Huntington Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: MIG-HD: Multicentric Intracerebral Grafting in Huntington's Disease [Phase 2]
This clinical trial update reports the completion of a Phase 2 multicentric intracerebral grafting study for Huntington's disease.
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CLINICAL_TRIALS trial_result · 2017-09-25Clinical Trial Update: Study in PRE-manifest Huntington's Disease of Coenzyme Q10 (UbiquinonE) Leading to Preventive Trials (PREQUEL) [Phase 2]
Phase 2 trial update for Coenzyme Q10 (ubiquinone) in PRE-manifest Huntington's Disease as a precursor to preventive trials; completed with …
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FDA approval · 2017-09-13FDA Approved: XENAZINE — Supplemental Application (Lundbeck Pharmaceuticals LLC)
FDA approved a supplemental application for Xenazine (tetrabenazine) submitted by Lundbeck Pharmaceuticals LLC.
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CLINICAL_TRIALS trial_result · 2017-08-11Clinical Trial Update: First Time Use of SD-809 in Huntington Disease [Phase 3]
Phase 3 trial update on the first use of SD-809 (deutetrabenazine) for Huntington disease–related chorea.
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CLINICAL_TRIALS trial_result · 2017-08-08Clinical Trial Update: FuRST 2.0 Cognitive Pre-Testing
The FuRST 2.0 cognitive pre-testing trial for Huntington's disease has completed.
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Making Sense of a Positive Genetic Test Result for Huntington Disease
An NHGRI-sponsored clinical trial update discussing how to interpret a positive genetic test result for Huntington disease; the trial status…
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CLINICAL_TRIALS research · 2017-06-20Clinical Trial Update: Healthy Volunteer Positron Emission Tomography (PET) Brain Occupancy Study of a Phosphodiesterase 4 (PDE4) Inhibitor in Huntington's Disease [Phase 1]
A Phase 1 PET brain occupancy study in healthy volunteers assessed a PDE4 inhibitor. Huntington's disease was listed as the condition, and t…
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CLINICAL_TRIALS research · 2017-06-15Clinical Trial Update: A Repeat Dose Study in Healthy Volunteers Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK356278 [Phase 1]
A Phase 1 repeat-dose study in healthy volunteers evaluated safety, tolerability, pharmacokinetics and pharmacodynamics of GSK356278; the tr…
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CLINICAL_TRIALS withdrawal · 2017-05-05Clinical Trial Update: Characterization of the Profile of Dysarthria in Huntington's Disease, Using the Clinical Evaluation Battery of Dysarthria [NA]
A clinical trial update noting the withdrawal of NCT03142217, a study characterizing dysarthria in Huntington's disease conducted by Centre …
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CLINICAL_TRIALS research · 2017-04-18Clinical Trial Update: Beta Testing of a New Assessment in Huntington's Disease (HD) [NA]
This document provides an update on a clinical trial beta testing a new assessment for Huntington's disease, with no phase or current status…
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FDA approval · 2017-04-03FDA Approved: AUSTEDO — Original Application (Teva Neuroscience, Inc.)
FDA approved AUSTEDO (deutetrabenazine) in an original application for the treatment of chorea in Huntington's disease.
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FDA approval · 2017-01-31FDA Approved: TETRABENAZINE — Original Application (Precision Dose Inc.)
FDA approved the original ANDA for tetrabenazine by Precision Dose Inc., enabling a generic version of the Huntington's disease chorea treat…
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: Evaluation of [123I]MNI-420 and SPECT as a Marker of the Adenosine A2a Receptor in PD, HD and Healthy Subjects. [Phase 1]
Phase 1 study evaluating [123I]MNI-420 with SPECT as a marker of the adenosine A2a receptor in Parkinson disease, Huntington disease, and he…
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions [Phase 1]
Phase 1 PET imaging study of an mGluR5 tracer across several neuropsychiatric conditions has been completed.
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Study of Motor Slowing in Parkinson's Disease by a Computerized Mental Chronometry Paradigm
This completed clinical trial investigated motor slowing in Parkinson's disease using a computerized mental chronometry paradigm. Huntington…
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CLINICAL_TRIALS research · 2016-11-01Clinical Trial Update: A Pre-Cellular Therapy Observational Study in Early Huntington's Disease
Completed observational study in Huntington's disease conducted by the University of California, Davis, examining early-stage disease prior …
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CLINICAL_TRIALS other · 2016-10-14Clinical Trial Update: PINS Stimulator System for Deep Brain Stimulation in Huntington's Disease [NA]
Clinical trial update for the PINS Stimulator System in Huntington's disease; current status is unknown.
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: A Safety and Efficacy Study of Dimebon in Patients With Huntington Disease [Phase 3]
A Phase 3 clinical trial evaluating the safety and efficacy of dimebon (latrepirdine) in Huntington disease has completed.
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington Disease [Phase 3]
This update reports the termination of an extension of the HORIZON trial evaluating the safety of Dimebon (latrepirdine) in Huntington's dis…
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CLINICAL_TRIALS trial_result · 2016-10-10Clinical Trial Update: Working Memory Training in Huntington's Disease [NA]
This clinical trial update indicates that the study evaluating working memory training for Huntington's disease has completed.
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: Treadmill Walking in Individuals With Dementia With Lewy Bodies and Huntington's Disease [NA]
This clinical trial update indicates that the treadmill walking study involving individuals with Huntington's disease and dementia with Lewy…
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CLINICAL_TRIALS trial_result · 2016-09-20Clinical Trial Update: Study to Assess the Safety, Tolerability and Pharmacokinetic Profile of PBF-999 "After Multiple Oral Doses" in Healthy Volunteers [Phase 1]
Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of PBF-999 after multiple oral doses in healthy volunteers; the tria…
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CLINICAL_TRIALS trial_result · 2016-08-23Clinical Trial Update: Caregiver Burden in Huntington's Disease [NA]
This clinical trial update notes the completed status of a study evaluating caregiver burden in Huntington's disease patients, conducted by …
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Effect of PBT2 in Patients With Early to Mid Stage Huntington Disease [Phase 2]
Phase 2 trial of PBT2 in patients with early to mid-stage Huntington disease has been completed, with results posted.
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CLINICAL_TRIALS trial_result · 2016-06-01Clinical Trial Update: [PETDE10] Imaging of PDE10A Enzyme Levels in Huntington's Disease Gene Expansion Carriers and Healthy Controls With PET. [EARLY_Phase 1]
This record reports the completion of a Phase 1 PET imaging trial evaluating PDE10A enzyme levels in Huntington's disease gene expansion car…