Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Study of Opebacan in Patients Undergoing Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) [Phase 1, Phase 2]
A Phase 1/2 study of Opebacan for graft-versus-host disease in patients undergoing myeloablative allogeneic hematopoietic stem cell transpla…
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CLINICAL_TRIALS trial_result · 2012-07-19Clinical Trial Update: Safety Study of Homeo-GH (Bone Marrow Derived Clonal Mesenchymal Stem Cell) to Treat Acute/Chronic Graft Versus Host Disease (GVHD) [Phase 1]
Phase 1 safety study of Homeo-GH, a bone marrow–derived clonal mesenchymal stem cell therapy, for acute and chronic graft-versus-host diseas…
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CLINICAL_TRIALS withdrawal · 2012-07-09Clinical Trial Update: Rituximab for GVHD [Phase 2]
Phase 2 trial of Rituximab for graft-versus-host disease has been withdrawn.
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FDA approval · 2012-06-21FDA Approved: JAKAFI — Supplemental Application (Incyte Corporation)
The FDA approved a supplemental application for JAKAFI (ruxolitinib) submitted by Incyte Corporation.
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CLINICAL_TRIALS trial_result · 2012-06-04Clinical Trial Update: Stem Cell Transplantation in Treating Patients With Hematologic Cancer [Phase 1]
Phase 1 trial update evaluating stem cell transplantation as treatment for hematologic cancers. The study includes patients with various hem…
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CLINICAL_TRIALS trial_result · 2012-06-01Clinical Trial Update: Bone Marrow and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer [Phase 1]
Phase 1 clinical trial update on bone marrow and peripheral stem cell transplantation for patients with hematologic cancers; the study statu…
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CLINICAL_TRIALS trial_result · 2012-05-28Clinical Trial Update: G-CSF-Treated Donor Bone Marrow Transplant in Treating Patients With Hematologic Disorders [NA]
Clinical trial update for a study evaluating G-CSF–treated donor bone marrow transplant in hematologic disorders; the trial (NCT00253552) is…
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CLINICAL_TRIALS research · 2012-05-10Clinical Trial Update: PETCT for Diagnosing and Monitoring Acute GVHD
A clinical trial update from Rabin Medical Center investigates PET/CT imaging to diagnose and monitor acute graft-versus-host disease, with …
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CLINICAL_TRIALS research · 2012-03-16Clinical Trial Update: Umbilical Cord Blood-derived Mesenchymal Stem Cells for the Treatment of Steroid-refractory Acute or Chronic Graft-versus-host-disease [Phase 1, Phase 2]
This clinical trial update reports on the use of umbilical cord blood-derived mesenchymal stem cells to treat steroid-refractory acute or ch…
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CLINICAL_TRIALS trial_result · 2012-03-13Clinical Trial Update: Research Study of Visilizumab for Treatment of Acute Graft Versus Host Disease [Phase 1, Phase 2]
This update reports the completion of a Phase 1/2 study evaluating Visilizumab for the treatment of acute graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2012-03-08Clinical Trial Update: Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation [Phase 2]
This is a Phase 2 clinical trial update evaluating tacrolimus, sirolimus, and methotrexate as prophylaxis for graft-versus-host disease afte…
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CLINICAL_TRIALS trial_result · 2012-01-26Clinical Trial Update: Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation [Phase 2]
A Phase 2 study evaluating sirolimus with tacrolimus for graft-versus-host disease prophylaxis after unrelated donor stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2012-01-23Clinical Trial Update: Thymoglobulin (ATG) Dose Finding Study [Phase 1, Phase 2]
A Phase 1/2 dose-finding study of Thymoglobulin (ATG) for graft-versus-host disease was terminated.
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CLINICAL_TRIALS trial_result · 2011-12-12Clinical Trial Update: Acute Graft-Versus-Host Disease (aGvHD) Prophylaxis With ATG-Fresenius in Matched Unrelated Donor-Stem Cell Transplantation (MUD-SCT) [Phase 3]
Phase 3 clinical trial evaluating ATG-Fresenius for preventing acute graft-versus-host disease in matched unrelated donor stem cell transpla…
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CLINICAL_TRIALS trial_result · 2011-11-30Clinical Trial Update: Graft-Versus-Host Disease Prevention in Treating Patients Who Are Undergoing Bone Marrow Transplantation [Phase 3]
A Phase 3 clinical trial evaluating strategies to prevent graft-versus-host disease in patients undergoing bone marrow transplantation has c…
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CLINICAL_TRIALS trial_result · 2011-09-07Clinical Trial Update: A Study of Rituximab Combined With Prednisone for the Initial Treatment of Chronic Graft Versus Host Disease (cGVHD) [Phase 2]
A Phase 2 study evaluating rituximab in combination with prednisone as initial therapy for chronic graft-versus-host disease has been termin…
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CLINICAL_TRIALS trial_result · 2011-07-15Clinical Trial Update: Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluated sirolimus, tacrolimus, and methotrexate to prevent acute graft-versus-host disease in patients with he…
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CLINICAL_TRIALS trial_result · 2011-05-26Clinical Trial Update: Cord Blood Serum in the Treatment of Ocular Surface Diseases
A completed clinical trial assessing cord blood serum for ocular surface diseases, including graft-versus-host disease affecting the eye and…
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CLINICAL_TRIALS trial_result · 2011-03-08Clinical Trial Update: Study Comparing Cyclosporine Dose Reduction vs. Cyclosporine Elimination in Kidney Transplant Recipients Taking Sirolimus [Phase 4]
A Phase 4 study comparing reducing cyclosporine dose versus eliminating cyclosporine in kidney transplant recipients treated with sirolimus …
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CLINICAL_TRIALS trial_result · 2011-03-08Clinical Trial Update: Compassionate Use of Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Gastrointestinal Tract [NA]
Clinical trial update reporting on compassionate use of beclomethasone for graft-versus-host disease affecting the gastrointestinal tract; t…
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CLINICAL_TRIALS trial_result · 2011-03-07Clinical Trial Update: Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer [Phase 2]
Phase 2 clinical trial evaluating chemotherapy, radiation therapy, and umbilical cord blood transplantation in patients with hematologic can…
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CLINICAL_TRIALS trial_result · 2011-03-07Clinical Trial Update: Thalidomide in Treating Patients With Chronic Graft-Versus-Host Disease Following Bone Marrow Transplant [Phase 2]
Phase 2 trial of thalidomide for chronic graft-versus-host disease after bone marrow transplant has completed.
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CLINICAL_TRIALS research · 2011-03-07Clinical Trial Update: Immunologic Diagnostic Blood Test in Predicting Side-Effects in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Other Diseases
This update notes termination of a clinical trial evaluating an immunologic diagnostic blood test intended to predict donor stem cell transp…
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CLINICAL_TRIALS trial_result · 2011-03-07Clinical Trial Update: Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases [Phase 2]
A Phase 2 clinical trial evaluating umbilical cord blood transplantation for hematologic cancers and related diseases has been completed.
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CLINICAL_TRIALS trial_result · 2011-01-25Clinical Trial Update: Evaluation of Antifungal Prophylaxis on Graft-versus-host Disease (GVHD) Patients [Phase 4]
A Phase 4 clinical trial evaluating antifungal prophylaxis in patients with graft-versus-host disease has been terminated.