High-grade Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy [Phase 2]
This Phase 2, NCI-sponsored trial evaluated cilengitide in children and adolescents with recurrent or progressive high-grade glioma refracto…
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CLINICAL_TRIALS trial_result · 2013-10-29Clinical Trial Update: Temozolomide in Treating Patients With Recurrent High-Grade Glioma [Phase 2]
Phase 2 clinical trial of temozolomide in patients with recurrent high-grade glioma has completed with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-10-08Clinical Trial Update: Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma [Phase 2]
Phase 2 clinical trial update evaluating tipifarnib in pediatric patients with recurrent or progressive brain tumors has completed, reportin…
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CLINICAL_TRIALS trial_result · 2013-09-30Clinical Trial Update: Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors [Phase 1]
This Phase 1 trial evaluates the combination of temozolomide and O6-benzylguanine in pediatric patients with recurrent brain tumors.
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CLINICAL_TRIALS trial_result · 2013-06-24Clinical Trial Update: Pharmacologic Study of Methotrexate in Patients Undergoing Stereotactic Biopsy for Recurrent High-Grade Glioma [NA]
A completed clinical trial update describing a pharmacologic study of methotrexate in patients with recurrent high-grade glioma undergoing s…
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CLINICAL_TRIALS trial_result · 2013-05-14Clinical Trial Update: Borderzone Sampling [NA]
Clinical trial update noting completion of a Maastricht University Medical Center study on borderzone sampling in high-grade glioma and glio…
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: Protocol to Distinguish Tumor Recurrence From Treatment-Related Necrosis in Patients With High Grade Gliomas
This completed clinical trial investigates a protocol to distinguish tumor recurrence from treatment-related necrosis in patients with recur…
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CLINICAL_TRIALS trial_result · 2013-02-18Clinical Trial Update: Carmustine Wafers Plus Irinotecan in Treating Patients With Recurrent Supratentorial High Grade Gliomas [Phase 1]
A Phase 1 clinical trial evaluating the combination of Carmustine wafers and Irinotecan for patients with recurrent supratentorial high-grad…
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CLINICAL_TRIALS trial_result · 2013-01-10Clinical Trial Update: Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade Glioma [Phase 1]
Phase 1 study of capecitabine with radiation therapy in young patients with newly diagnosed nonmetastatic brain stem glioma or high-grade gl…
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CLINICAL_TRIALS trial_result · 2012-07-06Clinical Trial Update: Bevacizumab and Irinotecan to Treat Brain Tumors [Phase 2]
A Phase 2 trial evaluating bevacizumab in combination with irinotecan for high-grade gliomas was terminated, and results were posted in July…
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CLINICAL_TRIALS trial_result · 2012-06-08Clinical Trial Update: Bevacizumab for Recurrent Malignant Glioma [Phase 2]
A Phase 2 trial evaluating bevacizumab for recurrent malignant glioma reported results (posted in 2012).
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CLINICAL_TRIALS trial_result · 2012-05-04Clinical Trial Update: Assessment of 18FLT PET-CT for Volume Definition of High-grade Gliomas (GLIO-TEP) [Phase 1, Phase 2]
This clinical trial update assesses 18F-FLT PET-CT for defining tumor volumes in high-grade gliomas, including astrocytoma and glioblastoma,…
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CLINICAL_TRIALS trial_result · 2012-03-08Clinical Trial Update: Talampanel in Treating Patients With Recurrent High-Grade Glioma [Phase 2]
Phase 2 clinical trial of talampanel for recurrent high-grade glioma has completed.
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CLINICAL_TRIALS trial_result · 2010-08-12Clinical Trial Update: Trans Sodium Crocetinate (TSC) Study of Intra-tumoral Oxygen Concentration, Safety, and Pharmacokinetics in Patients With High Grade Glioma [Phase 1]
A Phase 1 study of Trans Sodium Crocetinate (TSC) in patients with high-grade glioma has been terminated. The update covers intra-tumoral ox…
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CLINICAL_TRIALS trial_result · 2010-08-11Clinical Trial Update: Radiation Therapy, Arsenic Trioxide, and Temozolomide in Treating Patients With Newly Diagnosed High-Grade Glioma [Phase 1]
Phase 1 study evaluating the combination of radiation therapy, arsenic trioxide, and temozolomide in newly diagnosed high-grade glioma has c…
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CLINICAL_TRIALS trial_result · 2010-01-20Clinical Trial Update: A Phase II Study Of Gliadel, Concomitant Temozolomide And Radiation, Followed By Dose Dense Therapy With Temozolomide Plus Bevacizumab For Newly Diagnosed Malignant High Grade Glioma [Phase 2]
A Phase II study evaluates Gliadel wafers with temozolomide and radiation, followed by dose-dense temozolomide plus bevacizumab, for newly d…
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CLINICAL_TRIALS trial_result · 2010-01-20Clinical Trial Update: A Phase II Study of Gliadel, Concomitant Temozolomide and Radiation, Followed By Dose Dense Therapy With Temozolomide For Newly Diagnosed Malignant High Grade Glioma [Phase 2]
A Phase II clinical trial is evaluating Gliadel implants with concurrent temozolomide and radiation, followed by dose-dense temozolomide, fo…
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CLINICAL_TRIALS trial_result · 2009-10-21Clinical Trial Update: TP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade Glioma [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating TP-38 toxin in pediatric patients with recurrent or progressive supratentorial high-grade glioma…
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CLINICAL_TRIALS trial_result · 2009-09-18Clinical Trial Update: Gliadel Wafer, Temozolomide and Radiation Therapy for Newly Diagnosed GBM [Phase 2]
Phase 2 trial evaluating Gliadel Wafer with Temozolomide and radiation for newly diagnosed glioblastoma multiforme/high-grade glioma has bee…
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CLINICAL_TRIALS trial_result · 2009-02-02Clinical Trial Update: Exploratory, Phase 0 Study of Positron Emission Tomography (PET) Imaging Agent, F-18 RGD-K5 [EARLY_Phase 1]
Siemens Molecular Imaging completed an exploratory Phase 0 PET imaging study of the F-18 RGD-K5 tracer. The study evaluated imaging across m…
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CLINICAL_TRIALS trial_result · 2007-11-21Clinical Trial Update: Nimotuzumab in Children With HGG
A completed clinical trial investigating Nimotuzumab in children with high-grade glioma; the update notes trial status without detailing res…