Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma [Phase 2, Phase 3]
A multi-regimen Phase 2/3 clinical trial in newly diagnosed and recurrent glioblastoma is currently recruiting. The study is sponsored by th…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) [Phase 1]
A Phase 1 clinical trial evaluating RNA-lipid particle vaccines for newly diagnosed pediatric high-grade gliomas and adult glioblastoma is c…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: UNITy-BasED MR-Linac Adaptive Simultaneous Integrated Hypofractionated Boost Trial for High Grade Glioma in the Elderly [Phase 2]
This clinical trial update covers a Phase 2 study of Unity MR-Linac adaptive hypofractionated boost for high-grade glioma in elderly patient…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM [Phase 3]
Phase 3 trial evaluating Sonocloud-9 with Carboplatin versus standard chemotherapy (lomustine or temozolomide) for recurrent glioblastoma; r…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma [Phase 1, Phase 2]
A clinical trial update on LMP744, an indenoisoquinolone Topoisomerase I inhibitor, being studied for recurrent glioblastoma (including IDH-…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma [Phase 1]
A Phase 1 clinical trial evaluating dual-targeting CAR-NK cells for recurrent/progressive glioblastoma and high-grade gliomas is currently r…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas [Phase 1]
This update describes a Phase 1 clinical trial evaluating locoregional administration of EGFR/IL13Rα2 Pool-CAR T cells for recurrent or prog…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM) [Phase 2]
Phase 2 clinical trial evaluating DOC1021 dendritic cell immunotherapy for newly diagnosed adult glioblastoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors
This trial update describes a pediatric brain tumor study using cerebrospinal fluid cell-free tumor DNA; the study was terminated.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Intracranial Injection of NK-92/5.28.z Cells in Combination With Intravenous Ezabenlimab in Patients With Recurrent HER2-positive Glioblastoma [Phase 1]
Phase 1 trial evaluating intracranial NK-92/5.28.z cell therapy in combination with intravenous ezabenlimab for recurrent HER2-positive glio…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant [Phase 2]
Phase 2 clinical trial exploring ribociclib with everolimus or with temozolomide for high-grade gliomas and related diffuse gliomas; recruit…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc [Phase 1]
Phase 1 study of autologous CAR-T cells targeting B7-H3 (CAR.B7-H3Tc) for recurrent or refractory glioblastoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial [Phase 1]
Phase 1 NeoGlioma trial evaluating preoperative radiosurgery for high-grade glioma is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial [Phase 2]
A Phase 2 multicenter trial (MOAB) at Duke University is investigating optimal atezolizumab biomarkers in recurrent glioblastoma and is curr…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence [Phase 2]
Phase 2 clinical trial update examining L19TNF in combination with lomustine for glioblastoma at progression or recurrence; study is current…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Treatment of Recurrent High-Grade Glioma [Phase 1]
Phase 1 trial assessing WSD0628, an ATM inhibitor, in combination with radiation therapy for recurrent high-grade glioma (glioblastoma) is c…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Sitagliptin in Recurrent/Progressive Grade 4 Glioma [Phase 1]
Clinical trial update describing a Phase 1 study of sitagliptin in recurrent or progressive glioma and glioblastoma, with status NOT_YET_REC…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer [Phase 2]
A Phase 2 trial sponsored by Mayo Clinic compares at-home cancer-directed therapy to in-clinic treatment for patients with various advanced …
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Evaluating Safety, Tolerability, and Preliminary Efficacy of YSCH-01 Monotherapy and in Combination With Atezolizumab for Recurrent Glioblastoma [EARLY_Phase 1]
An early-phase clinical trial evaluating YSCH-01 as monotherapy and in combination with atezolizumab for recurrent glioblastoma, focusing on…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Application of FET-PET in Fusion With MRI in the Treatment of Glioblastoma Multiforme [TYR-GLIO] [NA]
This clinical trial investigates applying FET-PET imaging fused with MRI to guide treatment in glioblastoma and is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM [Phase 1]
Phase 1 clinical trial update on a personalized neoantigen cancer vaccine with radiotherapy and pembrolizumab for newly diagnosed glioblasto…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma [Phase 1]
This clinical trial investigates temozolomide (Temodar) in combination with the HDAC inhibitor Abexinostat for recurrent high-grade gliomas,…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: AB154 Combined With AB122 for Recurrent Glioblastoma [EARLY_Phase 1]
A phase 1 trial evaluating AB154 in combination with AB122 for recurrent Glioblastoma; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Study to Test a New Fluid to Improve the Quality of Images Obtained by Using Sound Waves (Ultrasound) During Surgery [NA]
A clinical trial is testing a new fluid to improve ultrasound image quality during brain tumor surgery and is currently recruiting. Sponsor:…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma [Phase 3]
An ongoing Phase 3 clinical trial is evaluating TLX101-Tx plus standard of care vs standard of care alone in patients with recurrent gliobla…