Glioblastoma

CLINICAL_TRIALS research · 2024-11-05

Clinical Trial Update: TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and Meningiomas [Phase 1, Phase 2]

A Phase 1/2 clinical trial is evaluating the combination of tumor-infiltrating lymphocyte (TIL) therapy with pembrolizumab for advanced brai…

CLINICAL_TRIALS other · 2024-10-31

Clinical Trial Update: Clinical Study on the Safety and Efficacy of TS-2021 in the Treatment of Recurrent Malignant Glioma [Phase 1]

Phase 1 clinical trial is recruiting to evaluate safety and preliminary efficacy of TS-2021 for recurrent malignant glioma, including gliobl…

CLINICAL_TRIALS trial_result · 2024-10-31

Clinical Trial Update: Study to Evaluate the Safety and Efficacy of ASC40 Tablets in Combination With Bevacizumab in Subjects With rGBM [Phase 3]

Phase 3 study evaluating ASC40 tablets in combination with bevacizumab for recurrent glioblastoma; the trial is currently active but not rec…

CLINICAL_TRIALS research · 2024-10-31

Clinical Trial Update: A Study Using Radiation Therapy and Temozolomide to Treat Glioblastoma in Patients Over 70 [Phase 1, Phase 2]

This clinical trial update describes a Phase 1/2 study investigating the combination of radiation therapy and temozolomide for glioblastoma …

CLINICAL_TRIALS trial_result · 2024-10-30

Clinical Trial Update: Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma [Phase 1]

Phase 1 trial evaluates genetically modified T-cells (CAR-T) in patients with recurrent or refractory malignant glioma. Results have been po…

CLINICAL_TRIALS trial_result · 2024-10-29

Clinical Trial Update: Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma [Phase 1]

Amgen's Phase 1 study of AMG 596 in EGFRvIII-positive glioblastoma has been terminated, and results have been posted.

CLINICAL_TRIALS research · 2024-10-29

Clinical Trial Update: XS005 Injection Combined With Stupp Regimen for Adjuvant Chemotherapy in Subjects With Primary Glioblastoma(GBM) [Phase 1, Phase 2]

A Phase 1/Phase 2 trial evaluating XS005 injections with the Stupp regimen for adjuvant chemotherapy in patients with primary glioblastoma h…

CLINICAL_TRIALS research · 2024-10-24

Clinical Trial Update: Artificial Intelligence-Guided Radiotherapy Planning for Glioblastoma

This entry reports a clinical trial evaluating artificial intelligence-guided radiotherapy planning for glioblastoma. The study status is NO…

CLINICAL_TRIALS trial_result · 2024-10-22

Clinical Trial Update: Non-Contrast Perfusion Using Arterial Spin Labeled MR Imaging for Assessment of Therapy Response in Glioblastoma [NA]

A completed clinical trial evaluating non-contrast perfusion using arterial spin-labeled MR imaging to assess therapy response in glioblasto…

CLINICAL_TRIALS research · 2024-10-17

Clinical Trial Update: Lonafarnib and Temozolomide in Treating Patients with Glioblastoma Multiforme That is Recurrent or Did Not Respond to Previous Treatment with Temozolomide [Phase 1]

Phase 1 trial update evaluating lonafarnib in combination with temozolomide for recurrent glioblastoma multiforme and related gliomas.

CLINICAL_TRIALS trial_result · 2024-10-15

Clinical Trial Update: Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma [Phase 1]

Phase 1 trial evaluating selinexor in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma (and gliosarcoma)…

CLINICAL_TRIALS trial_result · 2024-10-15

Clinical Trial Update: Combined Treatment of Camrelizumab and Bevacizumab for Adult Patients with Recurrent Glioblastoma (GBM) [Phase 2]

A Phase 2 trial evaluating the combination of camrelizumab and bevacizumab in adults with recurrent glioblastoma has been terminated.

CLINICAL_TRIALS trial_result · 2024-10-10

Clinical Trial Update: Phase I Study of APX005M in Pediatric Central Nervous System Tumors [Phase 1]

Phase I study of APX005M in pediatric central nervous system tumors; the trial is active but not recruiting and results have been posted. Sp…

CLINICAL_TRIALS trial_result · 2024-10-09

Clinical Trial Update: F18 Fluciclovine PET/CT in Assessing Tumor Volume and Radiation Therapy Response in Patients With Glioblastoma Undergoing Surgery [NA]

A completed clinical trial evaluating F18 fluciclovine PET/CT to measure tumor volume and response to radiation therapy in glioblastoma pati…

CLINICAL_TRIALS research · 2024-10-02

Clinical Trial Update: Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies [Phase 1, Phase 2]

This clinical trial update describes ongoing Phase 1/2 evaluation of NGM707 as a monotherapy and in combination with pembrolizumab in advanc…

CLINICAL_TRIALS research · 2024-10-02

Clinical Trial Update: Extensive Resection of Malignant Brain Tumors Using Advanced Imaging Techniques [NA]

The study evaluates extensive surgical resection of malignant brain tumors using advanced imaging techniques and is currently recruiting.

CLINICAL_TRIALS other · 2024-10-01

Clinical Trial Update: TVI-Brain-1 in Expanded Access Patient

Expanded access trial TVI-Brain-1 in a patient with recurrent glioblastoma is no longer available.

CLINICAL_TRIALS trial_result · 2024-09-27

Clinical Trial Update: Predicting Sites of Tumour Progression in the Invasive Margin of Glioblastomas (PRaM-GBM Study)

The PRaM-GBM clinical trial in glioblastoma has completed, providing an update on the study and its aim to predict sites of tumor progressio…

CLINICAL_TRIALS research · 2024-09-27

Clinical Trial Update: The Safety and Efficacy of SNC-109 CAR-T Cells Therapy the rGBM [Phase 1]

Clinical trial update on the safety and efficacy of SNC-109 CAR-T Cells Therapy for recurrent glioblastoma multiforme, currently in Phase 1 …