Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2016-06-15Clinical Trial Update: Maraviroc-Based GVHD Prophylaxis in HLA-Unrelated and HLA-Mismatched Related Transplantation [Phase 2]
Phase 2 clinical trial evaluating maraviroc-based prophylaxis to prevent graft-versus-host disease after hematopoietic stem cell transplanta…
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CLINICAL_TRIALS trial_result · 2016-05-27Clinical Trial Update: Acute Graft-versus-Host Disease Treatment (BMT CTN 0802) [Phase 3]
Phase 3 clinical trial update for Acute Graft-versus-Host Disease treatment (BMT CTN 0802) completed with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Mesenchymal Stem Cells as First Treatment Line for Resistant Acute Graft Versus Host Disease [Phase 2]
This document reports a Phase 2 clinical trial evaluating mesenchymal stem cells as the first-line therapy for resistant acute graft-versus-…
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CLINICAL_TRIALS withdrawal · 2016-05-06Clinical Trial Update: Tocilizumab for Chronic Graft-versus-Host Disease Treatment [Phase 2]
A Phase 2 clinical trial of tocilizumab for chronic graft-versus-host disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Phase II Trial of Pentostatin in Steroid Refractory Acute Graft Versus Host Disease [Phase 2]
Phase II trial evaluating pentostatin for steroid-refractory acute graft-versus-host disease has completed.
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CLINICAL_TRIALS withdrawal · 2016-04-25Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Neihulizumab vs "Conventional Treatment" to Treat Sr-aGvHD [Phase 2]
A Phase 2 trial evaluating neihulizumab for steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic cell transplan…
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CLINICAL_TRIALS trial_result · 2016-04-22Clinical Trial Update: Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation [Phase 1, Phase 2]
Clinical trial update on memory T-cell infusion after TCR-alpha/beta depleted hematopoietic stem cell transplantation, with Phase 1/2 status…
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: T-Cell Depletion in Unrelated Donor Marrow Transplantation [Phase 3]
Phase 3 trial evaluating T-cell depletion in unrelated donor bone marrow transplantation has completed, studying its impact on graft-versus-…
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CLINICAL_TRIALS trial_result · 2016-04-08Clinical Trial Update: Safety and Efficacy of UC-MSC in Patients With Acute Severe Graft-versus-host Disease [Phase 1, Phase 2]
This Phase 1/2 clinical trial evaluates the safety and efficacy of UC-MSC therapy for acute graft-versus-host disease. It is sponsored by th…
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FDA approval · 2016-03-21FDA Approved: IMBRUVICA — Supplemental Application (Pharmacyclics LLC)
FDA approved a supplemental application for IMBRUVICA (ibrutinib) filed by Pharmacyclics LLC. The document indicates FDA action on a supplem…
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CLINICAL_TRIALS trial_result · 2016-03-01Clinical Trial Update: Study to Assess the Safety and Efficacy of Tacrolimus (Prograf Capsule/Injection) and Methotrexate (MTX) Combination Therapy for Prevention of Graft Versus Host Disease (GVHD) in Patients Who Received Peripheral Hematopoietic Stem Cell Transplantation From a Sibling Donor [Phase 4]
Phase 4 study evaluating safety and efficacy of tacrolimus (Prograf) with methotrexate for prevention of graft-versus-host disease in patien…
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Prevention of Ocular Graft-Versus-Host Disease With Topical Cyclosporine in Recipients of Allogeneic HSCT [Phase 2]
A Phase 2 trial evaluating topical cyclosporine to prevent ocular graft-versus-host disease in recipients of allogeneic hematopoietic stem c…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: CC-4047 (Pomalidomide) for Graft vs. Host Disease [Phase 2]
Phase 2 trial of pomalidomide (CC-4047) for graft-versus-host disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Theralux Extracorporeal Photochemotherapy (ECP) in Patients With Extensive Chronic Graft Versus Host Disease (GvHD) [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial of Theralux Extracorporeal Photochemotherapy (ECP) for extensive chronic graft-versus-host disease has comp…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Rituximab for the Primary Treatment of Denovo Extensive Chronic Graft Versus Host Disease (GVHD) [Phase 2]
This document summarizes a Phase 2 trial evaluating rituximab as the primary treatment for extensive chronic graft-versus-host disease (GVHD…
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CLINICAL_TRIALS trial_result · 2016-02-19Clinical Trial Update: Multi Donor Mismatched Stem Cell Transplantation (MDT) [Phase 1, Phase 2]
Clinical trial update on a Phase 1/2 study of multi-donor mismatched stem cell transplantation for graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Blood and Marrow Transplant Clinical Research Network [NA]
The Blood and Marrow Transplant Clinical Research Network study has completed, summarizing transplantation approaches across hematologic dis…
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: 70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014 [NA]
This clinical trial evaluated using 70% ethanol to decontaminate central venous lines exposed to calcineurin inhibitors in patients undergoi…
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CLINICAL_TRIALS trial_result · 2016-01-21Clinical Trial Update: Efficacy and Safety Study of Budesonide to Treat Oral Chronic Graft vs Host Disease (cGvHD) [Phase 3]
A Phase 3 trial evaluating budesonide for efficacy and safety in oral chronic graft-versus-host disease has completed.
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CLINICAL_TRIALS research · 2016-01-18Clinical Trial Update: Bortezomib for the Treatment of Refractory Chronic Graft-vs-Host Disease(cGVHD) [Phase 2]
A Phase 2 clinical trial is evaluating bortezomib for refractory chronic graft-versus-host disease, sponsored by Baylor Research Institute. …
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CLINICAL_TRIALS trial_result · 2016-01-11Clinical Trial Update: Comparison of Two Automated Mononuclear Collection Systems in Patients Undergoing Extracorporeal Photochemotherapy. A Cross-over Equivalence Study. (MNC_CMNC) [Phase 3]
A Phase 3 cross-over trial comparing two automated mononuclear cell collection systems used during extracorporeal photochemotherapy in patie…
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CLINICAL_TRIALS trial_result · 2015-12-23Clinical Trial Update: Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye [Phase 2]
Phase 2 trial comparing thymosin beta-4 eye drops to vehicle for severe dry eye, including Sjögren's syndrome; results were posted in 2015 a…
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CLINICAL_TRIALS trial_result · 2015-12-21Clinical Trial Update: Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney Cancer [Phase 2]
Phase 2 trial assessing low-intensity stem cell transplantation with multiple lymphocyte infusions for advanced kidney cancer (renal cell ca…
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CLINICAL_TRIALS trial_result · 2015-12-16Clinical Trial Update: Photochemotherapy and Graft-versus-leukemia in Acute-leukemia
This clinical trial update reports a completed study from Karolinska University Hospital evaluating photochemotherapy to enhance graft-versu…
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CLINICAL_TRIALS research · 2015-12-02Clinical Trial Update: Carfilzomib for the Prevention of Graft Versus Host Disease [Phase 1]
Phase 1 clinical trial update evaluating carfilzomib for prevention of graft-versus-host disease; current status is unknown.