Huntington Disease
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Sign up freeTop drugs studied for this disease
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FDA approval · 2020-03-17FDA Approved: TETRABENAZINE — Original Application (Apotex Corp.)
FDA approved Apotex's generic tetrabenazine through an original application, expanding access to treatment for Huntington disease–related ch…
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FDA approval · 2020-01-22FDA Approved: TETRABENAZINE — Original Application (Slate Run Pharmaceuticals, LLC)
FDA approved the original application for tetrabenazine from Slate Run Pharmaceuticals, LLC, enabling the marketing of a generic tetrabenazi…
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: A Trial of Memantine as Symptomatic Treatment for Early Huntington Disease [Phase 2]
A Phase 2 clinical trial evaluating memantine as symptomatic treatment for early Huntington disease has been completed.
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CLINICAL_TRIALS trial_result · 2019-09-16Clinical Trial Update: Efficacy and Safety of SOM3355 in Huntington's Disease Chorea [Phase 2]
Phase 2 trial update reporting efficacy and safety of SOM3355 in Huntington's disease chorea.
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FDA label_change · 2019-07-15FDA Approved: AUSTEDO — Supplemental Application (Teva Neuroscience, Inc.)
The FDA approved Teva's supplemental application for Austedo (deutetrabenazine) to update the product labeling. This likely reflects changes…
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FDA approval · 2019-07-01FDA Approved: HALOPERIDOL — Original Application (Fresenius Kabi USA, LLC)
FDA approved the original application for haloperidol lactate (HALOPERIDOL LACTATE) as a generic injectable from Fresenius Kabi USA, LLC.
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CLINICAL_TRIALS trial_result · 2019-06-19Clinical Trial Update: A Clinical Study in Participants With Huntington's Disease (HD) to Assess Efficacy and Safety of Three Oral Doses of Laquinimod [Phase 2]
Phase 2 trial evaluating three oral doses of laquinimod in Huntington's disease has been completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-05-31Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 443139 in Participants With Early Manifest Huntington's Disease [Phase 1, Phase 2]
A Phase 1/2 study assessing safety, tolerability, pharmacokinetics, and pharmacodynamics of ISIS 443139 in individuals with early manifest H…
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CLINICAL_TRIALS trial_result · 2019-05-30Clinical Trial Update: Feasibility and Acceptability of Implementing a Clinic-based Physical Activity Coaching Intervention in People With Premanifest and Early Stage HD [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating the feasibility and acceptability of a clinic-based physical activity coaching intervention …
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Alternatives for Reducing Chorea in Huntington Disease [Phase 3]
Phase 3 trial evaluating alternatives for reducing chorea in Huntington disease has completed with results posted.
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CLINICAL_TRIALS research · 2019-02-07Clinical Trial Update: Genetic Risk: Whether, When, and How to Tell Adolescents
A completed Johns Hopkins clinical trial examining when and how to communicate genetic risk information to adolescents for Huntington's dise…
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CLINICAL_TRIALS research · 2019-01-24Clinical Trial Update: Wearable Sensors for Quantitative Assessment of Motor Impairment in Huntington's Disease Huntington's Disease
This document provides an update on a clinical trial evaluating wearable sensors for quantitative assessment of motor impairment in Huntingt…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Accelerated Diffusion MRI for Diagnosis of Hungtington Disease
The trial update reports completion of a study evaluating accelerated diffusion MRI as a diagnostic method for Huntington disease.
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CLINICAL_TRIALS trial_result · 2018-06-13Clinical Trial Update: Exercise Effects in Huntington's Disease [NA]
This update reports a completed trial evaluating the effects of exercise on Huntington's disease.
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FDA label_change · 2018-06-06FDA Approved: AUSTEDO — Supplemental Application (Teva Neuroscience, Inc.)
FDA approved a supplemental application for AUSTEDO (deutetrabenazine) filed by Teva Neuroscience, updating the drug's labeling.
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Open Label Extension Study To Investigate Long Term Safety, Tolerability And Efficacy Of Pf-02545920 In Subjects With Huntington's Disease Who Completed Study A8241021 [Phase 2]
Pfizer conducted an open-label extension to evaluate the long-term safety, tolerability, and efficacy of Pf-02545920 in Huntington's disease…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Evaluating the Relationship of Morphine Consumption and Pain-related Molecules in Hepatic Surgical Patients
Completed clinical trial evaluating the relationship between morphine consumption and pain-related biomarkers in hepatic surgical patients.
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CLINICAL_TRIALS trial_result · 2018-01-29Clinical Trial Update: Study Exploring Safety, Pharmacokinetic and Pharmacodynamic of BN82451 in Male Huntington's Disease Patients [Phase 2]
A Phase 2 trial evaluating the safety, pharmacokinetics, and pharmacodynamics of BN82451 in males with Huntington's disease was terminated; …
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CLINICAL_TRIALS trial_result · 2018-01-19Clinical Trial Update: Neuroleptic and Huntington Disease Comparison of : Olanzapine, la Tetrabenazine and Tiapride [Phase 3]
A Phase 3 clinical trial comparing olanzapine, tetrabenazine, and tiapride for Huntington disease has completed.
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FDA approval · 2018-01-08FDA Approved: TETRABENAZINE — Original Application (Dr. Reddys Laboratories Inc)
FDA approved Dr. Reddy's Laboratories' generic tetrabenazine (ANDA 209284) as an original application for Huntington's disease–related chore…
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FDA approval · 2017-12-18FDA Approved: TETRABENAZINE — Original Application (Bionpharma Inc.)
FDA approved Bionpharma Inc.'s original Abbreviated New Drug Application for tetrabenazine, a generic treatment for chorea associated with H…
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CLINICAL_TRIALS trial_result · 2017-12-14Clinical Trial Update: Study Evaluating The Safety, Tolerability And Brain Function Of 2 Doses Of PF-0254920 In Subjects With Early Huntington's Disease [Phase 2]
Phase 2 trial evaluating safety, tolerability, and brain function of two doses of PF-0254920 in early Huntington's disease completed with re…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Randomized, Placebo Controlled Study Of The Efficacy And Safety Of PF-02545920 In Subjects With Huntington's Disease [Phase 2]
A randomized, placebo-controlled Phase 2 trial evaluating the efficacy and safety of PF-02545920 in Huntington's disease was completed, with…
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CLINICAL_TRIALS research · 2017-11-01Clinical Trial Update: Metabolomic Study in Huntington's Disease (METABO-HD) [NA]
A clinical trial update on the METABO-HD metabolomics study for Huntington's disease, sponsored by University Hospital, Angers; the status i…
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CLINICAL_TRIALS trial_result · 2017-10-19Clinical Trial Update: Impact of Xenazine(Tetrabenazine)on Gait and Functional Activity in Individuals With Huntington's Disease
A completed clinical trial evaluated the impact of Xenazine (tetrabenazine) on gait and functional activity in individuals with Huntington's…