Glioblastoma
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Correlation Between Prostate-specific Membrane Antigen Positron Emission Tomography and Arterial Spin Labeling Perfusion Imaging in Glioblastoma
A completed clinical trial from Lanzhou University Second Hospital investigates the relationship between PSMA-PET imaging and arterial spin …
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients with Glioblastoma [Phase 1]
A Phase 1 trial investigating dexamethasone and azeliragon for post-resection cerebral edema in glioblastoma patients has been withdrawn.
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CLINICAL_TRIALS other · 2024-09-19Clinical Trial Update: Evaluate the Efficacy and Safety of ADCV01 As an Add-On Treatment for Primary Glioblastoma Multiforme (GBM) Patients [Phase 2]
Phase 2 clinical trial evaluating ADCV01 as add-on therapy for primary glioblastoma (GBM) is currently recruiting.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma [NA]
A clinical trial update indicates Northwell Health is recruiting for a study testing a surgical tissue flap to bypass the blood-brain barrie…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Surgical Tissue Flap to Bypass the Blood Brain Barrier in GBM [NA]
This clinical trial investigates using a surgical tissue flap to bypass the blood-brain barrier in glioblastoma. The study is currently acti…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM [Phase 3]
Phase 3 clinical trial evaluating repeated superselective intraarterial infusion of bevacizumab with temozolomide and radiation versus temoz…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) [NA]
This clinical trial update indicates recruitment for a study evaluating omental tissue autograft in patients with recurrent glioblastoma mul…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Neuro/Sacituzumab Govitecan/Breast Brain Metastasis/Glioblastoma/Ph 0 [EARLY_Phase 1]
This entry notes the completion of an early-phase trial evaluating sacituzumab govitecan in glioblastoma.
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CLINICAL_TRIALS research · 2024-08-30Clinical Trial Update: Niraparib and Temozolomide in Patients Glioblastoma [Phase 1, Phase 2]
Early-phase clinical trial evaluating the combination of niraparib and temozolomide in patients with glioblastoma; the study is not yet recr…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Dendritic Cell Vaccine for Patients With Brain Tumors [Phase 2]
Phase 2 trial of an autologous dendritic cell vaccine for brain tumors has completed enrollment and assessment.
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Study of Pembrolizumab Plus SurVaxM for Glioblastoma at First Recurrence [Phase 2]
Phase 2 trial evaluating pembrolizumab plus SurVaxM for recurrent glioblastoma has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM) [Phase 1, Phase 2]
A terminated Phase 1/2 trial evaluating vorinostat, isotretinoin, and temozolomide in adults with recurrent glioblastoma and anaplastic glio…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: CM93 Treatment in Subjects With Epidermal Growth Factor Receptor (EGFR)-Modified Recurrent Glioblastoma (rGBM) [Phase 1]
Phase 1 trial update for CM93 in EGFR-modified recurrent glioblastoma; study status is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: CT Perfusion in the Prognostication of Cerebral High Grade Glioma [NA]
Clinical trial update indicating completion of a study evaluating CT perfusion as a prognostic tool for high-grade glioma (glioblastoma).
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Clinical Study on the Safety and Efficacy of Novel Oncolytic Virus in the Treatment of Recurrent Malignant Glioma [Phase 1, Phase 2]
Clinical trial update indicates a Phase 1/2 study of a novel oncolytic virus for recurrent malignant glioma (including glioblastoma) has bee…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: Open-Label Pilot Study of OPTUNE® With High Density Transducer Arrays for the Treatment of Recurrent GBM [Phase 2]
This document reports the completion of an open-label Phase 2 pilot study evaluating the OPTUNE TTFields device with high-density transducer…
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CLINICAL_TRIALS trial_result · 2024-08-12Clinical Trial Update: [18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers [Phase 1]
Phase 1 trial evaluating the PET tracer [18F]DASA-23 for PKM2 expression in intracranial neoplasms and glioblastoma, including healthy volun…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: TTField in Combination With Temozolomide and Tislelizumab in The Treatment of Newly Diagnosed Glioblastoma. [Phase 2]
Phase 2 trial evaluating tumor treating fields in combination with temozolomide and tislelizumab for newly diagnosed glioblastoma. The curre…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors [Phase 2]
Phase 2 pediatric brain tumor trial evaluating MRI-guided laser heat ablation to disrupt the peritumoral blood-brain barrier in order to imp…
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CLINICAL_TRIALS withdrawal · 2024-08-09Clinical Trial Update: Treatment of Recurrent GBM With APG-157 Via Expanded Access
Expanded-access trial of APG-157 for recurrent glioblastoma has been discontinued and is no longer available.
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Repurposed Drugs in Research for Cancer Clinical Trials- Pitavastatin [EARLY_Phase 1]
An early-phase study evaluated repurposed pitavastatin for glioblastoma in adults, including recurrent disease; the EARLY_PHASE1 trial is co…
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CLINICAL_TRIALS trial_result · 2024-08-05Clinical Trial Update: Methylation Patterns of the NUPR1, MGMT, NDRG2, and GLI1 Genes and Their Impact on Therapeutic Outcome of GBM Patients
A completed clinical trial investigated methylation of NUPR1, MGMT, NDRG2, and GLI1 genes in glioblastoma patients. The study assessed how t…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Surgically Induced Neurological Deficits in Glioblastomas (SIND Study)
The SIND study investigates surgically induced neurological deficits in glioblastoma and is sponsored by Cambridge University Hospitals NHS …
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Glioblastoma Psychosocial Support Program [NA]
A clinical trial evaluating a glioblastoma psychosocial support program has completed.
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CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: Targeted Survivin DC Cell Injection for the Treatment of GBM [Phase 1]
Phase 1 clinical trial of a targeted survivin dendritic cell injection for glioblastoma. The study is sponsored by Beijing Tricision Biother…