Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: In Vivo Treg Expansion and Graft-Versus-Host Disease Prophylaxis [Phase 2]
A Phase 2 trial of in vivo regulatory T cell expansion for prophylaxis of graft-versus-host disease has completed, with results posted in Ju…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Cyclosporine Implant for Ocular Graft-Versus-Host Disease [Phase 1]
A Phase 1 trial evaluating a cyclosporine implant for ocular graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Extracorporeal Photopheresis to Treat Chronic Graft-Versus-Host Disease [Phase 2]
This clinical trial update reports completion of a Phase 2 study evaluating extracorporeal photopheresis for chronic graft-versus-host disea…
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CLINICAL_TRIALS trial_result · 2017-06-19Clinical Trial Update: A Optimal Anti-Thymoglobuline (ATG) Dose Decrease cGVHD But Not Increase Leukemia Relapse for Haplo-HSCT [Phase 4]
A Phase 4 trial suggests that reducing the dose of anti-thymoglobulin (ATG) lowers chronic graft-versus-host disease without raising leukemi…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Atorvastatin for the Prophylaxis of Acute GVHD in Patients Undergoing Matched Sibling Allogeneic Transplantation [Phase 2]
Phase 2 trial evaluating atorvastatin to prevent acute graft-versus-host disease after matched-sibling allogeneic transplantation; results w…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Safety and Efficacy Study of T-Guard to Treat Steroid-resistant Acute GVHD [Phase 1, Phase 2]
Completed Phase 1/2 study evaluating safety and efficacy of T-Guard for steroid-resistant acute graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Sirolimus & Mycophenolate Mofetil as GvHD Prophylaxis in Myeloablative, Matched Related Donor HCT [Phase 2]
Phase 2 trial of sirolimus and mycophenolate mofetil as graft-versus-host disease prophylaxis in myeloablative, matched related donor hemato…
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: Donor Peripheral Stem Cell Transplant and Donor Natural Killer Cell Transplant After Total-Body Irradiation, Thiotepa, Fludarabine, and Muromonab-CD3 in Treating Patients With Leukemia or Other Blood Diseases [Phase 2]
Phase 2 trial evaluating donor peripheral stem cell transplant and donor natural killer cell transplant after conditioning with total-body i…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Sirolimus as Secondary Therapy in Chronic Graft-Versus-Host Disease Not Responding To Prior Treatment [Phase 2]
Phase 2 trial evaluating sirolimus as a secondary therapy for chronic graft-versus-host disease not responding to prior treatment; the study…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: The Effect of Human Leukocyte Antigen Macthing on Guiding Tacrolimus Regimen After Liver Transplantation [NA]
Clinical trial assessing whether HLA matching can guide tacrolimus dosing after liver transplantation. The study also considers outcomes rel…
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Transdermal Patch to Monitor Inflammatory Biomarkers of GVHD [NA]
A study evaluating a transdermal patch for monitoring inflammatory biomarkers in Graft Versus Host Disease has completed, with results poste…
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating pentostatin and lymphocyte infusion to prevent graft rejection after donor stem cell transplantation—compl…
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Sirolimus as Treatment of Steroid-Refractory or Steroid-Dependent Chronic Graft-Versus-Host Disease [Phase 2]
A Phase 2 study evaluated sirolimus for treating chronic graft-versus-host disease that is either steroid-refractory or steroid-dependent; t…
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Clinical and Biomarker Study of the Efficacy of Extracorporeal Photopheresis in Graft-versus-host Disease
Clinical trial update noting the completion of a study evaluating extracorporeal photopheresis for graft-versus-host disease and related bio…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant [Phase 1]
A Phase 1 trial evaluating rasburicase to prevent graft-versus-host disease in patients undergoing donor stem cell transplantation; the stud…
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Efalizumab in Treating Patients With Graft-Versus-Host Disease of the Skin That Did Not Respond to Previous Steroids [NA]
A terminated clinical trial evaluated Efalizumab for graft-versus-host disease of the skin that did not respond to steroids, with results po…
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Romidepsin in Treating Patients With Steroid-Refractory Graft-versus-Host Disease [NA]
Romidepsin was evaluated in patients with steroid-refractory graft-versus-host disease; the trial was terminated and results were posted in …
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: A Study of AbGn-168H in Patients With Steroid Refractory Acute Graft-vs-Host Disease After Donor Stem Cell Transplant [Phase 1]
Phase 1 study evaluating AbGn-168H for steroid-refractory acute graft-versus-host disease after donor stem cell transplant has been terminat…
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CLINICAL_TRIALS trial_result · 2017-03-22Clinical Trial Update: Tacrolimus/Methotrexate Versus Cyclosporine/Methotrexate for Prophylaxis of Graft Versus Host Disease [Phase 2, Phase 3]
Phase 2/3 trial comparing tacrolimus/methotrexate versus cyclosporine/methotrexate for prophylaxis of graft-versus-host disease has complete…
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: Extracorporeal Photopheresis Using Theraflex ECP™ for Patients With Refractory Chronic Graft Versus Host Disease (cGVHD) [Phase 2]
This document provides a Phase 2 clinical trial update evaluating Extracorporeal Photopheresis using Theraflex ECP for patients with refract…
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CLINICAL_TRIALS trial_result · 2017-03-16Clinical Trial Update: Cyclophosphamide and Anti-thymocyte Globulin Followed By Methotrexate and Cyclosporine in Preventing Chronic Graft-Versus-Host Disease in Patients With Severe Aplastic Anemia Undergoing Donor Bone Marrow Transplant [Phase 2]
Phase 2 study evaluating a conditioning regimen of cyclophosphamide and anti-thymocyte globulin followed by methotrexate and cyclosporine to…
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CLINICAL_TRIALS trial_result · 2017-03-15Clinical Trial Update: Pentostatin in Treating Patients With Refractory Chronic Graft-Versus-Host Disease [Phase 2]
Phase 2 trial evaluating pentostatin for refractory chronic graft-versus-host disease has completed with results posted.
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CLINICAL_TRIALS research · 2017-02-27Clinical Trial Update: Blood Based Eyedrops From Different Sources in the Treatment of Severe Keratopathy [NA]
A clinical trial is evaluating blood-based eyedrops from different sources for severe keratopathy, including keratopathy associated with Sjo…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: PhaseII,Open-label,Pilot Study Evaluating the Safety+Efficacy of Certican ® in the Prevention of Chronic Graft-versus-host Disease+Late Pulmonary Complications After Allogeneic Hematopoietic Cell Transplantation Blood [Phase 2]
Phase II open-label pilot trial evaluating everolimus (Certican) for the prevention of chronic graft-versus-host disease and late pulmonary …
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Anti Cytokine Combination Therapy With Daclizumab and Infliximab for Treatment of Steroid Refractory Acute GVHD [Phase 4]
This document reports the completion of a Phase 4 clinical trial evaluating a combination therapy of daclizumab and infliximab for steroid-r…