Glioblastoma
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Assessment of Optune Therapy for Patients With Newly Diagnosed Glioblastoma Using Advanced MRI
Clinical trial update on Optune tumor-treating fields therapy for newly diagnosed glioblastoma, incorporating advanced MRI, with status list…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme [Phase 3]
Phase 3 trial investigating intraoperative radiotherapy for newly diagnosed glioblastoma multiforme. The study is sponsored by Universitätsm…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor Cancer [Phase 1]
A Phase 1 study evaluating TAS2940 in locally advanced or metastatic solid tumors has been terminated. The trial enrolled patients with glio…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Clinical Trial to Assess the Efficacy and Safety of 'Immuncell-LC' With Temozolomide in Newly Diagnosed Glioblastoma of Korea [Phase 3]
Phase 3 trial evaluating Immuncell-LC with temozolomide in newly diagnosed glioblastoma completed in Korea; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins. [EARLY_Phase 1]
An early-phase study evaluating the Ga-68 labeled FF58 radiotracer in selected solid tumors overexpressing integrins has been terminated.
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the combination of radiation therapy with a DLL3-targeting bispecific T-cell engager in DLL3-expres…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma [Phase 1]
Phase 1 clinical trial evaluating the combination of Laser Interstitial Thermal Therapy (LITT) with Lomustine (CCNU) for recurrent glioblast…
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells [Phase 1, Phase 2]
A Phase 1/2 clinical study evaluating the relationship between metabolic MR-PET imaging and tissue glycolysis in infiltrating glioblastoma b…
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastoma [Phase 1]
Phase 1 study of pembrolizumab, vorinostat, and temozolomide in newly diagnosed glioblastoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma [Phase 1]
Phase 1 clinical trial evaluating repeated neural stem cell based virotherapy for newly diagnosed high-grade glioma.
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma [Phase 1]
Phase 1 study of chlorotoxin-targeted CAR T cells targeting MMP2 in patients with recurrent glioblastoma and other recurrent gliomas. The tr…
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients [Phase 1, Phase 2]
This clinical trial update indicates ongoing Phase 1/2 studies of D2C7-IT and 2141-V11 for newly diagnosed MGMT unmethylated glioblastoma, c…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma [Phase 2]
This clinical trial entry notes a Phase 2a study from Northwestern University evaluating ultrasound-based immune modulation for newly diagno…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients
Expanded Access program for AVM0703 is available to eligible patients with several solid tumor and blood cancer indications, including gliob…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Pharmacoscopy for Patients With Refractory Primary Brain Tumors [Phase 2]
Phase 2 clinical trial update for pharmacoscopy in patients with refractory primary brain tumors, currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial [Phase 2]
This Phase IIc randomized feasibility pilot trial evaluated cognitive behavioral therapy for insomnia in patients with primary brain tumors …
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma [Phase 1]
A Phase 1 clinical trial update exploring ibrutinib in combination with radiation and temozolomide for newly diagnosed glioblastoma; the stu…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Clinical and Treatment Determinant of Prognosis in Glioblastoma
Update on a clinical trial examining clinical and treatment determinants of prognosis in glioblastoma; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Stupp Treatment With Intrathecal Injection of Thiotepa for Glioblastoma With Advanced Spread [Phase 2]
A Phase 2 clinical trial is evaluating intrathecal thiotepa added to Stupp treatment for glioblastoma with advanced spread, and the study is…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: G-CSF After Chemo-radiation in Patients With Glioblastoma [Phase 2]
This document reports a Phase 2 clinical trial evaluating the use of granulocyte colony-stimulating factor (G-CSF) after chemotherapy and ra…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating atezolizumab in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma has…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Memory Perception Assessment in Central/Non-central Nervous System Cancers [NA]
Clinical trial update on memory perception assessment in central and non-central nervous system cancers; the study includes glioblastoma and…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: hPG80 (Circulating Progastrin) as a Blood Biomarker for High-grade Glial Tumors
This update covers results from a completed clinical trial evaluating circulating progastrin (hPG80) as a blood biomarker for high-grade gli…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: DLL3 CAR-T Therapy Targeting Brain Tumors [Phase 1, Phase 2]
This document reports an ongoing phase 1/2 clinical trial of a DLL3-targeted CAR-T therapy for glioblastoma that is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial [Phase 2]
A Phase 2 hybrid randomized trial is evaluating enhanced local intensified radiation therapy for elderly patients with glioblastoma and is c…