Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2010-11-15Clinical Trial Update: Korean AMADEUS Study [Phase 4]
Phase 4 clinical trial update for the Korean AMADEUS study sponsored by The Catholic University of Korea, involving Diabetes Mellitus and Hy…
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CLINICAL_TRIALS trial_result · 2010-10-28Clinical Trial Update: Efavirenz to Nevirapine Switch and Low-Density Lipoprotein (LDL)-Dyslipidemia [Phase 4]
A Phase 4 trial evaluating switching from efavirenz to nevirapine in people with HIV and dyslipidemia, focusing on LDL cholesterol changes.
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CLINICAL_TRIALS trial_result · 2010-10-11Clinical Trial Update: Observational Study of Approaches to Lipid-Lowering Therapy in Russian Patients With Coronary Heart Disease <<Treat to Goal>> (Study P05464)
Observational study assessing approaches to lipid-lowering therapy in Russian patients with coronary heart disease and hypercholesterolemia;…
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CLINICAL_TRIALS trial_result · 2010-10-05Clinical Trial Update: Coadministration of Ezetimibe and Atorvastatin in Patients With Primary Hypercholesterolemia (P05456) [Phase 3]
This Phase 3 trial update reports results from coadministering ezetimibe with atorvastatin in adults with primary hypercholesterolemia. Resu…
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CLINICAL_TRIALS trial_result · 2010-10-05Clinical Trial Update: Different Metabolic Effects of Statins
Completed clinical trial investigating different metabolic effects among statins in patients with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2010-09-17Clinical Trial Update: Evaluation of the Efficacy and Safety of Rosuvastatin 5 mg Versus Pravastatin 40 mg and Atorvastatin 10 mg in Type IIa and IIb Hypercholesterolaemic Patients [Phase 4]
Phase 4 clinical trial comparing rosuvastatin 5 mg with pravastatin 40 mg and atorvastatin 10 mg in patients with Type IIa/IIb hypercholeste…
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FDA approval · 2010-09-08FDA Approved: SIMVASTATIN — Supplemental Application (NorthStar Rx LLC)
FDA approved a supplemental application for simvastatin submitted by NorthStar Rx LLC. The approval indicates an approved modification to th…
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CLINICAL_TRIALS trial_result · 2010-08-26Clinical Trial Update: Begin With The Right Patients With Dual-Inhibition Action Therapy Through Vytorin for Newly Diagnosed Dyslipidemia Patients (0653A-172)(COMPLETED) [Phase 4]
Phase 4 trial evaluating Vytorin (ezetimibe/simvastatin) for newly diagnosed dyslipidemia has completed with results posted in August 2010.
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CLINICAL_TRIALS trial_result · 2010-07-30Clinical Trial Update: (H.E.L.P.)Apheresis Therapy to Compare the Reduction of LDL (Low Density Lipoprotein) Cholesterol [NA]
Clinical trial update on apheresis therapy to reduce LDL cholesterol in hypercholesterolemia; study completed with results posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-07-13Clinical Trial Update: Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients. [Phase 3]
A Phase 3 trial evaluating metformin hydrochloride with colesevelam hydrochloride versus metformin alone in type 2 diabetes, and assessing t…
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CLINICAL_TRIALS trial_result · 2010-06-30Clinical Trial Update: Coadministration of Ezetimibe and Simvastatin in Patients With Primary Hypercholesterolemia (P05457) [Phase 3]
Phase 3 trial results for coadministration of ezetimibe with simvastatin in primary hypercholesterolemia have been posted.
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CLINICAL_TRIALS trial_result · 2010-06-28Clinical Trial Update: A Community Pharmacist-led Intervention to Improve Adherence to Lipid-lowering Treatment [NA]
A completed clinical trial evaluating a community pharmacist–led intervention to improve adherence to lipid-lowering therapy in hypercholest…
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CLINICAL_TRIALS trial_result · 2010-06-10Clinical Trial Update: Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355) [Phase 4]
Phase 4 trial comparing adding ezetimibe to ongoing statin therapy versus doubling statin dose for hypercholesterolemia; results posted in 2…
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FDA approval · 2010-06-01FDA Approved: LIVALO — Supplemental Application (Kowa Pharmaceuticals America, Inc.)
