Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives
This update describes improved methods for selecting donor cells used in bone marrow transplant alternatives, and the trial is currently rec…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease [NA]
This clinical trial investigates whether routine dental cleaning can help prevent chronic graft-versus-host disease in patients undergoing h…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Ruxolitinib With and Without CTLA-4 Ig Abatacept for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation [Phase 1]
A Phase 1 clinical trial is evaluating ruxolitinib with and without abatacept (CTLA-4Ig) for prophylaxis of graft-versus-host disease and cy…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Prebiotic Galacto-oligosaccharide and Acute GVHD [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating galacto-oligosaccharide as a prebiotic for acute graft-versus-host disease is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Pediatric cGVHD Symptom Scale
A pediatric clinical trial update describes a study evaluating a symptom scale for graft-versus-host disease in children, with recruitment o…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation [Phase 1, Phase 2]
This clinical trial update reports on a Phase 1/2 study of alvelestat (MPH966), an oral neutrophil elastase inhibitor, for bronchiolitis obl…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Establishment of Biomarker Panel For Forecasting Chronic Graft-Versus-Host Disease (cGVHD) After Allo-HSCT [NA]
This document reports a clinical trial update on developing a biomarker panel to forecast chronic graft-versus-host disease following alloge…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease
This ClinicalTrials.gov study is an ongoing natural history study to identify clinical and biological factors that determine outcomes in chr…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Improving Outcomes Assessment in Chronic GVHD
This ClinicalTrials.gov entry describes a study aimed at improving outcome assessment in chronic graft-versus-host disease, with the trial c…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants
This clinical trial update describes a long-term evaluation and follow-up care program for patients who received stem cell transplants.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease [EARLY_Phase 1]
An early Phase 1 clinical trial evaluating the addition of cord blood–derived mesenchymal stromal cells to ruxolitinib for treating steroid-…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT [Phase 1]
Stanford is conducting a Phase 1 study evaluating cessation of tacrolimus immunosuppression after allogeneic hematopoietic cell transplantat…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Itacitinib for the Prevention of Graft Versus Host Disease [Phase 2]
Phase 2 clinical trial evaluating Itacitinib to prevent graft-versus-host disease after hematopoietic stem cell transplantation is active bu…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203) [Phase 3]
This Phase 3 randomized trial compares tacrolimus/methotrexate/ruxolitinib versus post-transplant cyclophosphamide/tacrolimus/mycophenolate …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Pilot Study to Correlate 4-18F- Fluoro-1-naphthol 18F-4FN PET/CT Imaging With Chronic Graft Versus Host Disease Manifestations [Phase 2]
This is a Phase 2 pilot study at MD Anderson evaluating whether PET/CT imaging with the tracer 18F-4FN correlates with manifestations of chr…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma [Phase 2]
An ongoing Phase 2 study evaluating maintenance therapy with ruxolitinib after hematopoietic stem cell transplant in patients with T-cell ly…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Clinical Study Evaluating the Safety and Efficacy of GT729 Universal Cell Injection in the Treatment of Refractory or Relapsed Chronic Graft-versus-host Disease (cGVHD) [EARLY_Phase 1]
A Phase 1 clinical study evaluating the safety and efficacy of GT729 Universal Cell Injection for refractory or relapsed chronic graft-versu…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls
This clinical trial update describes a study examining chronic graft-versus-host disease in the oral cavity after allogeneic hematopoietic s…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256) [Phase 2]
Phase 2 pediatric study comparing Axatilimab to Best Available Therapy for chronic graft-versus-host disease after at least two prior system…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Trial of Efficacy and Safety of MC0518 Versus Best Available Therapy in Participants With Steroid-Refractory Acute Graft Versus Host Disease [Phase 2]
A Phase 2 clinical trial is evaluating MC0518 versus best available therapy in participants with steroid-refractory acute graft-versus-host …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Feasibility Study Using CLINIMACS® for Alpha/Beta T-Cell Depletion in Stem Cell Transplant [NA]
A feasibility study evaluating CLINIMACS for alpha/beta T-cell depletion in stem cell transplantation to reduce graft-versus-host disease.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Vorinostat for Graft-versus-host Disease (GVHD) Prevention in Non-Malignant Adolescent and Young Adults (AYA) Population [Phase 2]
A Phase 2 clinical trial evaluating vorinostat for prevention of graft-versus-host disease in non-malignant adolescent and young adult patie…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Long-term Extension Study of PCI-32765 (Ibrutinib) [Phase 3]
Phase 3 long-term extension study of ibrutinib (PCI-32765) in chronic lymphocytic leukemia/small lymphocytic lymphoma and other B-cell malig…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Horizons Chronic Graft-Versus-Host-Disease Study [NA]
This is a status update for a University of Miami study on chronic graft-versus-host disease, currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Diagnostic Refinement and Educational Approaches in Managing Bone Marrow Transplantation [NA]
This clinical trial update describes diagnostic refinement and educational approaches being studied to manage graft-versus-host disease and …