Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Exercise Prehabilitation in Patients With Head and Neck Squamous-cell Carcinoma: The FIT4TREAT Trial [NA]
This clinical-trial update reports the FIT4TREAT trial evaluating exercise prehabilitation in patients with head and neck squamous cell carc…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: GV20-0251 and Sintilimab for Neoadjuvant Treatment of Resectable Head and Neck Squamous Cell Carcinoma: A Single-Arm Study [Phase 1]
A Phase 1, single-arm neoadjuvant study evaluating GV20-0251 in combination with Sintilimab for patients with resectable head and neck squam…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC [Phase 1]
A Phase 1 clinical trial update for EPI-326 in EGFR-mutant non-small cell lung cancer and head and neck squamous cell carcinoma; the study i…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Nano-Carbon Iron Suspension Injection Combined With Radiotherapy for Solid Tumors Phase II Clinical Trial [Phase 2]
This is a Phase II clinical trial evaluating Nano-Carbon Iron Suspension Injection in combination with radiotherapy for solid tumors. The st…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: First Line Weekly Chemo/Immunotherapy for Metastatic Head/Neck Squamous Cell Carcinoma Patients [Phase 2]
Phase 2 trial evaluating first-line weekly chemotherapy combined with immunotherapy for metastatic head and neck squamous cell carcinoma; th…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors [Phase 2]
A Phase 2 clinical trial evaluating Volrustomig as monotherapy or in combination with anti-cancer agents across multiple advanced/metastatic…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4 [Phase 1]
Phase 1/1b trial evaluating RNDO-564 as a single agent or in combination with pembrolizumab in bladder cancer and nectin-4–associated solid …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV [Phase 1]
This is a Phase 1 clinical trial evaluating the combination of cabozantinib (XL184) and nivolumab in patients with various advanced cancers …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Comparing Postoperative Adjuvant Cisplatin Concurrent Chemoradiotherapy With Adjuvant Radiotherapy Alone for Intermediate-risk Head and Neck Squamous Cell Carcinoma [Phase 3]
Phase 3 clinical trial evaluating whether postoperative adjuvant cisplatin-based chemoradiotherapy improves outcomes compared with adjuvant …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC [Phase 2, Phase 3]
FORTIFI-HN01 is a Phase 2/3 trial evaluating Ficerafusp Alfa (BCA101) with pembrolizumab versus placebo with pembrolizumab in first-line PD-…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating whether combining Fianlimab with Cemiplimab improves treatment of recurrent or metastatic head and neck sq…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Durvalumab in Combination With Docetaxel, Cisplatin and 5-FU for Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 1]
Phase 1 study evaluating durvalumab in combination with docetaxel, cisplatin, and 5-fluorouracil for locally advanced head and neck squamous…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations [Phase 1, Phase 2]
Phase 1/2 trial of TER-2013 in solid tumors harboring AKT/PI3K/PTEN alterations is currently recruiting to assess safety and preliminary eff…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery [Phase 2]
A Phase 2 clinical trial is assessing the addition of cisplatin to postoperative radiation therapy for stage III-IV squamous cell carcinoma …
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Using MASL to Combat Oral Cancer [EARLY_Phase 1]
This update reports the completion and posted results of an early-phase 1 clinical trial evaluating MASL for head and neck squamous cell car…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Effect of Postbiotics on Microbiota and Systemic Immunomodulation of Pembrolizumab as First-Line Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (RM HNSCC) [Phase 2]
Phase 2 trial evaluating the effect of postbiotics on microbiota and systemic immunomodulation of pembrolizumab as first-line therapy in rec…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC) [Phase 2]
Phase 2 trial exploring neoadjuvant XL-092 (zanzalintinib) with pembrolizumab (Keytruda) for surgically resectable, HPV-negative oral cavity…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Study of CHS-114 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating CHS-114 in participants with advanced solid tumors, including head and neck squamous cell carcinoma; currently recr…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors [Phase 1]
This update reports on a Phase 1 trial testing the combination of sonidegib and pembrolizumab in patients with various advanced solid tumors…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Radiotherapy in Association With Cetuximab in Patients Treated for an Epidermoid Cancer
This clinical trial update reports the completion of a study evaluating radiotherapy in combination with cetuximab for epidermoid head and n…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer [Phase 2]
A Phase 2 clinical trial evaluating cetuximab after immunotherapy for head and neck squamous cell carcinoma (including recurrent and metasta…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Hypofractionated Adjuvant Radiotherapy for Resected Head and Neck Cancers [NA]
The document reports completion and posting of results for a trial evaluating hypofractionated adjuvant radiotherapy in resected head and ne…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors [Phase 1]
A Phase 1 clinical trial evaluating a gene-modified immune cell therapy after a conditioning regimen for metastatic melanoma and other metas…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Alpha Lipoic Acid to Decrease Pain and Side Effects in Concurrent Treatment of HNSCC [Phase 1]
Phase 1 clinical trial evaluating whether alpha-lipoic acid reduces pain and side effects during concurrent treatment of head and neck squam…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy [Phase 3]
A Phase 3 global study evaluating Volrustomig (MEDI5752) in participants with unresected locally advanced head and neck squamous cell carcin…