Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-06-04Clinical Trial Update: Study of Etanercept for the Prevention of Complications Resulting From Hematopoietic Stem Cell Transplantation (HSCT) [Phase 2]
A Phase 2 clinical trial assessed etanercept for preventing complications following hematopoietic stem cell transplantation, with results po…
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CLINICAL_TRIALS trial_result · 2014-05-29Clinical Trial Update: Everolimus in Combination With Cyclosporine A and Prednisolone for the Treatment of Graft Versus Host Disease [Phase 1]
Phase 1 trial evaluating everolimus combined with cyclosporine A and prednisolone for graft-versus-host disease; the study status is termina…
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CLINICAL_TRIALS trial_result · 2014-05-05Clinical Trial Update: Graft-Versus-Host Disease (GVHD) Prophylaxis After Allogeneic Peripheral Blood Hematopoietic Cell Transplantation [Phase 2]
Phase 2 trial update reporting results on prophylaxis for acute graft-versus-host disease after allogeneic peripheral blood hematopoietic ce…
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CLINICAL_TRIALS trial_result · 2014-04-17Clinical Trial Update: Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer [Phase 3]
Phase 3 trial update evaluating laboratory-treated donor bone marrow in patients undergoing donor stem cell transplant for hematologic cance…
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CLINICAL_TRIALS trial_result · 2014-04-11Clinical Trial Update: Vorinostat to Prevent Graft Versus Host Disease Following Reduced Intensity, Related Donor Stem Cell Transplant [Phase 1, Phase 2]
This clinical trial update summarizes completed Phase 1/2 results evaluating vorinostat to prevent graft-versus-host disease after reduced-i…
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CLINICAL_TRIALS trial_result · 2014-04-08Clinical Trial Update: Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-myeloablative Peripheral Blood Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating tacrolimus and sirolimus as graft-versus-host disease prophylaxis after allogeneic non-myeloablative peripheral blo…
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CLINICAL_TRIALS trial_result · 2014-04-03Clinical Trial Update: Study of First Line Treatment of Chronic Graft Versus Host Disease With the Association of Ciclosporine, Corticosteroids and Rituximab (Protocol R-GVHD) [Phase 2]
A Phase 2 trial evaluating first-line treatment of chronic graft-versus-host disease with ciclosporine, corticosteroids, and rituximab has c…
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CLINICAL_TRIALS trial_result · 2014-04-02Clinical Trial Update: Palifermin in Preventing Chronic Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer [NA]
This clinical-trial update reports completion and results posting for palifermin used to prevent chronic graft-versus-host disease in patien…
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CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: Rituximab for Prevention of Chronic GVHD [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating rituximab for the prevention of chronic graft-versus-host disease has completed with results posted in 2…
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CLINICAL_TRIALS trial_result · 2014-03-17Clinical Trial Update: Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies [Phase 1]
A Phase 1 study of minor histocompatibility vaccination after allogeneic stem cell transplantation for advanced hematologic malignancies has…
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CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: Sibling Donor Peripheral Stem Cell Transplant or Sibling Donor Bone Marrow Transplant in Treating Patients With Hematologic Cancers or Other Diseases [Phase 3]
Phase 3 trial comparing sibling donor peripheral blood stem cell transplant versus sibling donor bone marrow transplant in hematologic disea…
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CLINICAL_TRIALS trial_result · 2014-02-28Clinical Trial Update: Bortezomib Plus Prednisone for Initial Therapy of Chronic Graft Versus Host Disease [Phase 2]
This phase 2 clinical trial evaluates the use of bortezomib plus prednisone as initial therapy for chronic graft-versus-host disease and rep…
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CLINICAL_TRIALS trial_result · 2014-02-14Clinical Trial Update: Hydroxychloroquine in Treating Patients With Newly Diagnosed Chronic Graft-Versus-Host Disease [Phase 3]
Phase 3 clinical trial evaluating hydroxychloroquine for newly diagnosed chronic graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2014-01-29Clinical Trial Update: Ultra-Low Dose Interleukin-2 for Refractory Chronic Graft Versus Host Disease [Phase 1]
Phase 1 trial update of ultra-low dose interleukin-2 for refractory chronic graft versus host disease has completed with results posted.
