Huntington Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-05-27Clinical Trial Update: Bioavailability of Ubiquinol in Huntington Disease [Phase 1]
Phase 1 study evaluated the bioavailability of ubiquinol in individuals with Huntington's disease and is completed.
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CLINICAL_TRIALS trial_result · 2016-03-30Clinical Trial Update: Coenzyme Q10 in Huntington's Disease (HD) [Phase 3]
A Phase 3 trial of Coenzyme Q10 for Huntington's disease was terminated, and the results have been posted.
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CLINICAL_TRIALS trial_result · 2016-03-24Clinical Trial Update: Proof of Concept of an Anaplerotic Study Using Brain Phosphorus Magnetic Resonance Spectroscopy in Huntington Disease [Phase 2]
Phase 2 proof-of-concept study in Huntington's disease evaluating an anaplerotic approach using brain phosphorus MR spectroscopy; results we…
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CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E) [Phase 3]
The Phase 3 CREST-E trial evaluating creatine for Huntington's disease has been terminated.
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CLINICAL_TRIALS trial_result · 2016-03-08Clinical Trial Update: Study To Assess the Safety and Tolerability of Single Ascending Oral Doses of PBF-999 in Healthy Young Male Volunteers [Phase 1]
Phase 1 study assessing safety and tolerability of single ascending oral doses of PBF-999 in healthy young male volunteers; Huntington's dis…
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FDA approval · 2016-02-03FDA Approved: TETRABENAZINE — Original Application (Camber Pharmaceuticals, Inc.)
FDA approved Camber Pharmaceuticals' generic tetrabenazine under an original ANDA.
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CLINICAL_TRIALS trial_result · 2015-11-25Clinical Trial Update: A Phase II Safety and Tolerability Study With SEN0014196 [Phase 2]
Phase II safety and tolerability study of SEN0014196 for Huntington's disease has completed.
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CLINICAL_TRIALS trial_result · 2015-11-25Clinical Trial Update: An Exploratory Clinical Trial in Early Stage Huntington's Disease Patients With SEN0014196 [Phase 1]
A Phase 1 exploratory trial of SEN0014196 in early-stage Huntington's disease patients has completed, according to ClinicalTrials.gov.
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CLINICAL_TRIALS trial_result · 2015-09-30Clinical Trial Update: Feasibility of a Video-oculography in Patients With Huntington's Disease VOG-HD Study [NA]
This document provides a clinical trial update on the feasibility of using video-oculography to assess Huntington's disease in the VOG-HD st…
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CLINICAL_TRIALS research · 2015-09-16Clinical Trial Update: Functional Imaging of Social Cognition in Premanifest Huntington's Disease [NA]
A clinical trial update for a study on functional imaging of social cognition in individuals with premanifest Huntington's disease; current …
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CLINICAL_TRIALS research · 2015-09-07Clinical Trial Update: Assessment of Social-emotional Functioning in Neurological Diseases [NA]
This clinical trial update notes the completion of a study evaluating social-emotional functioning in multiple neurological diseases. Diseas…
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FDA approval · 2015-08-25FDA Approved: XENAZINE — Supplemental Application (Lundbeck Pharmaceuticals LLC)
The FDA approved a supplemental application for Xenazine (tetrabenazine) from Lundbeck Pharmaceuticals LLC.
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FDA approval · 2015-08-17FDA Approved: TETRABENAZINE — Original Application (Sun Pharmaceutical Industries, Inc.)
FDA approved Sun Pharmaceutical Industries' original application for tetrabenazine (generic), expanding access to a VMAT2 inhibitor for Hunt…
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CLINICAL_TRIALS trial_result · 2015-06-16Clinical Trial Update: Effects of EGCG (Epigallocatechin Gallate) in Huntington's Disease (ETON-Study) [Phase 2]
A Phase 2 trial evaluating epigallocatechin gallate (EGCG) for Huntington disease has completed (ETON-Study), sponsored by Charité Universit…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: A Study of the Novel Drug Dimebon in Patients With Huntington's Disease [Phase 2]
The document reports the completion of a Phase 2 clinical study evaluating Dimebon for Huntington's disease. No efficacy or safety results a…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Minocycline in Patients With Huntington's Disease [Phase 1, Phase 2]
The document reports completion of a Phase 1/Phase 2 trial evaluating minocycline in patients with Huntington's disease.
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CLINICAL_TRIALS research · 2014-10-09Clinical Trial Update: Study of Biomarkers That Predict the Evolution of Huntington's Disease
This entry describes an ongoing study evaluating biomarkers that may predict how Huntington's disease progresses.
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CLINICAL_TRIALS research · 2014-09-17Clinical Trial Update: Safety and Efficacy of Bone Marrow Derived MNCs for Treatment of Cells for the Treatment of Hunting Tons Chorea. [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating the safety and potential efficacy of bone marrow-derived mononuclear cells…
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CLINICAL_TRIALS trial_result · 2014-09-09Clinical Trial Update: Apathy Cure Through Bupropion in Huntington's Disease [Phase 2]
Phase 2 trial assessing whether bupropion can improve apathy in Huntington's disease has completed.
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CLINICAL_TRIALS research · 2014-04-02Clinical Trial Update: Multicentric Trial of the Treatment of Huntington's Disease by Cysteamine (RP103) [Phase 2, Phase 3]
Clinical update on a multicenter Phase 2/Phase 3 trial evaluating cysteamine (RP103) for Huntington's disease. The current status of the stu…
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CLINICAL_TRIALS trial_result · 2014-02-10Clinical Trial Update: Premanifest Huntington's Disease Extension Study II: Creatine Safety & Tolerability [Phase 2]
This Phase 2 extension study in premanifest Huntington's disease evaluated the safety and tolerability of creatine and has completed.
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CLINICAL_TRIALS trial_result · 2014-02-10Clinical Trial Update: Creatine Safety and Tolerability in Premanifest HD: PRECREST [Phase 2]
This Phase 2 study (PRECREST) evaluated the safety and tolerability of creatine in individuals with premanifest Huntington disease and has c…
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CLINICAL_TRIALS trial_result · 2014-02-10Clinical Trial Update: Premanifest Huntington's Disease: Creatine Safety & Tolerability Extension Study [Phase 2]
Phase 2 extension study assessing safety and tolerability of creatine in premanifest Huntington's disease has completed.
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FDA approval · 2013-08-02FDA Approved: XENAZINE — Supplemental Application (Lundbeck Pharmaceuticals LLC)
FDA approved a supplemental application for Xenazine (tetrabenazine) submitted by Lundbeck Pharmaceuticals LLC.
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CLINICAL_TRIALS trial_result · 2013-04-19Clinical Trial Update: Pilot Study of Minocycline in Huntington's Disease [Phase 2, Phase 3]
This document reports the posting of results from a Phase 2/Phase 3 pilot study of minocycline in Huntington's disease.