Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-03-03Clinical Trial Update: Effect of Oats on Lipid Profile [NA]
This entry reports a completed clinical trial evaluating how oats affect the lipid profile in adults with mild hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2015-03-02Clinical Trial Update: MK0859 Dose-Ranging Study (0859-003) [Phase 2]
Merck's Phase 2 dose-ranging study of MK0859 (NCT00325455) for hypercholesterolemia and mixed hyperlipidemia has been terminated.
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: A Study of MK0859 in Patients With Primary Hypercholesterolemia or Mixed Hyperlipidemia (MK-0859-011)(COMPLETED) [Phase 1]
The Phase 1 study MK-0859-011 in patients with primary hypercholesterolemia or mixed hyperlipidemia has completed; this update confirms the …
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CLINICAL_TRIALS trial_result · 2015-02-09Clinical Trial Update: Tailored Communication to Reduce Cardiovascular Risk [NA]
This clinical trial update reports completed results from a Northwestern University study on tailored communication strategies to reduce car…
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: Serum Cholesterol Reduction Efficacy of Biscuit With Plant Stanol Ester [NA]
A completed clinical trial evaluated the effect of a biscuit containing plant stanol ester on serum cholesterol in individuals with dyslipid…
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: A 4-week, Randomized, Placebo-Controlled, Double-Blind, Efficacy and Safety Study of HS-25 in Adults With Primary Hypercholesterolemia [Phase 2]
The document reports the completion of a 4-week, randomized, placebo-controlled, double-blind Phase 2 trial evaluating HS-25 for efficacy an…
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Cholesterol-lowering Effects of Plant Stanol Ester [NA]
A completed clinical trial sponsored by Raisio Group evaluated the cholesterol-lowering effects of plant stanol ester.
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CLINICAL_TRIALS trial_result · 2014-12-19Clinical Trial Update: Effect of LDL-apheresis on PTX3 Plasma Levels in Hypercholesterolemic Patients
A completed clinical trial evaluating whether LDL-apheresis affects plasma PTX3 levels in patients with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2014-12-17Clinical Trial Update: A Study of the Effect of Ezetimibe on Glucose Metabolism in Type 2 Diabetics With Hypercholesterolemia (P06541) [Phase 4]
Phase 4 study evaluating the effect of ezetimibe on glucose metabolism in adults with type 2 diabetes and hypercholesterolemia; results were…
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CLINICAL_TRIALS trial_result · 2014-12-12Clinical Trial Update: Lentils as a Functional Food to Improve Glucose and Decrease Cardiovascular Risk [NA]
A completed university-sponsored trial evaluated lentils as a functional food to improve glucose control and reduce cardiovascular risk in p…
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CLINICAL_TRIALS trial_result · 2014-12-11Clinical Trial Update: Human Lipoprotein Pathophysiology - Subproject: Genetics of Familial Combined Hyperlipidemia
This clinical trial update reports the completion of a subproject on the genetics of familial combined hyperlipidemia, sponsored by the Univ…
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CLINICAL_TRIALS trial_result · 2014-12-11Clinical Trial Update: Effectiveness of a Combined Strategy to Improve Therapeutic Compliance and Degree of Control Among Patients With Hypercholesterolaemia [NA]
This clinical trial update discusses the effectiveness of a combined strategy to improve medication adherence and control of hypercholestero…
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: Soybean Based Diets and CVD Risk Factors [NA]
A completed Tufts University clinical trial evaluating soybean-based diets and cardiovascular disease risk factors in individuals with hyper…
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Vascular and Metabolic Effects of Rosuvastatin [Phase 4]
Completed Phase 4 trial assessing vascular and metabolic effects of rosuvastatin in patients with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Vascular and Metabolic Effects of Vytorin vs Simvastatin [Phase 4]
This Phase 4 trial evaluated vascular and metabolic effects of Vytorin (ezetimibe/simvastatin) versus simvastatin in patients with hyperchol…
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Vascular and Metabolic Effects of Vytorin [Phase 4]
This Phase 4 trial update discusses vascular and metabolic effects observed with Vytorin (ezetimibe/simvastatin) in patients with hyperchole…
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CLINICAL_TRIALS trial_result · 2014-09-29Clinical Trial Update: The Efficacy and Safety of a Combination Therapy of Rosuvastatin and Ezetimibe Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patients [Phase 3]
Phase 3 trial evaluating the efficacy and safety of rosuvastatin plus ezetimibe versus rosuvastatin alone in hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2014-09-26Clinical Trial Update: A Patient-Spouse Intervention for Self-Managing High Cholesterol [NA]
This trial update reports the completed results of a patient-spouse behavioral intervention aimed at helping individuals with hypercholester…
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CLINICAL_TRIALS trial_result · 2014-09-15Clinical Trial Update: Action to Control Cardiovascular Risk in Diabetes (ACCORD) [Phase 3]
Phase 3 ACCORD trial evaluating strategies to reduce cardiovascular risk in people with diabetes; results were posted in 2014. The study inv…
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CLINICAL_TRIALS trial_result · 2014-09-08Clinical Trial Update: Effect of Statins on Oxidative Stress and Endothelial Progenitor Cells [Phase 2]
A Phase 2 trial examined whether statin therapy modulates oxidative stress and endothelial progenitor cells in individuals with diabetes mel…
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CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Effect of Statins on Lipid Levels Following the First Acute Coronary Event (MK-0000-204)
This completed clinical trial evaluated the effect of statin therapy on lipid levels after a first acute coronary event; results were posted…
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CLINICAL_TRIALS trial_result · 2014-08-19Clinical Trial Update: A Study to Evaluate the Efficacy of Valsartan/Simvastatin Combinations in Patients With Both Essential Hypertension and Hypercholesterolemia [Phase 3]
Phase 3 study evaluating the efficacy of valsartan/simvastatin combinations in patients with essential hypertension and hypercholesterolemia…
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CLINICAL_TRIALS trial_result · 2014-08-15Clinical Trial Update: Effect of L. Reuteri NCIMB 30242 on Plasma Bile Acid Profile [Phase 2]
A Phase 2 trial evaluating the probiotic L. reuteri NCIMB 30242 and its impact on the plasma bile acid profile in adults with hypercholester…
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CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction [Phase 4]
Phase 4 open-label trial comparing ezetimibe, niacin, and colestipol as adjunct therapy for lipid reduction; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-07Clinical Trial Update: Effects of Nopales (Opuntia Spp.) on Lipoprotein Profile and Oxidative Stress in Moderately Hypercholesterolemic Adults [NA]
This clinical trial update reports completion of a study evaluating the effects of nopales (Opuntia spp.) on lipoprotein profile and oxidati…