Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: A Study to Assess the Safety and Pharmacokinetics of GDC-8264 in Combination With Standard of Care in Participants With Acute Graft-Versus-Host Disease (aGVHD) [Phase 1]
This Phase 1 study evaluates the safety and pharmacokinetics of GDC-8264 in combination with standard of care in participants with acute gra…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: A Trial to Evaluate the Safety and Efficacy of NCR102 in Subjects With aGVHD [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating NCR102 for safety and efficacy in subjects with acute graft-versus-host disease; the study status is N…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: The Safety and Efficacy of Fecal Microbiota Transplant (FMT) for Steroid-refractory Graft-versus-host Disease [NA]
Completed clinical trial update evaluating the safety and efficacy of fecal microbiota transplant for steroid-refractory graft-versus-host d…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD [Phase 1, Phase 2]
This clinical trial update reports a completed Phase 1/2 study evaluating EQ001 in patients with acute graft-versus-host disease, including …
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: Activity, Safety and Pharmacokinetics in Pediatric Subjects With Moderate and Severe Chronic Graft vs. Host Disease After Allogeneic Stem Cell Transplant [Phase 2]
Phase 2 study evaluating activity, safety, and pharmacokinetics of a therapy in pediatric patients with moderate to severe chronic graft-ver…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT) [Phase 1]
Phase 1 clinical trial assessing a preventive therapy to reduce graft-versus-host disease in participants with hematologic malignancies unde…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Efficacy of Human Chorionic Gonadotropin in Acute GVHD Treatment [Phase 2]
Phase 2 clinical trial evaluating the efficacy of human chorionic gonadotropin for treating acute graft-versus-host disease.
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: The Skin Microbiome in Graft Versus Host Disease
A ClinicalTrials.gov update indicates an active, not recruiting study sponsored by University Hospital Basel examining the skin microbiome i…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Extracorporal Photopheresis With UVADEX Plus Standard Steroid Treatment for High Risk Acute Graft-versus-host Disease [Phase 2]
This clinical trial update describes a Phase 2 study evaluating extracorporeal photopheresis with UVADEX plus standard steroids for high-ris…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Vaginal Microbiome and the Development of Vulvovaginal Graft Versus Host Disease
This clinical trial update describes a study on the vaginal microbiome and the development of vulvovaginal graft-versus-host disease in pati…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: FMT in Gut aGVHD Treated
A clinical trial is evaluating fecal microbiota transplantation for gut involvement in acute graft-versus-host disease and is currently recr…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Obinutuzumab in cGVHD After Allogeneic Peripheral Blood Stem Cell Transplantation [Phase 2]
A Phase 2 study evaluating obinutuzumab for chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplantation ha…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: The Application of Novel Identified CD8 Regulatory Precursors in Inducing Immune Tolerance After Allo-HSCT
The study investigates novel CD8 regulatory precursor therapy to induce immune tolerance after allogeneic hematopoietic stem cell transplant…
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis Implantation [NA]
This clinical trial update reports the safety and performance results of the ARGOS-IO System used during Boston Keratoprosthesis implantatio…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Comparing the Therapeutic Effects of Using Ruxolitinib and Steroids Concurrently to Steroids Alone as Initial Treatment In Patients Diagnosed With Chronic Graft-versus-host Disease at a Grade of Moderate or Higher Severity [Phase 2]
A Phase 2 trial assesses whether adding ruxolitinib to steroids as initial therapy improves outcomes in moderate-or-higher chronic graft-ver…
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Extracorporeal Photopheresis for Acute Graft Versus Host Disease [Phase 2, Phase 3]
A phase 2/phase 3 trial evaluating extracorporeal photopheresis for acute graft-versus-host disease has completed.
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host Disease [Phase 2]
A Phase 2 clinical trial of TQ05105 tablets for chronic graft-versus-host disease is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: IRENE-G Study: Impact of Resistance Exercise and Nutritional Endorsement on GvHD Symptoms [NA]
Clinical trial update for the IRENE-G study evaluating resistance exercise and nutritional endorsement on graft-versus-host disease symptoms…
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: Study on the Treatment With Water-filtered Infrared-A (wIRA) Radiation in Patients With Morphea and Sclerotic Graft-versus-host Disease [NA]
Clinical trial update indicates that a study evaluating water-filtered infrared-A (wIRA) radiation for Morphea and sclerotic graft-versus-ho…
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CLINICAL_TRIALS withdrawal · 2025-01-29Clinical Trial Update: Correlation of Serum Gasdermin-D and NLRP-3 Inflammasome Levels With GVHD Biomarkers and Endothelial Damage Markers in Graft-Versus-Host Disease
A clinical trial investigating correlations between serum biomarkers and GVHD-related endothelial damage has been withdrawn. The study recor…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Novel BET Inhibitor PLX51107 for Steroid-Refractory Acute GVHD [Phase 1, Phase 2]
Phase 1/2 trial of the BET inhibitor PLX51107 for steroid-refractory acute graft-versus-host disease was terminated; results have been poste…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Measurements of Resting Energy Expenditure in Patients With or at Risk of Developing Graft Versus Host Disease
This clinical trial update reports on measurements of resting energy expenditure in patients with or at risk of developing graft-versus-host…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease [Phase 2, Phase 3]
GRAVITAS-309 evaluated itacitinib with corticosteroids as initial therapy for chronic graft-versus-host disease; the Phase 2/3 trial was ter…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease [Phase 2]
A Phase 2 trial evaluating frontline ibrutinib without corticosteroids for newly diagnosed chronic graft-versus-host disease has completed. …
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Assessment of MicroRNA Expression in Acute Graft-versus-Host Disease
A completed clinical study update examining microRNA expression in acute graft-versus-host disease in patients receiving allogeneic stem cel…