Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: Thymoglobulin to Prevent Acute Graft vs. Host Disease (GvHD) in Patients With Acute Lymphocytic Leukemia (ALL) or Acute Myelogenous Leukemia (AML) Receiving a Stem Cell Transplant [NA]
A completed clinical trial evaluated Thymoglobulin to prevent acute graft-versus-host disease in patients with acute myeloid leukemia or acu…
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CLINICAL_TRIALS withdrawal · 2015-03-06Clinical Trial Update: Prevention of Graft-Versus-Host Disease in Patients With Hematologic Malignancies Who Are Receiving a Bone Marrow Transplant [Phase 1, Phase 2]
A Phase 1/2 clinical trial on preventing graft-versus-host disease in patients with hematologic malignancies undergoing bone marrow transpla…
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CLINICAL_TRIALS withdrawal · 2015-03-02Clinical Trial Update: Lymphocyte Profiles and Activation Status in Patients With Graft-Versus-Host Disease
A clinical trial examining lymphocyte profiles and activation in patients with graft-versus-host disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-02-04Clinical Trial Update: Alemtuzumab Use (MabCampath®) in Hematopoietic Transplant of Unrelated Donor With Reduced Intensity Conditioning [Phase 2]
Phase 2 study of alemtuzumab (MabCampath) in hematopoietic transplantation from an unrelated donor with reduced intensity conditioning was t…
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CLINICAL_TRIALS trial_result · 2015-01-15Clinical Trial Update: Daily IL-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease [Phase 2]
Phase 2 trial evaluating daily interleukin-2 for steroid-refractory chronic graft-versus-host disease; results were posted on 2015-01-15.
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FDA approval · 2014-12-15FDA Approved: JAKAFI — Supplemental Application (Incyte Corporation)
The FDA announced a supplemental application submission for JAKAFI (ruxolitinib) by Incyte, indicating a potential supplemental approval. Th…
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CLINICAL_TRIALS trial_result · 2014-12-04Clinical Trial Update: University of Wisconsin hMSC Cell Bank: Bone Marrow Donor Protocol [NA]
The University of Wisconsin's hMSC bone marrow donor protocol trial (NCT01463475) has completed, involving graft-versus-host disease and acu…
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CLINICAL_TRIALS withdrawal · 2014-12-04Clinical Trial Update: OTI-010 for Graft-Versus-Host Disease Prophylaxis in Treating Patients Who Are Undergoing Donor Peripheral Stem Cell Transplantation for Hematologic Malignancies [Phase 2]
A Phase 2 clinical trial (OTI-010) evaluating prophylaxis against graft-versus-host disease in patients undergoing donor peripheral blood st…
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Treatment of Chronic Graft-Versus-Host Disease With Mesenchymal Stromal Cells [Phase 3]
A Phase 3 trial is investigating mesenchymal stromal cells for chronic graft-versus-host disease. The current status of the trial is unknown…
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CLINICAL_TRIALS research · 2014-11-11Clinical Trial Update: Decidual Stromal Cells as Treatment for Acute Graft Versus Host Disease, a Phase 1-2 Study [Phase 1, Phase 2]
Phase 1-2 clinical trial evaluating decidual stromal cells for the treatment of acute graft-versus-host disease; current status is unknown.
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CLINICAL_TRIALS research · 2014-11-11Clinical Trial Update: A Phase 2 Study Using Placenta Derived Decidual Stromal Cells for Graft Versus Host Disease [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating placenta-derived decidual stromal cells for treating graft-versus-host disease; status not provided.
