Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Digital Health Intervention to Promote Quality of Life in Adults With Chronic Graft Versus Host Disease [NA]
A clinical trial update on a digital health intervention aimed at improving quality of life for adults with chronic graft-versus-host diseas…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Dietary Manipulation of the Microbiome-metabolomic Axis for Mitigating GVHD in Allo HCT Patients [Phase 2]
This clinical trial update reports the completion of a Phase 2 study evaluating dietary modification of the microbiome–metabolomic axis to m…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Ruxolitinib, Human Chorionic Gonadotropin (uhCG/EGF), and Dose De-escalated Corticosteroids [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating ruxolitinib, human chorionic gonadotropin, and dose-de-escalated corticosteroids for acute graft-ve…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease
An observational study sponsored by Incyte Corporation is enrolling patients at risk for chronic graft-versus-host disease (cGVHD) to observ…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: MAGIC Ruxolitinib for aGVHD [Phase 2]
Phase 2 clinical trial investigating ruxolitinib for acute graft-versus-host disease in patients undergoing allogeneic bone marrow transplan…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy [Phase 3]
A Phase 3 clinical trial is evaluating Axatilimab for chronic graft-versus-host disease in participants who have received at least two prior…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Evaluation of the Impact of Reduced Immunosuppression
A completed clinical trial evaluating the outcomes of reducing immunosuppression in patients with graft-versus-host disease.
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease [Phase 2]
Phase 2 clinical trial update evaluating the safety and efficacy of Axatilimab in combination with ruxolitinib for newly diagnosed chronic g…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Chronic GVHD Response Measures Validation
This clinical trial update validates measures used to assess response in chronic graft-versus-host disease.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation [Phase 1, Phase 2]
This Phase 1/2 trial is evaluating the lowest effective dose of post-transplant cyclophosphamide in combination with sirolimus and mycopheno…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: IL6-receptor Inhibitor Iwith Belumosudil for the Treatment of Belumosudil-refractory cGVHD [Phase 1]
A Phase 1 clinical trial update describes testing belumosudil in combination with an IL-6 receptor inhibitor for belumosudil-refractory chro…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Improvement of Women's Health After Allogeneic Stem Cell Transplantation
Clinical trial update indicating recruiting status for a study on improving women's health after allogeneic stem cell transplantation, with …
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Precision Diagnostics in Inflammatory Bowel Disease, Cellular Therapy and Transplantation (The PREDICT Trial)
A clinical trial update for the PREDICT trial at Boston Children's Hospital, focusing on precision diagnostics in inflammatory bowel disease…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Ex Vivo-Expanded Regulatory T Cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic GVHD [Phase 1]
Phase 1 trial evaluating ex vivo-expanded regulatory T cells plus low-dose interleukin-2 for steroid-refractory chronic graft-versus-host di…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: SYN-004 Safety and Tolerability in Allo-HCT Subjects [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating safety and tolerability of SYN-004 in adults undergoing allogeneic hematopoietic stem cell transplantation,…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Gecacitinib in the Treatment of Steroid-Refractory/Dependent Chronic Graf Versus Host Disease (cGVHD). [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating gecacitinib for steroid-refractory or dependent chronic graft-versus-host disease (cGVHD) in HSCT patien…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: CINC424A2X01B Rollover Protocol [Phase 4]
Phase 4 rollover protocol for CINC424A2X01B is active but not recruiting, spanning Primary Myelofibrosis, Polycythemia Vera, Graft-versus-ho…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: A Phase Ib Clinical Study of AC-003 Capsules in Subjects With aGVHD. [Phase 1]
This document provides an update on a Phase 1 clinical trial evaluating AC-003 capsules for acute graft-versus-host disease, currently recru…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease
This clinical trial update describes a study using dendritic cell therapy in patients with acute or chronic skin graft-versus-host disease (…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation
This clinical trial update describes a study evaluating the kinetics of immune cells in blood and tissues affected by chronic graft-versus-h…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: De-escalated Cyclophosphamide (PTCy) and Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis [Phase 2]
Phase 2 study exploring de-escalated post-transplant cyclophosphamide (PTCy) combined with ruxolitinib for GVHD prophylaxis; the trial is cu…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Fecal Microbiota Transplant and Dietary Fiber Supplementation for the Treatment of Gut Graft Versus Host Disease [Phase 1]
Phase 1 clinical trial investigating fecal microbiota transplant and dietary fiber for treating intestinal graft-versus-host disease. The tr…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial [NA]
A clinical trial update for the RESTART trial assessing the impact of exercise on corticosteroid-related complications in patients with graf…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation
This clinical trial is currently recruiting to study diagnosis methods and microbiome factors in vulvovaginal graft-versus-host disease, a G…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Tacrolimus Toothpaste for Management of Oral Chronic Graft vs. Host Disease (cGVHD) [Phase 1]
A Phase 1 clinical trial evaluating tacrolimus toothpaste for managing oral chronic graft-versus-host disease has completed.