Clinical Trial Update: Autologous Dendritic Cells, Metronomic Cyclophosphamide and Checkpoint Blockade in Children With Relapsed HGG [Phase 1, Phase 2]

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Summary

Completed Phase 1/Phase 2 trial in children with relapsed high-grade glioma evaluating autologous dendritic cells with metronomic cyclophosphamide and checkpoin…

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Diseases / indications

• Glioblastoma
• High-grade Glioma

Drugs mentioned

• Autologous dendritic cell therapy (dendritic cells (autologous))
• CYCLOPHOSPHAMIDE (Cyclophosphamide)
• Checkpoint blockade (PD-1/PD-L1 inhibitor)

Snippet

Sponsor: Wuerzburg University Hospital | Conditions: Childhood Glioblastoma | Phase 1, Phase 2 | Status: COMPLETED