Clinical Trial Update: Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors [Phase 1]

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Summary

This Phase 1 trial evaluates the combination of temozolomide and O6-benzylguanine in pediatric patients with recurrent brain tumors.

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Diseases / indications

• Choroid Plexus Tumor
• Cns Germ Cell Tumor
• Craniopharyngioma
• Ependymoma
• High-grade Glioma
• Medulloblastoma
• Meningioma
• Primitive Neuroectodermal Tumor

Drugs mentioned

• O6-Benzylguanine (O6-Benzylguanine)
• Temodar (Temozolomide)

Snippet

Sponsor: National Cancer Institute (NCI) | Conditions: Childhood Central Nervous System Germ Cell Tumor, Childhood Choroid Plexus Tumor | Phase 1 | Status: COMPLETED