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FDA approval · 2014-01-16FDA Approved: CYCLOSPORINE — Supplemental Application (Apotex Corp)
The FDA approved a supplemental application for cyclosporine from Apotex Corp, authorizing changes under the generic product's regulatory fi…
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CLINICAL_TRIALS trial_result · 2013-12-18Clinical Trial Update: Fludarabine in Treating Patients With Steroid-Resistant Chronic Graft- Versus-Host Disease [Phase 1, Phase 2]
This document describes a Phase 1/2 clinical trial evaluating fludarabine for steroid-resistant chronic graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2013-12-13Clinical Trial Update: Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation [Phase 2]
Phase 2 trial evaluating sirolimus, tacrolimus, thymoglobulin, and rituximab as graft-versus-host-disease prophylaxis in haploidentical and …
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CLINICAL_TRIALS trial_result · 2013-12-11Clinical Trial Update: Lenalidomide (Revlimid®) as Second Line Therapy in Patients With Chronic Graft-Vs-Host Disease (GVHD) [Phase 2]
Phase 2 study evaluating lenalidomide (Revlimid) as second-line therapy for chronic graft-versus-host disease was terminated, with results p…
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CLINICAL_TRIALS trial_result · 2013-12-10Clinical Trial Update: Research Study to Determine if an Experimental Agent, LLME Can Decrease the Incidence and Severity of Graft-Versus-Host-Disease (GVHD) Following Blood (Hematopoietic) Stem Cell Transplantation [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluated the experimental agent LLME for reducing the incidence and severity of graft-versus-host disease after…
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CLINICAL_TRIALS trial_result · 2013-12-06Clinical Trial Update: Study of orBec® With Prednisone Therapy in the Treatment of Patients With Graft Versus Host Disease (GVHD) [Phase 3]
A Phase 3 study evaluating orBec in combination with prednisone for graft-versus-host disease was terminated, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-11-28Clinical Trial Update: Study on the Safety and Effectiveness of VELCADE® in the Treatment of Graft-Versus-Host Disease [Phase 2]
A Phase 2 trial evaluating Velcade (bortezomib) for safety and effectiveness in graft-versus-host disease has completed. Results were posted…
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: Rifaximin for Preventing Acute Graft Versus Host Disease (AGVHD) [Phase 1]
Emory University conducted a Phase 1 trial evaluating rifaximin to prevent acute graft-versus-host disease in patients undergoing bone marro…
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CLINICAL_TRIALS trial_result · 2013-10-17Clinical Trial Update: Positron Emission Tomography - Computed Tomography (PET-CT) Scanning in Chronic Graft Versus Host Disease (cGvHD) [NA]
A clinical trial evaluating PET-CT scanning in chronic graft-versus-host disease has been terminated.
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CLINICAL_TRIALS withdrawal · 2013-10-16Clinical Trial Update: Pentostatin, Cyclophosphamide Plus Rituximab (PCR) for the Therapy of Poor-Prognosis Chronic Graft-Versus-Host Disease [Phase 2]
A Phase 2 trial evaluating Pentostatin, Cyclophosphamide, and Rituximab for poor-prognosis chronic graft-versus-host disease has been withdr…
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CLINICAL_TRIALS trial_result · 2013-10-08Clinical Trial Update: Treatment of Refractory Acute Graft-Versus-Host Disease by Sequential Infusion of Allogenic Mesenchymal Stem Cell. [Phase 1, Phase 2]
This update reports the completion of a Phase 1/2 clinical trial evaluating sequential infusion of allogeneic mesenchymal stem cells to trea…