Records containing: High-grade Glioma
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CLINICAL_TRIALS study record update · 2026-03-24A Phase I, Open-Label, Single/Multiple Dose, Dose-escalation Study to Evaluate the Safety, Tolerability and Antitumor Activity of TX103 CAR-T Cell Injection (TX103) in Subjects With Recurrent or Progressive Grade 4 Glioma.
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CLINICAL_TRIALS study record update · 2026-03-18A Phase 1, First-in-Human, Biomarker-Guided, Dose-Escalation and Expansion Study of Locoregional Dual-Targeting CAR-NK Cells Directed Against IL13Rα2, EGFR/EGFRvIII, and/or B7-H3 (CD276) in Adults With Recurrent or Progressive Glioblastoma or High-Grade Glioma
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CLINICAL_TRIALS study record update · 2026-03-16A Single-arm Clinical Study on the Efficacy and Safety of the Novel Oncolytic Virus Ad-TD-nsIL12 Combined With PD-1 Inhibitor in the Treatment of Recurrent High-grade Glioma
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CLINICAL_TRIALS study record update · 2026-03-13Phase I Study -To Assess Safety and Feasibility of IL-8 Receptor Modified Patient-derived Activated CD70 CAR T Cell Therapy in CD70+ Adult GBM and Pediatric High-Grade Gliomas (pHGG)
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CLINICAL_TRIALS study record update · 2026-03-09INSIGHT MRL: INtegrating Biology for Safe Intensification of Glioblastoma Hypofractionated Treatment on the MR-Linac
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CLINICAL_TRIALS study record update · 2026-02-10Phase II Clinical Trial of HSV G207 With a Single 5 Gy Radiation Dose in Children With Recurrent High-Grade Glioma
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CLINICAL_TRIALS study record update · 2026-02-05A Phase 1/2 Study of Pegylated Arginine Deiminase (ADI-PEG 20) Plus Radiotherapy (RT) and Temozolomide (TMZ) in Children, Adolescents, and Young Adults With Newly Diagnosed High-grade Glioma (HGG)
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CLINICAL_TRIALS study record update · 2026-01-02A Phase IB Study to Assess Safety of Concurrent Azeliragon With Craniospinal Irradiation in Patients With Leptomeningeal Metastasis From Solid Tumor Malignancies or High-Grade Gliomas
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CLINICAL_TRIALS study record update · 2025-12-03An Investigator-Initiated Study to Evaluate PSMA Expression in Patients With High-Grade Gliomas or Brain Metastases With 68Ga-PSMA-11 PET
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CLINICAL_TRIALS study record update · 2025-11-20Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors
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CLINICAL_TRIALS study record update · 2025-08-08Multi-Dimensional MRI Spatial Heterogeneity Analysis for Predicting Key Genes and Prognosis of High-Grade Gliomas: A Multi-Center Study
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CLINICAL_TRIALS study record update · 2025-07-22Atovaquone Combined With Radiation in Children With Malignant Brain Tumors
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CLINICAL_TRIALS study record update · 2025-02-18Phase II Clinical Study of Carbon Ion Combined with Photon Radiotherapy for High-grade Glioma
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CLINICAL_TRIALS study record update · 2025-01-15SeizURe Frequency During a Radiotherapy COurse for High-Grade Gliomas
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CLINICAL_TRIALS study record update · 2024-12-17A Single-arm, Dose-escalation Phase I Clinical Study on Evaluating the Tolerability, Pharmacokinetic Characteristics, Safety and Preliminary Efficacy of MT027 in Patients with Recurrent or Progressive High-grade Glioma
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CLINICAL_TRIALS study record update · 2024-12-16Surgical Suction Aspirates Fluorescence Measurement
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CLINICAL_TRIALS study record update · 2024-11-29A Phase 1b Open-Label Study Investigating the Tolerability, Safety, and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma
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CLINICAL_TRIALS study record update · 2024-02-22The SUPRAMAX-study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)
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CLINICAL_TRIALS study record update · 2024-01-11Study of Adaptive Radiotherapy for High-grade Glioma Based on Interfraction Magnetic Resonance Imaging (MRI)
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CLINICAL_TRIALS study record update · 2023-11-28Nurse-led Family and Network Consultations - Addressing Cancer-Related Symptoms and Concerns in Patients With High-grade Glioma and Their Families and Network (CARES)
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CLINICAL_TRIALS study record update · 2023-09-26Evaluating the Impact of 2D Non-Navigated Intraoperative Ultrasound on Extent of Resection and Patients' Outcome in Glioma Surgery: A Retrospective Study
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CLINICAL_TRIALS study record update · 2023-07-03Multispectral and Bimodal Fluorescent Guided Surgery (FGS) of High-grade Glioma for Refining Margin Assessment: A Phase 1 Dose Finding Study Using Cetuximab-IRDye800CW Combined With 5-ALA.
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CLINICAL_TRIALS study record update · 2023-03-24Phase 1/2 Study of Bempegaldesleukin in Combination With Nivolumab in Children, Adolescents, and Young Adults With Recurrent or Refractory Malignancies (PIVOT IO 020)
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CLINICAL_TRIALS study record update · 2023-01-11To Determine Whether the Habitats Created by the Preoperative or Postoperative Multiparametric MRI Can Predict IDH Mutation Status, Prognosis, Recurrence or Intracranial Distant Recurrence of the Patients With High-grade Gliomas
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CLINICAL_TRIALS study record update · 2022-12-20A Phase 1/2, Open-label, Dose-exploration and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NTX-301 Monotherapy in Advanced Solid Tumours, and in Combination With Platinum-based Chemotherapy in Advanced Ovarian & Bladder Cancer, and in Combination With Temozolomide as Adjuvant (Maintenance) Therapy in High-grade Glioma (Optional Arm)