of bempedoic acid, ezetimibe, and a high-intensity statin in patients without cardiovascular events; …
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Elevated Lipoprotein(a) in Hospital Staff
The update describes a clinical trial studying elevated lipoprotein(a) in hospital staff with hypercholesterolemia and related cardiovascula…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of weekly alirocumab in adults with hypercholesterolemia; the study is currently…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Electronic Letters to Improve Patient Activation in IHD: The NUDGE-IHD Trial [NA]
A clinical trial update for the NUDGE-IHD study investigating electronic letters to improve patient activation in ischemic heart disease; th…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: QLC7401 in the Treatment of Primary Hypercholesterolemia or Mixed Hyperlipidemia With Elevated Low Density Lipoprotein Cholesterol (LDL-C) [Phase 3]
A Phase 3 clinical trial evaluating QLC7401 for primary hypercholesterolemia or mixed hyperlipidemia with elevated LDL-C; the study is not y…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: QLC7401 Monotherapy in Non-familial Hypercholesterolemia or Mixed Dyslipidemia [Phase 3]
A Phase 3 clinical trial update for QLC7401 monotherapy in primary hypercholesterolemia or mixed dyslipidemia, sponsored by Qilu Pharmaceuti…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial [Phase 2]
A Phase 2 clinical trial titled 'Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders' is currently recruiting. The study i…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Study of STX-1150 in Participants With Elevated Low-Density Lipoprotein Cholesterol (LDL-C) [Phase 1]
This is a Phase 1 clinical trial update for STX-1150 in participants with elevated LDL cholesterol/high cholesterol, currently not recruitin…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: DNV001 Injection in Patients With Hypercholesterolemia [Phase 2]
Phase 2 trial of DNV001 Injection for primary hypercholesterolemia is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Improving Lipid Optimization Quality and Treatment Options in ASCVD [NA]
An ongoing, invitation-only clinical trial sponsored by Brigham and Women's Hospital focusing on improving lipid management for hypercholest…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Study on the Effect of the Intake of a Calcium-bicarbonate Water on Cholesterol Levels [NA]
A clinical trial is examining whether intake of calcium-bicarbonate water affects cholesterol levels in people with hypercholesterolemia; th…