FDA approved a supplemental application for LIVALO (pitavastatin calcium) submitted by Kowa Pharmaceuticals America, Inc. The approval const…
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CLINICAL_TRIALS trial_result · 2010-05-25Clinical Trial Update: A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease (0653A-128) [Phase 3]
Phase 3 trial comparing an ezetimibe/simvastatin combination tablet to another cholesterol-lowering drug in elderly patients with hyperchole…
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CLINICAL_TRIALS trial_result · 2010-05-25Clinical Trial Update: Effects of Vytorin Versus Placebo in Subjects With Primary Hypercholesterolemia (Study P04420) [Phase 3]
Phase 3 trial comparing Vytorin to placebo in primary hypercholesterolemia completed with results posted.
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CLINICAL_TRIALS trial_result · 2010-05-20Clinical Trial Update: Effects of Atorvastatin on Blood Pressure and Urinary Albumin Excretion [NA]
This clinical trial update reports on the effects of atorvastatin on blood pressure and urinary albumin excretion in people with hypertensio…
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CLINICAL_TRIALS trial_result · 2010-04-15Clinical Trial Update: Effect of Simvastatin and Ezetimibe on Lipid and Inflammation [NA]
A completed clinical trial evaluating the effect of combining simvastatin and ezetimibe on lipid levels and inflammation in people with pred…
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CLINICAL_TRIALS trial_result · 2010-03-22Clinical Trial Update: Study of Asian Patients With Hypercholesterolaemia in the UK - Rosuvastatin 5mg Versus Atorvastatin 10mg [Phase 4]
A Phase 4 trial comparing rosuvastatin 5 mg to atorvastatin 10 mg in Asian patients with hypercholesterolemia in the UK was terminated, with…
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CLINICAL_TRIALS research · 2010-03-11Clinical Trial Update: The Effect Of Simvastatin On Bone Remodeling In Socket Of Mandibular Teeth [NA]
An update on a clinical trial studying whether simvastatin affects bone remodeling in mandibular tooth extraction sockets, sponsored by Hada…
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FDA approval · 2010-03-10FDA Approved: VYTORIN — Supplemental Application (Organon LLC)
The FDA approved a supplemental application for VYTORIN (ezetimibe/simvastatin) submitted by Organon LLC.
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CLINICAL_TRIALS trial_result · 2010-03-10Clinical Trial Update: Rye Bread Trial; Antioxidative and Cholesterol Lowering Effects [Phase 2]
A Phase 2 clinical trial conducted by the University of Helsinki examined whether rye bread has antioxidative effects and lowers cholesterol…
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CLINICAL_TRIALS trial_result · 2010-03-09Clinical Trial Update: Ezetimibe and Simvastatin in Primary Hypercholesterolemia, Diabetes Mellitus Type 2, and Coronary Heart Disease (COMPLETED) [Phase 3]
A Phase 3 trial of ezetimibe and simvastatin in primary hypercholesterolemia with type 2 diabetes and coronary heart disease has completed w…
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CLINICAL_TRIALS trial_result · 2010-03-05Clinical Trial Update: A Clinical Trial Study to Evaluate Efficacy and Safety of Atorvastatin in Korean Patients With Hypercholesterolemia [Phase 4]
A Phase 4 trial evaluated the efficacy and safety of atorvastatin in Korean patients with hypercholesterolemia; the study has completed.
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CLINICAL_TRIALS research · 2010-03-01Clinical Trial Update: The Effect of Niacin Administration on Oxidative Stress in Patients With Hypercholesterolmia, as Measured by the Use of a Novel Biomarker [Phase 3]
Phase 3 clinical trial update evaluating whether niacin affects oxidative stress in patients with hypercholesterolemia; the current status i…