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CLINICAL_TRIALS research · 2026-03-20

Clinical Trial Update: H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC) [Phase 2]

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Summary

Phase 2 trial exploring neoadjuvant XL-092 (zanzalintinib) with pembrolizumab (Keytruda) for surgically resectable, HPV-negative oral cavity squamous cell carci…

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Diseases / indications

Drugs mentioned

  • KEYTRUDA (PEMBROLIZUMAB)
  • XL-092 (zanzalintinib)

Snippet

Sponsor: UNC Lineberger Comprehensive Cancer Center | Conditions: Oral Cavity Squamous Cell Carcinoma, Head and Neck Cancer | Phase 2 | Status: NOT_YET_RECRUITING