Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma [Phase 2]
An ongoing Phase 2 study evaluating maintenance therapy with ruxolitinib after hematopoietic stem cell transplant in patients with T-cell ly…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Clinical Study Evaluating the Safety and Efficacy of GT729 Universal Cell Injection in the Treatment of Refractory or Relapsed Chronic Graft-versus-host Disease (cGVHD) [EARLY_Phase 1]
A Phase 1 clinical study evaluating the safety and efficacy of GT729 Universal Cell Injection for refractory or relapsed chronic graft-versu…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls
This clinical trial update describes a study examining chronic graft-versus-host disease in the oral cavity after allogeneic hematopoietic s…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256) [Phase 2]
Phase 2 pediatric study comparing Axatilimab to Best Available Therapy for chronic graft-versus-host disease after at least two prior system…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Trial of Efficacy and Safety of MC0518 Versus Best Available Therapy in Participants With Steroid-Refractory Acute Graft Versus Host Disease [Phase 2]
A Phase 2 clinical trial is evaluating MC0518 versus best available therapy in participants with steroid-refractory acute graft-versus-host …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Feasibility Study Using CLINIMACS® for Alpha/Beta T-Cell Depletion in Stem Cell Transplant [NA]
A feasibility study evaluating CLINIMACS for alpha/beta T-cell depletion in stem cell transplantation to reduce graft-versus-host disease.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Vorinostat for Graft-versus-host Disease (GVHD) Prevention in Non-Malignant Adolescent and Young Adults (AYA) Population [Phase 2]
A Phase 2 clinical trial evaluating vorinostat for prevention of graft-versus-host disease in non-malignant adolescent and young adult patie…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Long-term Extension Study of PCI-32765 (Ibrutinib) [Phase 3]
Phase 3 long-term extension study of ibrutinib (PCI-32765) in chronic lymphocytic leukemia/small lymphocytic lymphoma and other B-cell malig…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Study of Belumosudil in People at Risk of Developing Graft-Versus-Host Disease After a Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating belumosudil for people at risk of graft-versus-host disease after stem cell transplant is currently recrui…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Horizons Chronic Graft-Versus-Host-Disease Study [NA]
This is a status update for a University of Miami study on chronic graft-versus-host disease, currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Diagnostic Refinement and Educational Approaches in Managing Bone Marrow Transplantation [NA]
This clinical trial update describes diagnostic refinement and educational approaches being studied to manage graft-versus-host disease and …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy [Phase 2]
A Phase 2 clinical trial comparing ruxolitinib to prednisone as first-line systemic therapy for chronic graft-versus-host disease (cGVHD) is…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease [Phase 3]
A Phase 3 clinical trial is evaluating axatilimab plus corticosteroids as initial treatment for chronic graft-versus-host disease; the study…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK) [Phase 2]
A Phase 2 clinical trial of belumosudil in children with chronic graft-versus-host disease is currently recruiting in the schoolROCK study.
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Tele-Palliative Care Intervention for Patients With Chronic Graft-Versus-Host Disease [NA]
This ClinicalTrials.gov entry notes an active, not recruiting study at Massachusetts General Hospital evaluating a tele-palliative care inte…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Novel Therapies for Severe Acute GVHD (Graft-versus-host Disease) [Phase 2]
This update reports a Phase 2 clinical trial investigating novel therapies for severe acute graft-versus-host disease, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Allogeneic HSCT With Low-Dose Post-Transplant Cyclophosphamide for GVHD Prevention [Phase 2]
A Phase 2 clinical trial is evaluating low-dose post-transplant cyclophosphamide after allogeneic stem cell transplantation to prevent graft…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease [Phase 1]
This clinical trial update reports completion of a Phase 1 study evaluating CD40-L blockade to prevent acute graft-versus-host disease.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Endothelial Dysfunction as a Predictive Marker of Acute Graft-Versus-Host Disease in Adult Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
A completed clinical trial evaluated endothelial dysfunction as a predictive biomarker for acute graft-versus-host disease in adults undergo…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Evaluation of Patients With Immune Function Abnormalities
The NIAID-sponsored study evaluating patients with immune function abnormalities (chronic granulomatous disease, X-linked severe combined im…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating photobiomodulation therapy for oral graft-versus-host disease in patients after stem cell transplantation;…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Evaluation of Allogenic Mesenchymal Stem Cell (MSC) Injection Therapy for Refractory Graft-versus-Host Disease (GVHD) Unresponsive to Conventional Treatments [Phase 2]
Phase 2 clinical trial evaluating donor-derived allogeneic mesenchymal stem cell injections for refractory graft-versus-host disease. The st…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Axatilimab for Sclerotic Chronic Graft-versus-Host Disease [Phase 2]
Phase 2 clinical trial update for Axatilimab in sclerotic chronic graft-versus-host disease. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) [Phase 1, Phase 2]
Phase I/II clinical trial evaluating pacritinib, a JAK2/IRAK1/CSF1R inhibitor, in patients with refractory chronic graft-versus-host disease…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Trial to Evaluate the Safety and Preliminary Efficacy of iMesenchymal Stromal Cells(iMSC) in Subjects With SR-aGVHD [NA]
This clinical trial registry entry describes an ongoing study evaluating the safety and preliminary efficacy of iMesenchymal Stromal Cells (…