Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: FID-007 and Cetuximab in Treating Patients With Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating FID-007 in combination with cetuximab for advanced head and neck squamous cell carcinoma is currently ac…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Development of Patient Derived Xenografts (PDXs) and Analysis of Tyrosine Kinase Receptor Expression in Patients With Squamous Cell Head and Neck Cancer (HNSCC) to Study Resistance Mechanisms Induced by Standard Therapy
This clinical trial update describes developing patient-derived xenografts from head and neck squamous cell carcinoma patients and analyzing…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC [Phase 3]
Phase 3 trial of JNJ-90301900 (NBTXR3) activated by radiotherapy with or without cetuximab for locally advanced head and neck squamous cell …
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Radiotherapy With Pembrolizumab in Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) [Phase 2]
Phase 2 trial update evaluating radiotherapy with pembrolizumab for metastatic head and neck squamous cell carcinoma; the study was terminat…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors [Phase 1]
A Phase 1 study evaluating Zanzalintinib in combination with immuno-oncology agents in patients with various solid tumors; recruitment is on…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors [Phase 1, Phase 2]
A Mayo Clinic-sponsored phase 1/2 trial evaluating a personalized neoantigen peptide-based vaccine in combination with pembrolizumab for adv…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Losartan, Pembrolizumab and Stereotactic Body Radiation Therapy for the Treatment of Patients With Locally Recurrent, Refractory or Oligometastatic Head and Neck Squamous Cell Carcinoma [Phase 1]
This Phase 1 clinical trial is evaluating the combination of losartan, pembrolizumab, and stereotactic body radiation therapy for locally re…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Efficacy and Safety Evaluation of VS-101 in Combination With Chemoradiotherapy in Patients With Head and Neck Cancer [Phase 2]
Phase 2 clinical trial evaluating VS-101 in combination with chemoradiotherapy for head and neck squamous cell carcinoma is currently recrui…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: DCSZ11 in Combination With Standard Therapy in Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 trial evaluating DCSZ11 in combination with standard therapy for advanced or metastatic solid tumors is currently recruiting. Th…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Safety and Feasibility of Nivolumab-IRDye800CW in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC) [Phase 1]
Phase 1 clinical trial evaluating the safety and feasibility of Nivolumab-IRDye800CW in patients with head and neck squamous cell carcinoma;…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Study Testing Emactinib Sulfate With Chemotherapy and Immunotherapy Before Surgery for Advanced Head and Neck Cancer [Phase 2]
This entry reports a Phase 2 clinical trial evaluating emactinib sulfate in combination with chemotherapy and immunotherapy before surgery f…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 3]
Phase 3 trial evaluating combining radiation therapy with immunotherapy for metastatic and stage IV squamous cell carcinomas of the head and…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Phase II Clinical Study to Evaluate HLX43 in Subjects With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase II clinical trial evaluating HLX43 for recurrent or metastatic head and neck squamous cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: HN-QUEST: A Study of Head and Neck Imaging Biomarkers [NA]
The HN-QUEST study investigates imaging biomarkers for head and neck squamous cell carcinoma. The trial is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer [Phase 1]
A Phase 1 clinical trial evaluating STRO-004 in adults with refractory or recurrent metastatic cancer is currently recruiting, investigating…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Evaluating 111In Panitumumab for Nodal Staging in Head and Neck Cancer [Phase 1]
Phase 1 clinical trial evaluating indium-111 labeled panitumumab for nodal staging in head and neck squamous cell carcinoma; the study is cu…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer [Phase 1]
Phase 1 trial evaluating TMV vaccine therapy alone and with pembrolizumab for recurrent/metastatic head and neck squamous cell carcinoma; cu…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Study Comparing Two Immunotherapy Options for Human Papillomavirus Positive HPV-Positive Head and Neck Cancer After Treatment [Phase 2]
This clinical trial update describes a Phase 2 study comparing two immunotherapy options in patients with HPV-positive head and neck cancer …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck Cancer [Phase 1]
Phase 1 dosing study evaluating radiation in combination with tislelizumab and pamiparib in previously treated head and neck cancer is curre…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Impact of Early Response to First-line Anti-PD-1 Monotherapy in Patients With Recurrent and/or Metastatic (R/M) Head and Neck Squamous Cell Carcinoma, Assessed by 18F-FDG PET/CT
This clinical trial is evaluating whether early response to first-line anti-PD-1 monotherapy in recurrent/metastatic head and neck squamous …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Phase II Study of Daily Adaptive Radiotherapy for Submandibular Gland-sparing in Head and Neck Cancer [NA]
This clinical trial update describes a Phase II study of daily adaptive radiotherapy to spare the submandibular gland during treatment of he…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Trial of Cemiplimab, or Cemip-Chemo Followed by Biomarker-guided Treatment for Pts w/HPV H&N Ca [Phase 2]
Phase 2 clinical trial update for cemiplimab, with or without chemotherapy, followed by biomarker-guided treatment in HPV-related head and n…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: First in Human Study of TUB-030 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
First-in-human study of TUB-030 is underway in patients with advanced solid tumors, including head and neck squamous cell carcinoma, small c…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN). [Phase 2]
Phase 2 trial evaluating neoadjuvant pembrolizumab with IO102-103 for head and neck squamous cell carcinoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Iparomlimab and Tuvonralimab Plus Hypofractionated Radiotherapy and Chemotherapy for HAHNSCC [Phase 2]
This Phase 2 clinical trial update describes evaluating Iparomlimab and Tuvonralimab together with hypofractionated radiotherapy and chemoth…