Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-05-09Clinical Trial Update: Clinical Study to Investigate the Biological Activity, Safety, Tolerability, and Pharmacokinetics of Ponesimod in Subjects With Symptomatic Chronic GVHD [Phase 2]
Phase 2 study evaluating the biological activity, safety, tolerability, and pharmacokinetics of ponesimod in symptomatic chronic graft-versu…
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CLINICAL_TRIALS trial_result · 2018-04-24Clinical Trial Update: ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis [Phase 4]
Phase 4 clinical trial update on using antithymocyte globulin for prophylaxis of acute graft-versus-host disease in haploidentical hematopoi…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: Busulfan, Cyclophosphamide, & Antithymocyte Globulin Followed by Stem Cell Transplant in Treating Hematologic Cancer [Phase 2]
Phase 2 clinical trial evaluating busulfan, cyclophosphamide, and antithymocyte globulin followed by stem cell transplant for hematologic ca…
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Phase I Trial of LDE225 for Steroid-refractory Chronic GVHD After Allogeneic HSCT [Phase 1]
Phase I trial of LDE225 (sonidegib) for steroid-refractory chronic graft-versus-host disease after allogeneic hematopoietic stem cell transp…
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CLINICAL_TRIALS trial_result · 2018-03-06Clinical Trial Update: A Phase 1/2 Trial of Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-Host-Disease [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating donor regulatory T-cells for treatment of chronic graft-versus-host disease refractory to steroids.
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: Pomalidomide for Chronic Graft-versus-Host Disease [Phase 2]
A Phase 2 clinical trial of pomalidomide for chronic graft-versus-host disease has completed and posted results.
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CLINICAL_TRIALS trial_result · 2018-01-05Clinical Trial Update: A Pilot Study of Alpha-1-Antitrypsin (AAT) in Steroid Refractory Acute Graft vs Host Disease [Phase 2]
Phase 2 pilot study of alpha-1-antitrypsin for steroid-refractory acute graft-versus-host disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-01-02Clinical Trial Update: Vorinostat Plus Tacrolimus & Methotrexate to Prevent Graft vs Host Disease Following Unrelated Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating vorinostat with tacrolimus and methotrexate to prevent graft-versus-host disease after unrelated stem cell transpla…
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases [Phase 1]
Phase 1 trial evaluating the safety of Umbilical Cord Blood T-Regulatory Cell infusion followed by donor cord blood transplant in patients w…
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CLINICAL_TRIALS withdrawal · 2017-12-02Clinical Trial Update: Treg Cells for AGVHD in Non-myeloablative UCB Transplant [Phase 2]
A Phase 2 clinical trial investigating regulatory T cells to prevent acute graft-versus-host disease in non-myeloablative umbilical cord blo…
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: A Phase 2 Trial of Rituximab and Corticosteroid Therapy for Newly Diagnosed Chronic Graft Versus Host Disease [NA]
Phase 2 trial evaluating rituximab plus corticosteroid therapy as initial treatment for newly diagnosed chronic graft-versus-host disease; r…
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CLINICAL_TRIALS research · 2017-11-13Clinical Trial Update: Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases [NA]
This clinical-trial update reviews the mechanisms by which phototherapy and photochemotherapy exert therapeutic effects in skin diseases. It…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Skin Disease and Pulmonary Mortality After Transplantation
A completed clinical trial update reporting on skin disease and pulmonary mortality after transplantation, focusing on acute graft-versus-ho…
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CLINICAL_TRIALS withdrawal · 2017-10-11Clinical Trial Update: MicroRNAs as Diagnostic and Predictive Biomarkers for Acute Graft Versus Host Disease
The clinical trial evaluating microRNAs as diagnostic and predictive biomarkers for acute graft-versus-host disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-10-06Clinical Trial Update: A Phase 2A Study of ALXN1007 in Participants With Newly Diagnosed Acute Lower Gastrointestinal Graft-Versus-Host Disease [Phase 2]
Phase 2A study of ALXN1007 for newly diagnosed acute lower gastrointestinal graft-versus-host disease (GVHD) was terminated; results posted …
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CLINICAL_TRIALS trial_result · 2017-09-05Clinical Trial Update: Phase II Study of Tocilizumab for Patients With Glucocorticoid-refractory Acute GVHD After Allogeneic Hematopoetic Stem Cell Transplant (HSCT) [Phase 2]
Phase II study of Tocilizumab for glucocorticoid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transpl…
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CLINICAL_TRIALS withdrawal · 2017-08-28Clinical Trial Update: Safety and Efficacy of Autologous PRP and PPP Eye Drops in the Treatment of Ocular GVHD [Phase 1]
A Phase 1 trial evaluating autologous PRP and PPP eye drops for ocular graft-versus-host disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: Donor Atorvastatin Treatment for Preventing Severe Acute Graft-Versus-Host Disease in Patients Undergoing Myeloablative Peripheral Blood Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating donor atorvastatin to prevent severe acute graft-versus-host disease in patients undergoing myeloablative periphera…
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CLINICAL_TRIALS trial_result · 2017-08-16Clinical Trial Update: Safety and Efficacy Study of Photopheresis Plus Standard Therapy to Treat Chronic Graft-versus-Host Disease [Phase 2]
Phase 2 trial assessing safety and efficacy of photopheresis plus standard therapy for chronic graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2017-08-16Clinical Trial Update: Safety and Efficacy Study of Photopheresis With UVADEX to Prevent Graft-versus-Host Disease [Phase 2]
Phase 2 study evaluating photopheresis with UVADEX to prevent graft-versus-host disease after transplantation has completed.
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CLINICAL_TRIALS trial_result · 2017-08-16Clinical Trial Update: Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Acute Graft Versus-Host Disease [Phase 3]
A Phase 3 trial evaluating extracorporeal photoimmune therapy with UVADEX (amotosalen) for acute graft-versus-host disease was terminated.
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CLINICAL_TRIALS research · 2017-07-21Clinical Trial Update: Analysis of Transcriptomic Profile of Graft-versus-host Disease (GHVD) After Allogeneic Grafting of Hematopoietic Stem Cells
This clinical trial update analyzes the transcriptomic profile of graft-versus-host disease after allogeneic hematopoietic stem cell transpl…
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CLINICAL_TRIALS research · 2017-07-19Clinical Trial Update: Changes in the Gut Microbiota of Patients Undergoing Allogeneic Stem Cell Transplantation (COLLECT)
This clinical trial update describes observed changes in the gut microbiota of patients undergoing allogeneic hematopoietic stem cell transp…
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CLINICAL_TRIALS trial_result · 2017-07-18Clinical Trial Update: Standard of Care vs. Bortezomib in Graft-Versus Host Disease After Hematopoietic Stem Cell Transplant [Phase 2]
Phase 2 trial comparing standard of care versus bortezomib for graft-versus-host disease after hematopoietic stem cell transplantation; the …
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: Bandage Lenses in Treating Patients With Ocular Graft-Versus-Host Disease [Phase 2]
A Phase 2 clinical trial evaluated bandage contact lenses for treating ocular complications in graft-versus-host disease, with results poste…