Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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FDA approval · 2013-09-27FDA Approved: CELLCEPT — Supplemental Application (Genentech, Inc.)
The FDA approved a supplemental application for CELLCEPT (mycophenolate mofetil) submitted by Genentech.
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FDA approval · 2013-09-27FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (Accord Healthcare Inc.)
FDA approved a supplemental application for MYCOPHENOLATE MOFETIL by Accord Healthcare Inc., marking an update to its regulatory status rela…
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CLINICAL_TRIALS research · 2013-09-13Clinical Trial Update: Mesenchymal Stem Cells Infusion for aGVHD Prophylaxis Transplantation [Phase 2]
Phase 2 clinical trial evaluating mesenchymal stem cell infusion to prevent acute graft-versus-host disease in transplant patients; current …
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CLINICAL_TRIALS research · 2013-08-26Clinical Trial Update: T-Lymphocyte Infusion or Standard Therapy in Treating Patients at Risk of Cytomegalovirus Infection After a Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial comparing T-lymphocyte infusion versus standard therapy to prevent cytomegalovirus infection in patients after donor …
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CLINICAL_TRIALS research · 2013-08-26Clinical Trial Update: Early Diagnosis of Aspergillosis in Patients at High Risk of Fungal Infection Caused by Treatment for Hematologic Cancer or Other Disease [NA]
A clinical trial update on early diagnostic methods for aspergillosis in patients at high risk due to treatment for hematologic cancers or o…
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CLINICAL_TRIALS trial_result · 2013-08-13Clinical Trial Update: Alefacept in Subjects With Steroid-Refractory Chronic Graft-versus-Host Disease [Phase 2]
A Phase 2 trial of alefacept for steroid-refractory chronic graft-versus-host disease was terminated, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-08-09Clinical Trial Update: Campath in Chronic GVHD [Phase 1]
A Phase 1 study of Campath (alemtuzumab) for chronic graft-versus-host disease; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-07-10Clinical Trial Update: Treatment of Bone Marrow to Prevent Graft-Versus-Host Disease in Patients With Acute or Chronic Leukemia Undergoing Bone Marrow Transplantation [Phase 2, Phase 3]
This document summarizes Phase 2 and Phase 3 clinical trials evaluating a treatment aimed at preventing graft-versus-host disease in patient…
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CLINICAL_TRIALS trial_result · 2013-06-12Clinical Trial Update: Rituximab Therapy for Steroid-Refractory Chronic Graft Versus Host Disease [Phase 1, Phase 2]
A Phase 1/2 trial evaluated Rituximab for steroid-refractory chronic graft-versus-host disease; the study has completed.
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CLINICAL_TRIALS trial_result · 2013-05-30Clinical Trial Update: Beclomethasone Plus Prednisone in Treating Patients With Graft-Versus-Host Disease [Phase 3]
This Clinical Trial Update reports the completion of a Phase 3 study evaluating the combination of beclomethasone and prednisone for graft-v…
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CLINICAL_TRIALS withdrawal · 2013-05-14Clinical Trial Update: Chronic Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant
A clinical trial evaluating chronic graft-versus-host disease after allogeneic donor stem cell transplantation in cancer patients has been t…
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX [NA]
This trial compared tacrolimus plus mycophenolate mofetil to tacrolimus plus methotrexate for GVHD prophylaxis. It completed and posted resu…
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CLINICAL_TRIALS trial_result · 2013-03-14Clinical Trial Update: T&B Depletion Non Malignant [Phase 2]
Phase 2 clinical trial update for T&B depletion in non-malignant graft-versus-host disease, with the trial status currently unknown.
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CLINICAL_TRIALS trial_result · 2013-03-13Clinical Trial Update: The Use of Etanercept (Enbrel®) in the Treatment of Acute Graft-Versus-Host Disease [Phase 2]
A Phase 2 clinical trial evaluating etanercept (Enbrel) for the treatment of acute graft-versus-host disease has completed.
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CLINICAL_TRIALS withdrawal · 2013-02-13Clinical Trial Update: A Study of Panobinostat (LBH589) as Second-Line Therapy in Patients With Chronic Graft-Versus-Host Disease [Phase 2]
Phase 2 trial of panobinostat (LBH589) as second-line therapy for chronic graft-versus-host disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-01-10Clinical Trial Update: Mesenchymal Stem Cells for Treatment of Refractory Chronic Graft-versus-host Disease [Phase 2]
This clinical trial update describes a Phase 2 study evaluating mesenchymal stem cells for treatment of refractory chronic graft-versus-host…
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CLINICAL_TRIALS other · 2013-01-10Clinical Trial Update: Mesenchymal Stem Cells for Treatment of Refractory Acute Graft-versus-host Disease [Phase 2]
Clinical trial update for a Phase 2 study using mesenchymal stem cells to treat refractory acute graft-versus-host disease; current status i…
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CLINICAL_TRIALS research · 2013-01-09Clinical Trial Update: Mesenchymal Stromal Cells (MSCs) for the Treatment of Graft Versus Host Disease (GVHD) [Phase 1]
An update on a Phase 1 trial evaluating mesenchymal stromal cells for the treatment of graft-versus-host disease; the current status is UNKN…
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CLINICAL_TRIALS trial_result · 2012-12-11Clinical Trial Update: Removal of T Cells to Prevent Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation [Phase 2]
This update reports the termination of a Phase 2 clinical trial investigating removal of T cells to prevent graft-versus-host disease in bon…
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CLINICAL_TRIALS trial_result · 2012-10-03Clinical Trial Update: Clinical Trial With Clobetasol and Dexamethasone for Topical Treatment of Oral Lesions of Chronic Graft-versus-host Disease [Phase 3]
Phase 3 completed clinical trial evaluating topical clobetasol and dexamethasone for oral lesions in chronic graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2012-09-11Clinical Trial Update: Safety and Efficacy of Cannabidiol for Grade I/II Acute Graft Versus Host Disease (GVHD) After Allogeneic Stem Cell Transplantation [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety and efficacy of cannabidiol for grade I/II acute graft-versus-host disease after allogeneic stem cell tran…
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CLINICAL_TRIALS trial_result · 2012-08-03Clinical Trial Update: Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Chronic Graft Versus Host Disease [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating the efficacy and safety of allogeneic mesenchymal stem cells for chronic graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2012-08-02Clinical Trial Update: Phase I/II Trial rHuKFG for the Treatment of Steroid Refractory Gastrointestinal Acute GVHD [Phase 1, Phase 2]
This is a Phase I/II trial update for recombinant human keratinocyte growth factor (rHuKFG) aimed at treating steroid-refractory gastrointes…
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CLINICAL_TRIALS trial_result · 2012-07-31Clinical Trial Update: Feasibility Study of Collecting Multicenter Chronic GVHD Data
This document reports the completion of a multicenter feasibility study evaluating the collection of chronic graft-versus-host disease data.
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CLINICAL_TRIALS research · 2012-07-30Clinical Trial Update: Experience of Having Chronic Graft-Versus-Host Disease
A clinical trial update describing the experiences of patients with chronic graft-versus-host disease.