Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations [Phase 1, Phase 2]
This clinical trial update reports results from a Phase 1/2 study of BGB-290 in combination with temozolomide in patients with recurrent gli…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma [Phase 1, Phase 2]
A Phase 1/2 trial of Selinexor in combination with standard-of-care therapy for newly diagnosed or recurrent glioblastoma was terminated, wi…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain Tumor [Phase 1, Phase 2]
A clinical trial update describing radiodynamic therapy with Gliolan (5-ALA) for first recurrence glioblastoma, currently recruiting in Phas…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Physical Training in Glioblastoma Patients During Cytotoxic Therapy [NA]
A completed clinical trial evaluating physical training for glioblastoma patients undergoing cytotoxic therapy.
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM [Phase 2]
Clinical trial update for a Phase 2 study comparing nivolumab plus temozolomide versus temozolomide alone in newly diagnosed elderly patient…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme [Phase 2]
This update reports the completion of a Phase 2 trial evaluating hypofractionated stereotactic radiotherapy in recurrent glioblastoma.
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Dendritic Cell Vaccination for Patients with Solid Tumors [Phase 1, Phase 2]
Phase 1/Phase 2 clinical study evaluating a dendritic cell vaccine in patients with solid tumors, including glioblastoma and renal cell carc…
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CLINICAL_TRIALS other · 2024-12-09Clinical Trial Update: Sonodynamic Therapy in Patients With Recurrent GBM [Phase 1]
Clinical Trial Update indicates a Phase 1 sonodynamic therapy trial for recurrent glioblastoma is currently recruiting.
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Study to Evaluate the Safety, Tolerability, Immunogenicity and Preliminary Efficacy of ITI-1001 In Patients With Newly Diagnosed Glioblastoma (GBM) [Phase 1]
Phase 1 clinical trial updating the safety, tolerability, immunogenicity, and preliminary efficacy of ITI-1001 for newly diagnosed glioblast…
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CLINICAL_TRIALS withdrawal · 2024-12-04Clinical Trial Update: Lenvatinib, Pembrolizumab, and Tumor Treating Fields (TTFields) for Second-line Treatment of Glioblastoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating lenvatinib, pembrolizumab, and Tumor Treating Fields for second-line glioblastoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-12-02Clinical Trial Update: Efficiency of Vaccination with Lysate-loaded Dendritic Cells in Patients with Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 clinical trial evaluating a lysate-loaded dendritic cell vaccine in newly diagnosed glioblastoma patients; the study is currently ac…
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CLINICAL_TRIALS research · 2024-11-29Clinical Trial Update: Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade Gliomas [Phase 1, Phase 2]
Clinical trial updating a Phase 1/2 study of liposomal curcumin with radiotherapy and temozolomide for newly diagnosed glioblastoma; recruit…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: A Pilot Surgical Trial To Evaluate Early Immunologic Pharmacodynamic Parameters For The PD-1 Checkpoint Inhibitor, Pembrolizumab (MK-3475), In Patients With Surgically Accessible Recurrent/Progressive Glioblastoma [Phase 1]
Phase 1 pilot study update of pembrolizumab in surgically accessible recurrent/progressive glioblastoma. The study investigates early immuno…
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CLINICAL_TRIALS research · 2024-11-26Clinical Trial Update: Function and Composition of Regulatory B Cells in Participants With Glioblastoma
This document provides an update on a clinical trial investigating regulatory B cells in adults with glioblastoma; the study status is termi…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Patient-derived Glioma Stem Cell Organoids
A clinical trial update describing a study using patient-derived glioma stem cell organoids for glioblastoma, with the trial currently not r…
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CLINICAL_TRIALS withdrawal · 2024-11-20Clinical Trial Update: Randomized Study of Neo-adjuvant and Adjuvant Pembrolizumab With and Without Targeted Blood Brain Barrier Opening Using Exablate MRI-guided Focused Ultrasound (Exablate MRgFUS) for Recurrent Glioblastoma [Phase 2]
The Phase 2 randomized trial evaluating pembrolizumab with and without Exablate MRgFUS for recurrent glioblastoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: NovoTTF-200A and Temozolomide Chemoradiation for Newly Diagnosed Glioblastoma [Phase 1]
Phase 1 trial evaluating NovoTTF-200A (Optune) with temozolomide chemoradiation for newly diagnosed glioblastoma. The study status is comple…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: WL276 CAR-T Cell Therapy for CD276 Positive Recurrent or Progressive Glioblastoma Patients [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating WL276 CAR-T cell therapy targeting CD276 in patients with recurrent or progressive glioblastoma; …
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Brain Tumor Intraoperative Ultrasound Database
The Brain Tumor Intraoperative Ultrasound Database study has completed its clinical trial.
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Blood and Cerebrospinal Fluid Metabolomic Profile in Glioma Patients
This completed trial reports the metabolomic profiles in blood and cerebrospinal fluid from patients with glioma, including glioblastoma.
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: Optimizing Cytokine-Induced Killer Cells in Glioblastoma Patients
A clinical trial registry entry describing optimization of cytokine-induced killer cells for glioblastoma, currently not recruiting.
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: 18F-FDG PET and Osimertinib in Evaluating Glucose Utilization in Patients with EGFR Activated Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating Osimertinib with 18F-FDG PET to assess glucose utilization in EGFR-activated recurrent glioblastoma; the study has …
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Sonodynamic Therapy With ExAblate System in Glioblastoma Patients [Phase 2]
Phase 2 trial update shows completion of testing of sonodynamic therapy with the ExAblate system in glioblastoma patients.
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma [Phase 1]
A Phase 1 trial evaluating Lapatinib Ditosylate before surgical resection in adults with recurrent high-grade glioma has completed. The stud…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: PARP Inhibition for Gliomas (PI-4G or π4g) [Phase 2]
Phase 2 trial of a PARP inhibitor for gliomas was terminated, with results posted in 2024, evaluating recurrent glioblastoma, recurrent astr…