Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Cetuximab Combined With Pembrolizumab or Finotonlimab and Chemotherapy in R/M HNSCC [Phase 3]
A Phase 3 trial update evaluating cetuximab with pembrolizumab or finotonlimab plus chemotherapy in recurrent/metastatic head and neck squam…
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CLINICAL_TRIALS other · 2026-04-03Clinical Trial Update: Comparing Cisplatin Every Three Weeks to Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer [Phase 2, Phase 3]
NRG Oncology reports suspension of a phase 2/3 trial comparing cisplatin dosing every three weeks versus weekly when given with radiation fo…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Study of Surzebiclimab (BGB-A425) and Alcestobart (LBL-007) in Combination With Tislelizumab in Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/Phase 2 trial results for the combination of Surzebiclimab (BGB-A425) and Alcestobart (LBL-007) with tislelizumab in advanced solid …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial of ZM008, an anti-LLT1 antibody, given as a single agent and then in combination with toripalimab in patients with ad…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours [Phase 1]
Clinical trial update describes a Phase 1 dose-escalation study of [225Ac]-FPI-2068 in adults with advanced solid tumors, currently recruiti…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Hypofractionated Radiotherapy for Postoperative Intermediate-Risk Head and Neck Squamous Cell Carcinoma [NA]
Clinical trial update on hypofractionated radiotherapy as postoperative treatment for intermediate-risk head and neck squamous cell carcinom…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Study of Adaptive Radiotherapy of Head-neck Cancer Using Daily Replanning and Optimization of the Treatment Plan. [NA]
An ongoing study evaluating adaptive radiotherapy for head and neck squamous cell carcinoma using daily replanning and optimization of the t…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus Pembrolizumab for the Treatment of SCCHN [Phase 3]
A Phase 3 clinical trial compares Ivonescimab alone or Ivonescimab with Ligufalimab versus Pembrolizumab for head and neck squamous cell car…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-08046032 in People With Advanced Cancers [Phase 1]
Phase 1 clinical trial update for PF-08046032 in people with advanced cancers; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC [Phase 2]
Phase 2 clinical trial evaluating adaptive radiotherapy boost for head and neck squamous cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: TBio-4101 and Pembro wi/ or w/o Chemo in Recurrent/Metastatic HNSCC [Phase 1]
A Phase 1 clinical trial update for TBio-4101 with pembrolizumab, with or without chemotherapy, in recurrent or metastatic head and neck squ…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types [Phase 1]
IDEAYA Biosciences is conducting a Phase 1 study of IDE034 in adults with multiple locally advanced or metastatic solid tumors; the trial is…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Neoadjuvant Sacituzumab Govitecan Plus Tagitanlimab for Resectable Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 neoadjuvant trial is evaluating sacituzumab govitecan in combination with Tagitanlimab for resectable head and neck squamous cell …
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients [Phase 3]
This update describes a Phase 3 trial evaluating Petosemtamab versus investigator's choice monotherapy in previously treated head and neck s…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours [Phase 1, Phase 2]
Ipsen is conducting a Phase 1/2 trial of IPN01194 as a single-agent therapy for adults with advanced solid tumors, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Ramucirumab and Pembrolizumab vs Pembrolizumab Monotherapy in PD-L1 Positive Head and Neck Squamous-Cell Carcinoma [Phase 2]
Phase 2 trial compares ramucirumab plus pembrolizumab versus pembrolizumab alone in PD-L1 positive recurrent or metastatic head and neck squ…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCC [Phase 2, Phase 3]
Ongoing Phase 2/Phase 3 trial evaluating INBRX-106 in combination with pembrolizumab as first-line therapy for PD-L1 CPS≥20 head and neck sq…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Multicentric Comparative Study Between a Conventional and an Intensive Follow up Strategy After Treatment of a Head and Neck Squamous Cell Carcinoma [Phase 3]
Phase 3 multicenter trial comparing conventional versus intensive follow-up after treatment of head and neck squamous cell carcinoma; curren…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer [Phase 1]
This clinical trial update notes a Phase 1 study evaluating cemiplimab in combination with chemotherapy and immunotherapy for head and neck …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy [EARLY_Phase 1]
This is a pilot early-phase imaging trial evaluating the HER2-targeted PET tracer [68Ga]Ga-ABY-025 in patients undergoing HER2-targeted ther…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating Nanrilkefusp alfa alone and with pembrolizumab in adults with advanced or metastatic solid tumors; the study (NCT04…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-Line Treatment in Participants With PD-L1-Positive (CPS ≥ 1) Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 2]
A Phase 2 study evaluating the combination of retinfanlimab with INCAGN02385 and INCAGN02390 as first-line therapy for PD-L1-positive recurr…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes ongoing Phase 1/2 studies of the radiopharmaceutical 177Lu-BetaBart. The trial is evaluating its use in…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Neoadjuvant Ficerafusp Alfa With Pembrolizumab in Resectable SCC [Phase 2]
Phase 2 neoadjuvant trial evaluating ficerafusp alfa with pembrolizumab in resectable head and neck squamous cell carcinoma is currently rec…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer [Phase 2]
Phase II trial evaluating neoadjuvant chemotherapy alone or with the PRGN-2009 immunotherapy vaccine for newly diagnosed HPV-associated orop…