Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Phytosterols, Ezetimibe, and Cholesterol Metabolism [EARLY_Phase 1]
An early Phase 1 trial update evaluating the interaction of phytosterols with ezetimibe on cholesterol metabolism. The study includes partic…
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CLINICAL_TRIALS trial_result · 2018-05-31Clinical Trial Update: A Trial to Evaluate the Efficacy of AB-Life Probiotic Product on LDL-Cholesterol Reduction in Moderate Hypercholesterolemia [NA]
A completed clinical trial evaluating the efficacy of AB-Life Probiotic Product on lowering LDL-cholesterol in adults with moderate hypercho…
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: Efficacy and Safety of Alirocumab Versus Placebo on Top of Maximally Tolerated Lipid Lowering Therapy in Patients With Hypercholesterolemia Who Have Type 1 or Type 2 Diabetes and Are Treated With Insulin (ODYSSEY DM - Insulin) [Phase 3]
Phase 3 trial update showing the efficacy and safety of alirocumab versus placebo on top of maximally tolerated lipid-lowering therapy in ad…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: The Effect of CBT- Based Weight Loss Program on Obesity [NA]
This document reports the completed status of a clinical trial evaluating a cognitive-behavioral therapy-based weight loss program for obesi…
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CLINICAL_TRIALS trial_result · 2018-05-07Clinical Trial Update: Efficacy and Safety of Alirocumab in Patients With Hypercholesterolemia Not Adequately Controlled With Non-statin Lipid Modifying Therapy or the Lowest Strength of Statin [Phase 3]
Phase 3 trial results show the efficacy and safety of alirocumab in patients with hypercholesterolemia not adequately controlled with non-st…
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CLINICAL_TRIALS trial_result · 2018-05-07Clinical Trial Update: Efficacy and Safety of a Generic Rosuvastatin in a Real-world Setting
This document reports the completion of a real-world study evaluating the efficacy and safety of a generic rosuvastatin for primary hypercho…
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CLINICAL_TRIALS trial_result · 2018-04-10Clinical Trial Update: Food Matrix and Genetic Variability as Determinants of Bioavailability and Biological Effects of Beta-cryptoxanthin and Phytosterols [Phase 1]
Phase 1 clinical trial update evaluating how food matrix and genetic variability influence the bioavailability and biological effects of bet…
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CLINICAL_TRIALS trial_result · 2018-03-23Clinical Trial Update: NUtraceutical TReatment for hYpercholesterolemia in HIV-infected Patients [Phase 4]
Phase 4 nutraceutical treatment trial for hypercholesterolemia in HIV-infected patients is reported as completed.
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CLINICAL_TRIALS trial_result · 2018-03-09Clinical Trial Update: A Study of the Efficacy and Safety of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-832) [Phase 3]
Phase 3 trial evaluating the efficacy and safety of MK-0653H in Japanese adults with hypercholesterolemia has completed, with results posted…
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CLINICAL_TRIALS trial_result · 2018-02-26Clinical Trial Update: Rosuvastatin and Renal Endothelial Function [Phase 2]
Phase 2 trial update examining the effect of rosuvastatin on renal endothelial function in individuals with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2018-02-12Clinical Trial Update: Evolocumab Versus LDL Apheresis in Patients With Hypercholesterolemia [Phase 3]
Phase 3 trial comparing evolocumab to LDL apheresis in patients with hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2018-01-11Clinical Trial Update: A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384) [Phase 3]
Phase 3 clinical trial evaluating long-term safety and tolerability of MK-0653C in Japanese participants with hypercholesterolemia; complete…
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CLINICAL_TRIALS trial_result · 2018-01-04Clinical Trial Update: GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound [Phase 3]
Phase 3 trial assessing plaque regression with a PCSK9 antibody in hypercholesterolemia, measured by intravascular ultrasound; results have …
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: Monthly And Twice Monthly Subcutaneous Dosing Of PF-04950615 (RN316) In Hypercholesterolemic Subjects On A Statin [Phase 2]
Phase 2 clinical trial evaluating monthly and twice-monthly subcutaneous dosing of PF-04950615 (RN316) in hypercholesterolemia patients on s…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous (SC) Administered Alirocumab in Healthy Chinese Subjects [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of subcutaneous alirocumab in healthy Chinese subjects…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: Nutraceutical in Cardiovascular Primary Prevention [Phase 2]
This clinical trial update indicates a Phase 2 study of a nutraceutical for primary cardiovascular prevention has completed, in participants…
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CLINICAL_TRIALS trial_result · 2017-11-08Clinical Trial Update: A Multiple Dose Study Of PF-04950615 (RN316) In Subjects On Maximum Doses Of Statins [Phase 2]
Pfizer completed a Phase 2 multiple-dose study of PF-04950615 (RN316) in patients on maximum statin therapy to evaluate lipid effects, with …
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: Study Assessing Safety, Immunogenicity and LDLc -Lowering Activity of 2 PCSK9 Targeting AFFITOPE Vaccines in Healthy Subjects [Phase 1]
This Phase 1 trial update reports safety, immunogenicity, and LDL-C lowering activity of two AFFITOPE vaccines targeting PCSK9 in healthy su…
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CLINICAL_TRIALS trial_result · 2017-10-12Clinical Trial Update: Long Term Effects of Plant Sterol and Stanol Esters [NA]
This clinical trial update reports the long-term effects of plant sterol and stanol esters on hypercholesterolemia, based on a completed stu…
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CLINICAL_TRIALS trial_result · 2017-10-11Clinical Trial Update: A Multiple Dose Study of PF-04950615 (RN316) in Subjects on High Doses of Statins [Phase 2]
Phase 2 multiple-dose study of PF-04950615 (RN316) in patients on high-dose statins has completed, with results posted on 2017-10-11.
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CLINICAL_TRIALS trial_result · 2017-10-02Clinical Trial Update: A 6-Month Consumer Behavior Study of a Self-Management System (0803-084)(COMPLETED) [Phase 3]
A Phase 3 trial update for a self-management system studying consumer behavior in hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2017-09-19Clinical Trial Update: The Efficacy and Safety of Combination Therapy of Rosuvastatin and Ezetimibe and Rosuvastatin Monotherapy in Patients With Primary Hypercholesterolemia [Phase 3]
Phase 3 clinical trial updating the efficacy and safety of rosuvastatin plus ezetimibe versus rosuvastatin monotherapy in primary hyperchole…
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CLINICAL_TRIALS trial_result · 2017-09-19Clinical Trial Update: Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment [Phase 3]
Phase 3 trial comparing evolocumab to LDL-C apheresis in patients already receiving apheresis; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-08-28Clinical Trial Update: The Cholesterol-lowering Efficacy of Probiotic Lactobacillus Plantarum in Hypercholesterolaemic Adults [NA]
A completed clinical trial evaluating whether Lactobacillus plantarum probiotic can lower cholesterol in adults.
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CLINICAL_TRIALS trial_result · 2017-08-14Clinical Trial Update: Graves' Orbitopathy and Hypercholesterolemia
A completed clinical trial sponsored by the University of Pisa investigated Graves' orbitopathy and hypercholesterolemia.