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CLINICAL_TRIALS trial_result · 2014-11-06Clinical Trial Update: Treatment of Steroid Resistant GVHD by Infusion MSC [Phase 1, Phase 2]
An update on a Phase 1/2 trial evaluating infusion of mesenchymal stem cells to treat steroid-resistant graft-versus-host disease, which has…
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CLINICAL_TRIALS trial_result · 2014-10-21Clinical Trial Update: Sirolimus, Mycophenolate Mofetil and Bortezomib as Graft-Versus-Host Disease (GVHD) Prophylaxis After Reduced Intensity Conditioning (RIC) Hematopoietic Stem Cell Transplantation [Phase 2]
A Phase 2 trial evaluating a sirolimus, mycophenolate mofetil, and bortezomib regimen as graft-versus-host disease prophylaxis after reduced…
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CLINICAL_TRIALS trial_result · 2014-10-09Clinical Trial Update: Low-Dose Prednisone or Methylprednisolone in Treating Patients With Newly Diagnosed Acute Graft-versus-Host Disease [Phase 3]
A Phase 3 trial evaluating low-dose prednisone or methylprednisolone for newly diagnosed acute graft-versus-host disease, with results poste…
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CLINICAL_TRIALS research · 2014-10-02Clinical Trial Update: Biomarkers for Acute Graft-versus-host Disease
A clinical trial update discussing biomarkers for acute graft-versus-host disease, with the current study status listed as unknown.
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CLINICAL_TRIALS trial_result · 2014-09-25Clinical Trial Update: Addition of Etanercept and Extracorporeal Photopheresis (ECP) to Standard Graft-Versus-Host Disease (GVHD) Prophylaxis in Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating addition of etanercept and extracorporeal photopheresis to standard graft-versus-host disease prophylaxis …
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CLINICAL_TRIALS research · 2014-09-16Clinical Trial Update: MSCs Combined With CD25 Monoclonal Antibody and Calcineurin Inhibitors for Treatment of Steroid-resistant aGVHD [Phase 2, Phase 3]
Phase 2/3 trial evaluating mesenchymal stem cells with a CD25 monoclonal antibody and calcineurin inhibitors for steroid-resistant acute gra…
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CLINICAL_TRIALS trial_result · 2014-09-15Clinical Trial Update: Trial to Evaluate Palifermin in the Reduction of Acute Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Allogeneic Marrow/Peripheral Blood Progenitor Cell (PBPC) Transplantation [Phase 2]
Phase 2 trial evaluating palifermin to reduce acute graft-versus-host disease in patients with hematologic malignancies undergoing allogenei…
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CLINICAL_TRIALS trial_result · 2014-08-29Clinical Trial Update: Exploratory Study of Natural Killer Cells in Human Skin [NA]
Clinical trial update indicates completion of an exploratory study of natural killer cells in human skin, covering Atopic dermatitis, Contac…
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CLINICAL_TRIALS research · 2014-08-26Clinical Trial Update: Safety and Efficacy Study of Allogenic Mesenchymal Stem Cells to Treat Extensive Chronic Graft Versus Host Disease [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of allogeneic mesenchymal stem cells for extensive chronic graft-versus-host dis…
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CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer [Phase 2]
This Phase 2 trial tested sirolimus, tacrolimus, and antithymocyte globulin for preventing graft-versus-host disease in patients undergoing …
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CLINICAL_TRIALS trial_result · 2014-08-04Clinical Trial Update: The Use of Etanercept Enbrel as Sole Treatment for Grade I Acute Graft Versus Host Disease [Phase 3]
A Phase 3 trial evaluated etanercept (Enbrel) as the sole treatment for Grade I acute graft-versus-host disease, with results posted in 2014…
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CLINICAL_TRIALS trial_result · 2014-07-09Clinical Trial Update: Efficacy Study of Azithromycin-based Therapy for Bronchiolitis Obliterans [NA]
A clinical trial evaluating azithromycin-based therapy for bronchiolitis obliterans and graft-versus-host disease was terminated.
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CLINICAL_TRIALS trial_result · 2014-07-04Clinical Trial Update: Visilizumab for the Prevention of Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation [Phase 2]
A Phase 2 trial evaluating visilizumab to prevent graft-versus-host disease after allogeneic hematopoietic cell transplantation was terminat…
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CLINICAL_TRIALS research · 2014-07-01Clinical Trial Update: Tacrolimus and Mycophenolate Mofetil as Post-Grafting Immunosuppression [Phase 3]
A Phase 3 clinical trial update evaluating tacrolimus and mycophenolate mofetil as post-grafting immunosuppression for graft-versus-host dis…