Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-11-25Clinical Trial Update: IPL and Meibomian Gland Expression to Treat Ocular Rosacea Ocular GVHD [NA]
Completed Mayo Clinic trial evaluated intense pulsed light and Meibomian gland expression for treating ocular rosacea and ocular GVHD, with …
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CLINICAL_TRIALS trial_result · 2015-11-04Clinical Trial Update: Effectiveness of Topical Thalidomide to Treat Chronic Graft-Versus-Host-Disease Related Stomatitis [Phase 2]
Phase 2 trial evaluating topical thalidomide for chronic graft-versus-host-disease–related stomatitis; the study was terminated and results …
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FDA approval · 2015-10-06FDA Approved: JAKAFI — Supplemental Application (Incyte Corporation)
The FDA approved a supplemental application for Jakafi (ruxolitinib) submitted by Incyte Corporation, resulting in labeling updates.
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CLINICAL_TRIALS trial_result · 2015-09-24Clinical Trial Update: Treatment of Ocular Graft-versus-Host Disease (GVHD) With Topical Loteprednol Etabonate 0.5% [NA]
This completed trial assessed topical loteprednol etabonate 0.5% for ocular graft-versus-host disease presenting with dry eyes; results were…
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CLINICAL_TRIALS trial_result · 2015-09-10Clinical Trial Update: Tacrolimus, Sirolimus and Ustekinumab vs. Tacrolimus and Sirolimus for the Prevention of Acute Graft-Versus-Host Disease [Phase 2]
Phase 2 trial comparing tacrolimus and sirolimus with or without ustekinumab for prevention of acute graft-versus-host disease has completed…
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CLINICAL_TRIALS trial_result · 2015-07-24Clinical Trial Update: The Effect of Folinic Acid Rescue Following MTX GVHD Prophylaxis on Regimen Related Toxicity and Transplantation Outcome [Phase 2, Phase 3]
Phase 2/3 clinical trial update investigating folinic acid rescue after methotrexate-based GVHD prophylaxis to reduce regimen-related toxici…
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CLINICAL_TRIALS trial_result · 2015-07-20Clinical Trial Update: Graft-Versus-Host Disease in Treating Patients With Recurrent or Refractory Lymphoma or Hodgkin's Disease [Phase 3]
A Phase 3 trial investigating treatment for graft-versus-host disease in patients with recurrent or refractory lymphoma or Hodgkin's disease…
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CLINICAL_TRIALS trial_result · 2015-06-23Clinical Trial Update: Extended Use of Cannabidiol for the Prevention of Graft-versus-host-disease [Phase 2]
This is an update on a Phase 2 clinical trial evaluating extended use of cannabidiol to prevent graft-versus-host disease.
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CLINICAL_TRIALS research · 2015-06-19Clinical Trial Update: Cannabidiol for Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Stem Cell Transplantation [Phase 1, Phase 2]
A clinical trial is evaluating cannabidiol to prevent graft-versus-host disease in patients receiving allogeneic stem cell transplants, span…
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CLINICAL_TRIALS research · 2015-06-11Clinical Trial Update: Safety Study of Preimplantation Factor (PIF-1) to Treat Acute Steroid-Resistant Graft-Versus-Host Disease (GVHD) [Phase 1]
Phase 1 safety study evaluating Preimplantation Factor (PIF-1) for treatment of acute steroid-resistant graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Open-Label Study Designed to Evaluate the Safety and Preliminary Efficacy of ApoCell for the Prevention of Acute GvHD [Phase 1, Phase 2]
An open-label Phase 1/2 study is evaluating ApoCell for the prevention of acute graft-versus-host disease. The update notes safety and preli…
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CLINICAL_TRIALS trial_result · 2015-06-10Clinical Trial Update: Infliximab for the Prevention of Graft-versus-Host Disease Following Allogenic Hematopoietic Stem Cell Transplantation [Phase 2]
A Phase 2 clinical trial update reports completion of a study evaluating infliximab for preventing graft-versus-host disease after allogenei…
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CLINICAL_TRIALS research · 2015-06-09Clinical Trial Update: Mesenchymal Stromal Cells for Acute Graft Versus Host Disease [Phase 2]
Phase 2 clinical trial evaluating mesenchymal stromal cells for acute graft-versus-host disease. The current trial status is unknown.
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CLINICAL_TRIALS research · 2015-04-22Clinical Trial Update: Clinical Implications of HMGB1 in Patients Treated With Chemotherapy or Hematopoietic Stem Cell Transplantation
Clinical trial update exploring the clinical implications of HMGB1 in patients treated with chemotherapy or hematopoietic stem cell transpla…
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Alefacept for Chronic Graft Versus Host Disease [Phase 1, Phase 2]
Clinical trial update reporting the completion of Phase 1 and Phase 2 studies of alefacept for resistant chronic graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: A Study to Evaluate the Effect of ATG-F on Engraftment, Graft Versus Host Disease (GVHD) and Graft Versus Leukemia (GVL) Effect in Haplo-identical SCT [Phase 3]
Phase 3 study evaluating ATG-F for engraftment, graft-versus-host disease, and graft-versus-leukemia effects in haplo-identical stem cell tr…
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Alefacept for Prevention of Graft Versus Host Disease (GVHD) [Phase 3]
Phase 3 clinical trial evaluating alefacept to prevent graft-versus-host disease was terminated.
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Intra Arterial (IA) Steroids Infusion for Hepatic Acute Hepatic Graft Versus Host Disease (aGVHD) [NA]
A clinical trial evaluating intra-arterial steroid infusion for hepatic acute graft-versus-host disease has been terminated.
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CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell Transplantation [Phase 3]
Phase 3 randomized trial comparing sirolimus plus tacrolimus versus cyclosporine plus methotrexate for graft-versus-host disease prophylaxis…
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CLINICAL_TRIALS trial_result · 2015-04-08Clinical Trial Update: Tear Cytokine Analysis as a Prediction or Diagnostic Marker in Ocular GvHD
The trial evaluated tear cytokines as a potential predictor or diagnostic marker for ocular graft-versus-host disease, and the study has com…
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: Myfortic - Treatment for Extensive cGvHD [Phase 3]
Phase 3 trial of Myfortic for extensive chronic graft-versus-host disease has been terminated.
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CLINICAL_TRIALS trial_result · 2015-03-31Clinical Trial Update: Impact of Adnexal Involvement of the Severity and Prognosis of Chronic Graft-versus-Host Disease
Trial update examining whether adnexal involvement affects the severity and prognosis of chronic graft-versus-host disease (cGVHD) based on …
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Recombinant Human Keratinocyte Growth Factor in Unrelated and Related Transplants [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating recombinant human keratinocyte growth factor in unrelated and related transplants for graft-versus-host …
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Keratinocyte Growth Factor to Prevent Acute GVHD [Phase 1, Phase 2]
A Phase 1/2 trial evaluated keratinocyte growth factor (palifermin) for prevention of acute graft-versus-host disease and has completed.
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CLINICAL_TRIALS research · 2015-03-19Clinical Trial Update: Cannabidiol for the Treatment of Severe (Grades III/IV) Acute Graft-versus-host Disease [Phase 2]
A Phase 2 clinical trial update investigates cannabidiol as a treatment for severe acute graft-versus-host disease.