Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Enlicitide (MK-0616, Oral PCSK9 Inhibitor) Compared With Ezetimibe or Bempedoic Acid or Ezetimibe and Bempedoic Acid in Adults With Hypercholesterolemia (MK-0616-018/CORALreef AddOn) [Phase 3]

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Summary

A Phase 3 study evaluating the efficacy and safety of Enlicitide (MK-0616) versus ezetimibe, bempedoic acid, or their combination in adults with hypercholestero…

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Diseases / indications

• Hypercholesterolemia

Drugs mentioned

• Enlicitide
• Ezetimibe + Bempedoic acid combination
• Nexletol (bempedoic acid)
• Zetia (ezetimibe)

Snippet

Sponsor: Merck Sharp & Dohme LLC | Conditions: Hypercholesterolemia | Phase 3 | Status: COMPLETED | Results posted: 2026-03-27