Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2019-02-19Clinical Trial Update: Toward Immune Biomarkers for Tolerance and GvHD in Humans
This clinical trial update describes ongoing research on immune biomarkers aimed at tolerance and preventing graft-versus-host disease in hu…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Minor Salivary Gland Transplantation for Cicatrizing Conjunctivitis [NA]
This clinical trial update describes a study of minor salivary gland transplantation for cicatricial conjunctivitis, sponsored by National T…
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CLINICAL_TRIALS research · 2019-02-12Clinical Trial Update: Donor Lymphocyte Infusion After Stem Cell Transplant in Treating Patients With Haematological Cancers [Phase 2]
This clinical trial update describes a Phase 2 study evaluating donor lymphocyte infusion after stem cell transplant for hematologic cancers…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Carfilzomib in Treating Patients With Chronic Graft-Versus-Host Disease [Phase 2]
A Phase 2 clinical trial evaluating carfilzomib for chronic graft-versus-host disease has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Ixazomib Citrate in Treating Patients With Chronic Graft-versus-Host Disease [Phase 2]
A Phase 2 clinical trial evaluated ixazomib citrate for chronic graft-versus-host disease; the study has completed and results were posted i…
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CLINICAL_TRIALS trial_result · 2019-01-25Clinical Trial Update: Comparison of Gut Microbiota, Inflammation and Symptoms Following Allogeneic HSCT
Completed clinical trial investigating gut microbiota, inflammation, and symptoms following allogeneic hematopoietic stem cell transplantati…
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CLINICAL_TRIALS other · 2019-01-18Clinical Trial Update: Umbilical Cord Derived Mesenchymal Stromal Cells For The Treatment of Severe Steroid-resistant Graft Versus Host Disease [Phase 1, Phase 2]
This clinical trial update outlines a Phase 1/Phase 2 study evaluating the use of umbilical cord-derived mesenchymal stromal cells to treat …
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CLINICAL_TRIALS trial_result · 2019-01-08Clinical Trial Update: Safety of Post-transplant Alpha-beta Depleted T-cell Infusion Following Haploidentical Stem Cell Transplant (Haplo SCT) [NA]
Clinical trial update on the safety of post-transplant alpha-beta depleted T-cell infusion after haploidentical stem cell transplantation; r…
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CLINICAL_TRIALS trial_result · 2018-12-26Clinical Trial Update: Efficacy and Tolerability of Entospletinib in Combination With Systemic Corticosteroids as First-Line Therapy in Adults With Chronic Graft Versus Host Disease (cGVHD) [Phase 2]
Phase 2 trial investigating entospletinib with systemic corticosteroids as first-line therapy for chronic graft-versus-host disease; study t…
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CLINICAL_TRIALS trial_result · 2018-11-23Clinical Trial Update: Low-Dose Total Lymphoid Irradiation in Treating Patients With Refractory Chronic Graft-versus-Host Disease After Donor Stem Cell Transplant [NA]
Clinical trial update on low-dose total lymphoid irradiation for refractory chronic graft-versus-host disease after donor stem cell transpla…
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CLINICAL_TRIALS trial_result · 2018-11-16Clinical Trial Update: Lactobacillus Rhamnosus GG in Reducing Incidence of Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant [NA]
Clinical trial assessing Lactobacillus rhamnosus GG to reduce graft-versus-host disease in patients after donor stem cell transplantation ha…
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CLINICAL_TRIALS trial_result · 2018-10-30Clinical Trial Update: Alpha 1 Anti-Trypsin (AAT) in Treating Patients With Acute Graft-Versus-Host Disease GVHD) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating Alpha 1 Antitrypsin (AAT) for acute graft-versus-host disease (GVHD) after transplantation; study comple…
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CLINICAL_TRIALS trial_result · 2018-10-18Clinical Trial Update: A Phase II Trial of Low-Dose Interleukin-2 (IL-2) Added to Extra-Corporeal Photopheresis for Steroid-Refractory cGVHD [Phase 2]
Phase II study evaluating the addition of low-dose interleukin-2 to extracorporeal photopheresis for steroid-refractory chronic graft-versus…
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CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythematosus (SLE) [Phase 1, Phase 2]
Clinical trial update for nonmyeloablative conditioning and transplantation in refractory systemic lupus erythematosus (SLE) has terminated;…
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CLINICAL_TRIALS trial_result · 2018-09-26Clinical Trial Update: The Role of Cyclosporine in Blood Cell Transplants With T-Cell Add-Back for Blood Cancers [Phase 2]
Phase 2 trial evaluating cyclosporine with T-cell add-back in blood cell transplant settings for hematologic cancers, including chronic lymp…
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CLINICAL_TRIALS trial_result · 2018-09-14Clinical Trial Update: High-Dose Cyclophosphamide for Steroid Refractory GVHD [Phase 2]
Phase 2 trial investigating high-dose cyclophosphamide for steroid-refractory graft-versus-host disease has completed with results posted in…
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CLINICAL_TRIALS trial_result · 2018-08-14Clinical Trial Update: Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801) [Phase 2, Phase 3]
Phase 2/3 trial update for chronic graft-versus-host disease treatment completed with results posted in 2018.
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CLINICAL_TRIALS research · 2018-07-30Clinical Trial Update: Expansion of Invariant NKT Cells for a Cell Immunotherapeutic Approach Allowing the Control of Graft Versus Host-disease and Preserving the Graft Versus Leukemia Effect After Allogeneic Hematopoietic Stem Cell Transplantation
This clinical trial update describes expanding invariant natural killer T (iNKT) cells as a cell therapy to control graft-versus-host diseas…
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: A Study Comparing Corticosteroids Alone Versus Corticosteroids and Extracorporal Photopheresis (ECP) as First-line Treatment of Standard II Acute Graft-versus-host Disease [Phase 2]
A Phase 2 study comparing corticosteroids alone versus corticosteroids with extracorporeal photopheresis as first-line treatment for standar…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Brentuximab Vedotin for Steroid Refractory GvHD [Phase 1]
A Phase 1 study evaluating brentuximab vedotin for steroid-refractory graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Phase I Trial of Brentuximab Vedotin for Refractory Chronic Graft-vs.-Host Disease (GVHD) [Phase 1]
Phase I trial of brentuximab vedotin for refractory chronic graft-versus-host disease has been terminated; the study was conducted at Massac…
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: An Open Label Phase II Trial of Topical Sirolimus for the Treatment of Refractory Oral Chronic Graft-versus-Host-Disease [Phase 2]
Open-label Phase II study evaluating topical sirolimus for refractory oral chronic graft-versus-host disease; the trial has been terminated …
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Donor Th2 Cells to Prevent Graft-Versus-Host Disease in Bone Marrow Transplants [Phase 1]
Phase 1 clinical trial evaluating donor T-helper 2 (Th2) cell therapy to prevent graft-versus-host disease after bone marrow transplantation…
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CLINICAL_TRIALS research · 2018-06-14Clinical Trial Update: Cognitive Function and Patient-Reported Quality of Life Outcomes Investigation in Patients Taking Vorinostat
Completed clinical trial assessing cognitive function and patient-reported quality of life in patients taking vorinostat, with outcomes rela…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Photopheresis for the Treatment of Acute Graft Versus Host Disease [Phase 2]
Phase 2 trial update evaluating extracorporeal photopheresis for acute graft-versus-host disease; completed with results posted.